Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
18 Cards in this Set
- Front
- Back
IL-1
HOT |
Secreted by macrophages.
Causes acute inflammation. Induces chemokine production to recruit leukocytes; activates endothelium to express adhesion molecules. An endogenous pyrogen. Goljan: osteoclast activating factor. |
|
IL-2
T |
Secreted by helper T cells.
Stimulates growth of helper and cytotoxic T cells. |
|
IL-3
BONE |
Secreted by activated T cells.
Supports the growth and differentiation of bone marrow stem cells. Has a function similar to granulocyte-macrophage colony stimulating factor. |
|
IL-4
stEak |
Secreted by Th2 cells.
Promotes growth of B cells. Enhances class switching to IgE and IgG. |
|
IL-5
steAk e= 5th letter of the alphabet. |
Secreted by Th2 cells. Promotes differentation of B cells.
Enhances class switching to IgA. Stimulates production and activation of eosinophils. (5th letter of the alphabet) |
|
IL-6
|
Secreted by Th cells and macrophages.
Major chemotactic factor for neutrophils. |
|
IL-8
Clean up on aisle 8 |
Secreted by macrophages.
Major chemotactic factor for neutrophils. |
|
IL-10
|
Secreted by regulatory T cells.
Inhibits actions of activated T cells. Activates Th2, inhibits Th1. |
|
IL-12
|
Secreted by B cells and macrophages.
Activates NK and Th1 cells. |
|
gamma-INF
|
Secreted by Th1 cells.
Stimulates macrophages. Activates Th1, inhibits Th2. |
|
TNF (Tumor Necrosis Factor)
|
Secreted by macrophages.
Mediates septic shock. Causes lekocyte recruitment, vascular leak. |
|
Secreted by macrophages:
|
IL-1
IL-6 IL-8 IL-12 TNF |
|
Secreted by Th cells:
|
IL-2
IL-6 |
|
Secreted by activated T cells:
|
IL-3
|
|
Secreted by Th2 cells:
|
IL-4
IL-5 |
|
Secreted by regulatory T cells:
|
IL-10
|
|
Secreted by B cells:
|
IL-12
|
|
Secreted by Th1 cells:
|
gamma-INF
|