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23 Cards in this Set
- Front
- Back
PROTONIX(pantoprazole) MAY ALTER THESE Laboratory Values
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SGPT, creatinine increased, hypercholesterolemia, and hyperuricemia. transaminase elevations
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PROTONIX (pantoprazole), DRUG INTERACTIONS
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theophylline, cisapride, antipyrine, caffeine, carbamazepine, diazepam (and its active metabolite, desmethyldiazepam), diclofenac, naproxen, piroxicam, digoxin, ethanol, glyburide, an oral contraceptive (levonorgestrel/ethinyl estradiol), metoprolol, nifedipine, phenytoin, warfarin (see below), midazolam, clarithromycin, metronidazole, or amoxicillin
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PROTONIX (pantoprazole),
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Patients treated with proton pump inhibitors and warfarin concomitantly should be monitored for increases in INR and prothrombin time.
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PROTONIX (pantoprazole),
Serious Adverse Events |
include retinal detachment, iatrogenic traumatic cataract and endophthalmitis
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PROTONIX (pantoprazole),
Common Adverse Events |
Bronchitis, diarrhea, headache, dizziness, nausea
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PROTONIX (pantoprazole),
Common Adverse Events 6-10% |
6-10% Bronchitis, diarrhea, headache, dizziness, nausea
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PROTONIX (pantoprazole),
Common Adverse Events 1-5% |
Arthritis, chest pain, dyspepsia, hearing loss, vertigo, vomiting, contact dermatitis
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WHAT IS pantoprazole (Protonix) AND WHAT DOES IT DO?
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Proton Pump Inhibitor,
Total inhibition of gastric acid secretion |
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Proton Pump InhibitorS WHAT ARE SOME?
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lansoprazole Prevacid),omeprazole (Prilosec),rabeprazole (Aciphex),pantoprazole (Protonix),esomeprazole (Nexium)
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Proton Pump Inhibitors:
Therapeutic Uses ? |
GERD maintenance therapy
Erosive esophagitis Short-term treatment of active duodenal and benign gastric ulcers Zollinger-Ellison syndrome Treatment of H. pylori-induced ulcers |
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Proton Pump Inhibitors:
Nursing Implications ? |
Assess for allergies and history of liver disease, May increase serum levels of diazepam, phenytoin, and cause increased chance for bleeding with warfarin
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Angiotensin-Converting Enzyme Inhibitors
(ACE Inhibitors)? |
Large group of safe and effective drugs
Often used as first-line agents for CHF and hypertension May be combined with a thiazide diuretic or calcium channel blocker |
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ACE Inhibitors, Side Effects
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Fatigue Dizziness
Headache Mood changes Impaired NOTE: first-dose hypotensive effect may occurtaste |
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Name some ACE inhibitors
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Capoten/Captopril, Vasotec/Enalapril, Lotensin/Benzapril
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What does an ACE inhibitor do?
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Lowers periperal vascular resistance without increasing cardiac output, cardiac rate and cardiac contractility
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Name some Beta Blockers
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Inderal/Propranolol, Tenormin/Atenolol, Lopressor/Metroprolol
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Opioid Analgesics (ei:MORPHINE): Side Effects
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Euphoria
Nausea and vomiting Respiratory depression Urinary retention Diaphoresis and flushing Pupil constriction (miosis) Constipation |
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Opioid Analgesics:
Nursing Implications |
Oral forms should be taken with food to minimize gastric upset.
Ensure safety measures, such as keeping side rails up, to prevent injury. Withhold dose and contact physician if there is a decline in the patient’s condition or if VS are abnormal—especially if respiratory rate is below 12 breaths/minute. |
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Opioid Analgesics:
Nursing Implications |
Constipation is a common side effect and
may be prevented with adequate fluid and fiber intake. orthostatic hypotension. |
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Opioid Analgesics:
Nursing Implications |
Should VS change, patient’s condition decline,
or pain continue, contact physician immediately. Respiratory depression may be manifested by respiratory rate of less than 12/min, dyspnea, diminished breath sounds, or shallow breathing. |
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Heparin Route and Dosage
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Bolus dose: 5000units I.V., then 20-40 thousand units continuously
Prophylaxis of embolism: 5000 units s.q. every 12 hrs. Contraindicated in persons with active bleeding |
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Heparin: adverse reactions
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Spontaneous bleeding
Injection site reactions Hypersensitivity reactions |
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Heparin: Nursing Implications
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Must be given on time.
S.Q. route: 25 guage needle, apply pressure, no massage Patient has to be weaned off continuous infusion Oral anticoagulant started 3-5 days before I.V. infusion discontinued. |