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20 Cards in this Set

  • Front
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Cellular Respiration

how cells get energy from organic molecules and release waste.

Goal of Cellular Respiration

ATP Synthesis/production

Glucose

a fuel molecule


- when oxidized into CO2 and water, ATP, NADH, and FADH2 are made.

Aerobic Cellular Respiration

- breakdown of fuel molecules in the presence of O2.


- 1 molecule of glucose oxidized generates up to 38 ATP.

Metabolic pathways

-glycolysis


- transition reaction


- citric acid cycle


- oxidative phosphorylation

Glycolysis

- occurs in cytoplasm


- summary: glucose molecule become 2 pyruvate molecules


- must be regulated


- Energy Yield: 2 ATP (net) and 2 NADH

Reactions of glycolysis

- energy investment phase


- cleavage phase


- energy liberation phase

Energy Investment Phase

glucose is converted to 6 biophosphate

Cleavage Phase

6 biophosphate (6 carbon molecule) becomes 2 3-carbon molecules

Energy Investment phase

2 3-carbon molecules become 2 molecules of pyruvate

Regulation of glycolysis

if enough ATP is present, then:


- ATP binds w/enzyme at allosteric site


- glucose breakdown and ATP overproduction is inhibited.

Transition Reaction

- pyruvate molecules transported to mitochondrion


- pyruvate oxidized into a Acetyl group and CO2


- CO2 exhaled


- 2 NADH form


Energy Yield: 2 NADH


Citric Acid Cycle (Kreb's Cycle)

- requires oxygen


- occurs in mitochondrion


-Acetyl group removed from CoA


Energy Yield: 10 NADH, 2 FADH2, and 2 ATP



Oxidative Phosphorylation

involves:


- electron transport chain and ATP synthesis


- electron are removed from NADH and FADH2 to make more ATP


- Energy Yield: 34 ATP

Electron Transport Chain

group of protein complexes and organic molecules in mitochondiral membrane

ATP Synthase

- create ATP through chemiosmosis


- energy source: H+ electrochemical gradient as


- exergonic process

Lipid Metabolism

- fats typically broken down to glycerol and fatty acids

Anaerobic Respiration

- fuel molecules metabolized without O2


- molecule (that's not O2) must substitute as final electron acceptor in ETC


- H+ gradient powers ADP + Pi to ATP conversion


- yield varies


ex: many bacterial species live under anaerobic conditions

Fermentation

- no net oxidation of molecules


- Net Yield: 2 ATP


- ATP synthesized by glycolysis



Problems with fermentation

- [NAD+] decreases


- NAD+ is needed to continue glycolysis


- high [NADH] donates electrons to molecules and forms free radicals (which are bad)