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28 Cards in this Set
- Front
- Back
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Normal BP
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Systolic <130mm
Hg Diastolic <85mm Hg |
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High Normal
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add 10 to normal sys, 5 to normal dia
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Hypertension
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each stage add 20 to sys and 10 to dia
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What is blood pressure
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CO X SVR
cardiac output x systemic vascular resistance |
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Adrenergic agents MoA
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Block the alpha 1-adrenergic receptors
RESULT: Decreased BP |
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Central - Acting Adrenergics...
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...stimulate alpha2-adrenergic receptors
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Name a Central-Acting Adrenergic
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Catapres
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Alpha 1 blockers are _____ ____
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peripherally acting
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Alpha 1 blocker relieve_______ and manage______
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symptoms of BPH
severe CHF |
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Peripherally acting adernergic neuronal blockers are seldom used because of...
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...frequent side effects
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ACE Inhibitors are
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Angiotensin-Converting Enzyme Inhibitors
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ACE Inhibitors info
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-large group of SAFE and effective drugs
-often used as first-line agents for CHF and hypertension |
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ACE MoA
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-Aldosterone stimulates water and sodium resorption
-Results in increased blood volume, increased preload, increased B |
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ACE Inhibitors block the _____-_____ enzyme, thus preventing the formation of _______ __
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angiotensin-converting
angiotensin II |
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They also prevent the breakdown of the _____ substance, _____
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vasodilating
bradykinin |
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The result is decreased___ ___ ___, vasodilation and therefore ___ ___ ___
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systemic vascular resistance (afterload)
decreased blood pressure |
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Name an ACE inhibitor
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Vasotec
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What is the drug type of choice in hypertensive pts with CHF
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ACE Inhibitors
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ACE side effects
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dry non-productive cough
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What is an upside of Angiotensin II Receptor Blockers (ARB's)
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newer class
well-tolerated don't cause coughing |
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ARB MoA
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-Allow angiotensin I to be converted to angiotensin II, but block the receptors that receive angiotensin II
-Block vasoconstriction and release of aldosterone |
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Types of Calcium Channel Blockers
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-Benzothiazepines
-Dihydropyridines -Phenlalkylamines |
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CCB MoA
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Cause smooth muscle relaxatio by blocking the binding of calcium to its receptors, preventing muscle contraction
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Type of Benzothiazepine
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Cardizem
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Type of Dihydropyridine
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Norvasc, Cardene
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Calcium Channel Blockers are for...
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...Angina
Hypertension Dysrhythmias Migranes |
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Diuretics do what...
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Decrease the plasma and extracellular fluid volumes
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Vasodilators do what...
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directly relax arteriolar smooth muscle
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