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113 Cards in this Set
- Front
- Back
Abdominal pain, ascites, hepatomegaly |
Budd-Chiari syndrome (posthepatic thrombosis)
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Achilles tendon xanthoma
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Familial hypercholesterolemia
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Adrenal hemorrhage, hypotension, DIC
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Waterhouse-Friderichsen syndrome (meningococcemia)
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Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints
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Marfan's syndrome (fibrillin defect)
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Back pain, fever, night sweats, weight loss
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Pott's disease (vertebral tuberculosis)
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Big toe extension/fanning upon plantar scrape
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Babinki's sign (UMN lesion)
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Bilateral hilar adenopathy, uveitis
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Sarcoidosis (noncaseating granulomas)
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Blue sclera
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Osteogenesis imperfecta (collagen defect)
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Bluish line on gingiva
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Burton's line (lead poisoning)
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Bone pain, bone enlargement, arthritis
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Paget's disease of bone (up osteoblastic and osteclastic activity)
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Café-au-lait spots, Lisch nodules (iris hamartoma)
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Neurofibromatosis type I (+bilateral acoustic neuromas=type II)
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Calf Pseudohyperthrophy
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Muscular dystrophy (most commonly Duchenne's)
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"Cherry-red spot" on macula
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Tay-Sachs (ganglioside accumulation) or Niemann-Pick (lysosomal storage disease)
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Chest pain, pericardial effusion friction rub, persistent fever following MI
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Dressler's syndrome (autoimmune-mediated post-MI fibrinous pericarditis)
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Child uses arms to stand up from squat
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Gower's sign (Duchenne muscular dystrophy: X-linked recessive deleted dystrophin gene)
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Child with fever develops red rash on face that spreads to body
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"Slapped cheeks" (erythema infectiosum/fifth disease: parvovirus B19)
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Chorea,dementia, caudate degeneration
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Huntington's disease (autosomal-dominant CAG repeat expansion)
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Chronic exercise intolerance with myalgia, fatigue, painful cramps
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McArdle's disease (muscle phosphorylase deficiency)
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Cold intolerance
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Hypothyroidism
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Conjugate lateral gaze, horizontal diplopia
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Internuclear orphthalmoplegia (damage to MLF; bilateral [multiple sclerosis], unilateral [stroke])
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Continuous "machinery" heart murmur
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PDA (close with indomethacin; open with misoprostol [PGE1])
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Cutaneous/dermal edema due to connective tissue deposition
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Myxedema (hypothyroidism, Grave's disease)
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Dark purple skin/mouth nodules
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Kaposi's sarcoma (usually AIDS patients [gay men]: associated with HHV-8)
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Deep, labored breathing/hyperventilation
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Kussmaul breathing (diabetic ketoacidosis)
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Dermatitis, dementia, diarrhea
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Pellagra (niacin [vitamin B3] deficiency)
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Dilated cardiomyopathy, edema, polyneuropathy
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Wet beriberi (thiamine [vitamin B1] deficiency)
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Dog or cat bite resulting in infection
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Pasteurella multocida
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Dry eyes, dry mouth, arthritis
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Sjogren's syndrome (autoimmune destruction of exocrine glands)
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Dysphagia (esophageal webs), glossitis, iron deficiency anemia
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Plummer-Vinson syndrome (autoimmune destruction of exocrine glands)
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Elastic skin, hypermobility of joints
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Ehlers-Danlos syndrome (collagen defect)
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Enlarged, hard left supraclavicular node
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Virchow's node (abdominal metastasis)
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Erythrodema, lymphadenopathy, hepatosplenomegaly, atypical T cells
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Sezary syndrome (cutaneous T-cell lymphoma) or mycosis fungoides
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Facial muscle spasm upon tapping
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Chvostek's sign (hypocalcemia)
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Fat, female, forty, and fertile
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Acute cholecystitis (bile duct blockage)
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Fever, chills, headache, myalgia following antibiotic treatment for syphilis
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Jarisch-Herxheimer reaction (rapid lysis of spirochetes results in toxin release)
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Fever, cough, conjunctivitis, coryza, diffuse rash
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Measles (Morbillivirus)
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Fever, night sweats, weight loss
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B symptoms (lymphoma)
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Fibrous plaques in soft tissues of penis
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Peyronie's disease (connective tissue disorder)
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Gout, mental retardation, self-mutilating behavior in a boy
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Lesch-Nyhan syndrome (HGPRT deficiency)
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Green-yellow rings around peripheral cornea
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Kayser-Fleischer rings (copper accumulation from Wilson's disease)
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Hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands
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Peutz-Jeghers syndrome (genetic benign polyposis can cause bowel obstruction; increase cancer risk)
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Hepatosplenomegaly, osteoporosis, neurologic symptoms
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Gaucher's disease (glucocerebrosidase deficiency)
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Hereditary nephritis, sensorineural hearing loss, cataract
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Alport's syndrome (collagen mutation)
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Hypercoagulability (leading to migrating DVTs and vasculitis)
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Trousseau's sign (adenocarcinoma of pancreas or lung)
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Hyperphagia, hypersexuality, hyperorality, hyperdocility
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Kluver-Bucy syndrome (bilateral amygdala lesion)
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Hypertension, hypokalemia, metabolic acidosis
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Conn's syndrome (1° hyperaldosteronism)
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Hypoxemia, polycythemia, hypercapnia
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"Blue bloater" (chronic bronchitis: hyperplasia of mucous cells)
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Indurated ulcerated genital lesion (nonpainful)
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Chancre (1° syphillis, Treponema pallidum)
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Infant with failure to thrive, hepatosplenomegaly, neurodegeneration
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Niemann-Pick disease (genetic sphingomyelinase deficiency)
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Infant with hypoglycemia, failure to thrive, and hepatomegaly
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Cori's disease (debranching enzyme deficiency)
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Infant with microcephaly, rocket -bottom feet, and structral heart defect
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Edwards's syndrome (trisomy 18)
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Jaundice, RUQ pain, fever
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Charcot's triad 2 (ascending cholangitis)
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Keratin pearls on a skin lesion
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Squamous cell carcinoma
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Large rash with bull's-eye appearance
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Erythema chronicum migrans from tick bite (Lyme disease: Borrelia)
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Lucid interval after traumatic brain injury
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Epidural hematoma
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Male child, recurrent infections, no mature B cells
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Bruton's disease (X-linked agammaglobulinemia)
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Mucosal bleeding and prolonged bleeding time
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Glanzmann's thrombasthenia (defect in platelet aggregation due to lack of Gpllb/llla)
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Multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth
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Gardner's syndrome (genetic disorder, predisposes to colon cancer)
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Necrotizing vasculitis (lungs) and necrotizing glomerulonephritis
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Wegener's and Gooodpasture's syndromes (hemoptysis and glomerular disease)
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Neonate with arm paralysis following difficult birth
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Erb-Duchenne palsy (superior trunk [C5-C6] brachial plexus injury: "waiter's tip")
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No lactation postpartum, absent menstruation, cold intolerance
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Sheehan's syndrome (pituitary infarction)
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Nystagmus, intention tremor, scanning speech
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Charcot's triad 1 (multiple sclerosis)
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Oscillating slow/fast breathing
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Cheyne-Strokes respirationa (central apnea in CHF or ↑ intracranial pressure)
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Painful blue fingers/toes, hemolytic anemia
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Cold agglutinin disease (autoimmune hemolytic anemia caused by Mycoplasma pneumoniae infectious mononucleosis)
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Painful , pale, cold fingers/toes
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Raynaud's syndrome (vasospasm in extremities)
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Painful, raised red lesions on palms and soles
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Osler's node (infective endocarditis)
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Painless jaundice
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Cancer of the pancreatic head obstructing bile duct
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Palpable purpura, joint pain, abdominal pain (child)
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Henoch-Schonlein purpura (IgA vasculitis affecting skin and kidneys)
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Pancreatic, pituitarym parathyroid tumors
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Wermer's syndromee (MEN 1)
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Pink complexion, dyspnea, hyperventilation
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"Pink puffer" (emphysema:centroacinar [smoking], panacinar [α₁-antitrypsin defeciency])
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Polyostotic fibrous dysplasia, precocious puberty, café-au-lait spots, short statue in a young girl
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McCune-Albright syndrome (mosaic G-protein signaling mutation)
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Polyuria, acidosis, growth failure, electrolyte imbalances
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Fanconi's syndrome (proximal tubular reabsorption defect)
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Positive anterior "drawer sign"
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Anterior cruciate ligament (ACL) injury
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Ptosis, miosis, anhidrosis
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Horner's syndrome (sympathetic chain lesion)
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Pupil accommodates but doesn't react
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Argyll Robertson pupil (neurosyphilis)
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Rapidly progressive leg weakness that ascends (following GI/upper respiratory infection)
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Guillain-Barre syndrome (autoimmune acute inflammatory demyelinating polyneuropathy)
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Rash on palms and soles
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2°syphilis, Rocky Mountain spotted fever
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Recurrent colds, unusual eczema, high serum IgE
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Job's syndrome (hyper-IgE syndrome: neutrophil chemotaxis abnormality)
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Red "currant jelly" sputum
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Klebsiella pneumoniae
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Red, itchy, swollen rash of nipple/areola
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Paget's disease of the breast (represents underlying neoplasm)
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Red urine in the morning
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Paroxysmal nocturnal hemoglobinuria
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Renal cell carcinoma, hemangioblastomas, angiomatosis, pheochromocytoma
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von Hippel-Lindau disease (dominant tumor suppressor gene mutation)
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Resting Tremor, rigidity, akinesia, postural instability
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Parkinson's disease (nigrostriatal dopamine depletion)
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Restrictive cardiomyopathy (juvenile form: cardiomegaly), exercise intolerance
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Pompe's disease (lysosomal glucosidase deficiency)
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Retinal hemorrhages with pale centers
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Roth's spots (bacterial endocarditis)
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Severe jaundice in neonate
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Crigler-Najjar syndrome (congenital unconjugated hyperbilirubinemia)
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Severe RLQ pain with rebound tenderness
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Mcburney's sign (appendicitis)
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Short stature, ↑incidence of tumors/leukemia, aplastic anemia
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Fanconi's syndrome (genetically inherited; often progresses to AML)
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Single palm cease
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Simian crease (Down syndrome)
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Situs inversus, chronic sinusitis, bronchiectasis
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Kartagener's Syndrome (dynein defect affecting cilia)
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Skin Hyperpigmentation
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Addison's disease (1° adrenocortical insufficiency of autoimmune or infectious etiology)
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Slow, progressive muscle weakness in boys
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Becker's muscular dystrophy (X-linked, defective dystrophin; less severe than Duchenne's)
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Small, irregular red spots on buccal/ lingual mucuosa with blue-white centers
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Koplik spots (measles)
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Smooth, flat, moist white lesions on genitals
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Condylomata lata (2°syphilis)
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Small, nontender, erythematous lesions on palms/soles
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Janeway lesions (infective endocarditis)
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Splinter hemorrhages in fingernails
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Bacterial endocarditis
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"Strawberry tongue"
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Scarlet fever, Kawasaki disease, toxic shock syndrome
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Streak ovaries, congential heart disease, horseshoe kidneys
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Turner's syndrome (XO, short stature, webbed neck, lymphedema)
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Sudden swollen/painful big toe joint, tophie
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Gout/podagra (hyperuricemia)
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Swollen gums, mucous bleeding, poor wound healing, spots on skin
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Scurvy (vitamin C deficiency: can't hydroxylate proline/lysine for collagen synthesis)
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Swollen, hard, painful finger joints
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Osteoarthritis (osteophytes on PIP [Bouchard's nodes], DIP [Heberden's nodes])
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Systolic ejection murmur (crescendo-decrescendo)
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Aortic valve stenosis
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Thyroid, parathyroid, adrenal tumors
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Sipple's syndrome (MEN 2A)
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Ulcerated genital lesion with exudate (painful)
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Chancroid (Haemophilus ducreyi)
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Unilateral facial drooping
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Bell's palsy (LMN CN VII palsy)
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Urethritis, conjunctivitis, arthritis in a male
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Reiter's syndrome (reactive arthritis associated with HLA-B27)
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Vascular birthmark (portwine stain)
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Hemangioma (benign, but associated with Sturge-Weber syndrome)
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Vasculitis from exposure to endotoxin causing glomerular thrombosis
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Shwartzman reaction (following second exposure to endotoxin)
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Vomiting blood following esophagogastric lacerations
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Mallory-Weiss syndrome (alcoholics and eating disorders)
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"Waxy" casts with very low urine flow
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Chronic end-stage renal disease
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WBC casts in urine
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Acute pyelonephritis
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Weight loss, diarrhea, arthritis, fever, adenopathy
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Whipple's disease (Tropheryma whippelii)
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"Worst headache of my life"
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Berry aneurysm (associated with adult polycystic kidney disease)
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