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50 Cards in this Set

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Cells
coined by Robert Hooke in 1665; describes the individual units observed in thin sections of cork
Cell Theory
cells are the basic building blocks of all plants and animals; come from division of pre-existing cells; smallest units that perform all vital physiological functions; maintains cellular homeostasis
Homeostasis of body
determined by homeostasis of the cells; combined and coordinated efforts of cells give tissues, organs, organ systems, and organisms homeostasis
Classes of Cells
sex cells
somatic cells
Sex cells
germ cells; reproductive cells; sperm cells in males; oocytes (ova or eggs) in females
Somatic cells
soma=body; all non-sex cells of the body
Extracellular fluid
surrounds cells in human body; means outside of cell
Interstital Fluid
extracellular fluid in tissue; means standing between
Plasma Membrane
aka cell membrane
sepaates cell from extracellular fluid; thin layer
cytoplasm
inside the cell; mostly water
cytosol
liquid portion of cytoplasm
organelles
intracellular structures suspended in cytoplasm
Nucleus
nuclear membrane; DNA
Plasm membrane functions
Physical separation - inside from external fluid; Regulates exchange - controls entry of nutrients and ions and exit of waste and secretions; sensitive to environment - recepotrs respond to environment; structural support - tissue stability
Plasma Membrane contents
lipids
proteins
carbs
Phospholipid bilayer
2 layers; phospate = hydrophillic; lipid = hydrophobic; hydrophillic head at membrane surface near tissue fluid and cell fluid; hydrophobic tals on inside away from fluid
Membrane Proteins and functions
float in phospholipid bilayer of plasma membranes;
Functions: anchors, recognition, enzymes, receptors, carriers, channels
Anchors
mp; attach to cytoskeleton in cytoplasm; attach to extracellular filament or to other cells
Recognition
mp; self v. non-self
- immune system
Enzymes
mp; catalyze reactions
receptors
mp; bind to ligands
- triggers changes
Carriers
mp;binds solutes and carries them across plasm membrane; may require energy from ATP
Channels
mp; pores; passageway for water and ions; may be specific
Membrane Carbs
small %; glycocalyx; lubrication; protection; sticky - locomation- anchor; specificity; recognitino
Plasma Membrane characteristics...
an effective barrier; continuous, uniform; has selective permeability
Selective Permeability
determines what can either enter or exit the membrane
Types of Passage across the membrane
passive
active
Types of Passive transport across the membrane
diffusion; osmosis; facilitated diffusion
transports that require ATP (energy)
active
secondary active
vesicular transport
- endocytosis
- exocytosis
Endocytosis
receptor-mediated endocytosis
pinocytosis
phagocytosis
Diffusion
passive;
ions and molecules;
movement from area of high concentration to area of low concentration;
reduces the concentration gradient
Concentration Gradient
difference between the high and low concentration
Rates of Diffusion
- increases with increase in concentration gradient
- increases as temp increases
- increases as molecule size decreases
- increases as distance decreases
- increases with electrical forces
Osmosis
passive;
diffusion of water molecules;
moves from area of high water concentration to area of low water concentration;
equilibrium
Osmotic Pressure
force with which pure water moves;
more force needed as number of particles dissolved in the solution increases
Facilitated Diffusion
passive;
transports nutrients such as glucose that are not soluble in lipids and too lg. for simple diffusion;
molecule binds to receptor on carrier protein;
movement is in difection of concentration gradient so no ATP is required
Carrier Protein
shapes changes and moves the molecule across the membrane
Active Transport
ATP provides energy; moves substances against gradient; carrier proteins = ion pumps; Na-K exchange pump
Active Transport Homeostasis
maintained by moving K+ back into cell and ejecting extra Na+ out of cell
Secondary Active Transport
does not use ATP across membrane but to maintain cell homeostasis; carrier protein moves substrate w/o regard to gradient at same time; c. gradient of 1 substance provides force for moving second subtance (free ride)
Vesicular Transport
transporting bulk; membranes are moved in sm. sacs made of membrane (vesicles)
Types of Vesicular Transport
endocytosis
exocytosis
Endocytosis
moved into cell; extracellular materials packaged in vesicles; requires ATP
types of endocytosis
receptor-mediated endocytosis
pinocytosis
phagocytosis
Receptor-mediated endocytosis
materials bind to recognition receptors on cell surface;
ex. cholesterol and iron
Process of receptor-mediated endocytosis
1. recepters are glycoprotein and bind to ligands
2. receptors w. bound ligands clust together
3. pinches off into coated vesicle
4. coated vesicle fuses w. lysosomes that contain digestive enzymes
5. digestive enzymes free ligands which enter cytosol by diffusion
Ligands
specific target that receptors of receptor-mediated endocytosis bind to
Pinocytosis
endocytosis; cell drinking; vesicles filled w. extracellular fluid; no receptor
Phagocytosis
endocytosis; cell eating; cells form pseudopods that surround solid to be brought into the cell; may be as large as the cell; phagosome vesicle fuses with lysosome and is digested by enzymes; ex. white blood cell destroying bacteria
Exocytosis
vesicle inside the cell fuses with plasma membrane; releases contents; homrones; waste