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25 Cards in this Set
- Front
- Back
Role of histology department |
Produce accurate diagnostic information from patient tissue samples by studying thin slices of the tissue under the microscope Many diseases produce predictable/typical structural changes that can be interpreted |
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Role of lab assistants |
Book in samples Order supplies |
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Role of biomedical scientist |
Processing Embedding Sectioning Staining Quality control checks Quality assurance Advanced practitioners- can perform cut ups and report on some specimen grades |
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Role of pathologist |
Initial cut up Interpretation of results Post mortem examinations |
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Secretarial staff |
Enter patients on top the LMS Transcribe the macroscopic descriptions |
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From sample to slide |
Biopsy - fixation- transportation- booking in- tissue selection- macroscopic description-processing- embedding- microtomy- Staining- mounting- reporting- LMS entry |
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Excision biopsy |
Complete removal of diseased tissue with a margin of healthy tissue |
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Sample adequacy |
Tissue sample representative of disease states of all of the tissue No false negatives when disease is present |
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What is quality management? |
Ensuring all activities are carried out effectively and efficiently with respect to system and performance |
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Role of quality managers |
Interpretation quality manager system and implement quality policy, objectives |
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Cells |
Basic unit of structure |
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Tissues |
Various cells combine to perform a specialised function |
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Organs |
Comprised of different tissues that work cooperatively |
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Systems |
Composed of organs that work cooperatively |
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4 basic types of tissue |
Epithelial Connective Muscle Nervous |
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Role of epithelial cells |
Cover body surfaces, line body cavities and form glands Avascular Protection Absorption Filtration Excretion Secretion Cells are in close proximity to each other and form sheets They are polar- have an apical and basal surface Regenerative capacity |
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Epithelial cell classification |
According to microscopic shape and layering structure Shape- squamous, cuboidal, Columnar Layering- simple, pseudo stratified and stratified Shape+ layering= type |
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Role of connective tissue |
Provide physical support Bind other structures together Provide transport system (blood) Provide insulation (fat) Protection Provide immune functions |
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Types of connective tissue |
Loose - adipose and reticular Dense- ligaments, elastic fibres Cartilage- hyaline, elastic, fibrocartilage |
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Role of nervous tissue |
Conduct electrical impulses Complimented by various support cells Found in brain, spinal cord and nerves |
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Nervous tissue supporting cells |
Schwann cells form myelin around myelinated axons Glial cells are the most numerous cells in the immune system - oligodendroglia- form processes ending in myelin that wrap an axon segment - Astroglia- star shaped cells interacting with capillaries and neurones - microglia- macrophage function - ependymal cells- line central cavities of brain and spinal cord |
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Role of muscle tissue |
Highly vascularised tissue composed of elongated cells containing myofilaments actin and myosin Three types - skeletal, cardiac and smooth |
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Skeletal muscles |
Long cylindrical cells with visible striations Multinucleate Facilitate voluntary movement Epimysium - covers outer surface of muscle Penmysium- covers each fascicle Endomysium- covers each fibre |
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Cardiac muscle |
Formation wall of heart Under autonomic control Uninucleate Short and thick Branching cells form intercalated discs |
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Smooth muscle |
Lines the walls of many organs Contraction is under autonomic control Elongated Uninucleate Non-striated Transverse and longitudinal |