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14 Cards in this Set
- Front
- Back
In which tissue are intercalated disks found?
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cardiac tissue
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Epimysium
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In skeletal muscle, an external sheath of dense connective tissue surrounding the entire muscle
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Perimysium
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In skeletal muscle, connective tissue around each BUNDLE of muscle fiber
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Endomysium
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In skeletal muscle, delicate layer of connective tissue surrounding each muscle FIBER
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What protein is present in endomysium? Where else is it present?
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laminin; nerve fibers
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How long are thick filaments? Which band do they occupy?
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1.6 um; A band
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What is responsible for tying adjacent sarcomeres together? Where are they located?
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alpha-actinin and desmin; along Z-line
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What is the major protein of the M-line
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creatine kinase
-catalyzes the transfer of a PO4- group from phosphocreatine to ADP, thus making ATP for muscle contraction |
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Tropomyosin
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long, thin m/c about 40nm in length
made of 2 polypeptide chains bound head to tail, running over actin subunits |
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TnT
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Troponin component that strongly attaches to tropomyosin
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TnC
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Troponin component that binds Ca ions
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TnI
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Troponin component that inhibits actin-myosin interactions
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How and why are cross-bridges formed?
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By head of myosin molecule plus short part of its rodlike portion; converts chemical energy to mechanical energy
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Where are triads located in mammalian skeletal muscle?
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There are two for each sarcomere in this muscle - located at the A-I band junction
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