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3 Cards in this Set
- Front
- Back
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What does gnotobiotic mean?
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Germ-free
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How can we establish colonies of gnotobiotic animals and birds?
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We isolate offspring using sterile techniques and raising them in germ free enviornments
-In mammals we do this by a cesarean section -For birds, exterior surface of egg is sterilzed -Once first generation has been established, they can be maintained and bred in germ free environments |
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What are characteristics of gnotobiotic animals and birds?
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1) Abnormal anatomical and physiological features
2) Underdeveloped lymphatic tissue and poorly developed immune systems 3) Thin intestinal wall 4) Low antibody titer (concentration) 5) Higher susceptibility to pathogens 6) Reduced susceptibility to certain disease processes which are dependent on the activity of microbes |
