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10 Cards in this Set
- Front
- Back
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End-to-end bias of nucleic acids |
Goes 5' to 3' where the 5' is the free phosphate group and the 3' is the hydroxyl group. |
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What direction are nucleic acids synthesized? |
5'-3' |
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What is the 3D structure of DNA |
double stranded, where phosphodiester backbones are outside and the bases are inside where A and T are bonded and C and G are bonded. Both have end bias. |
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B-DNA is |
regular, most common DNA. |
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A-DNA is |
shorter and wider with smaller number of nucleotides |
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Z-DNA is |
longer and thinner DNA |
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What is the Tm point? |
where 50% of the DNA is denatured. It is dependent on the G-C bond because they have three hydrogen bonds (not two) so it takes longer to break |
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Different Structures for RNA |
Hairpin: Single folded RNA Stem-loop: larger hairpin Tertiary: Pseudoknot where two stem-loops are are joined. FORM = FUNCTION |
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Protein Hierarchy |
Primary sequence: straight chain of A.A. N-terminus and C-terminus Secondary structure: localized folding of primary. Alpha helix, beta sheets, beta turns Tertiary structure: using the helices, sheets and turns to make Quaternary structure: using identical or almost identical tertiary structures to make one structure Supramolecular: tens of hundreds of polypeptides made into one. |
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Motif/Domains |
regions of polypeptides that have functional characteristics. |
