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31 Cards in this Set
- Front
- Back
Thyrotropin-releasing hormone
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(TRH)
Hypothalamus Peptide Phospholipase C (IP3/Ca++) Stim secretion of TSH & Prolactin |
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Corticotropin-releasing hormone
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(CRH)
Hypothalamus Peptide Adenylyl Cyclase (cAMP) Stim Secretion of ACTH |
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Gonadotropin-releasing hormone
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(GnRH)
Hypothalamus Peptide Phospholipase C (IP3/Ca++) Stim secretion LH & FSH |
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Somatostatin or Somatotropin release-inhibiting hormone
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(SRIF)
Hypothalamus Peptide Inhibits secretion of GH |
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Dopamine or Prolactin-inhibiting factor
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(PIF)
Amine Hypothalamus Inhibits secretion of prolactin |
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Growth-hormone-releasing hormone
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(GHRH)
Peptide Phospholipase C (IP3/Ca++) Hypothalamus Stim secretion of GH |
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Thyroid-Stimulating Hormone
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(TSH)
Peptide Ant. Pit. Adenylyl Cyclase (cAMP) Stim synthesis & secretion of thyroid hormones |
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Follicle-stimulating hormone
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(FSH)
Peptide Ant. Pit. Adenylyl Cyclase (cAMP) 1. Stimulates sperme maturation in the sertoli cells of the testes 2. Stimulates follicular development & estrogen synth in ovaries |
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Luteninizing hormone
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(LH)
Peptide Ant. Pit. Adenylyl Cyclase (cAMP) 1. Stimulates testosterone synth in the leydig cells of the testes 2. Stimulates ovulation, formation of the corpus luteum, estrogen & progesterone synth in the ovaries |
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Growth Hormone
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(HGH)
Peptide Ant. Pit. Stim protein synth &overal growth |
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Prolactin
|
peptide
Ant. Pit. Stimulates milk production & secretion in breast |
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Adrenocorticotropic homone
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(ACTH)
Peptide Ant. Pit. Adenylyl Cyclase (cAMP) Stim synth & secretion of adrenal cortical hormones (cortisol, androgens, & aldosterone) |
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Melanocyte-stimulating hormone
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(MSH)
Peptide Adenylyl Cyclase (cAMP) Ant. Pit. Stimulates melanin synthesis (? humans) |
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Oxytocin
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Peptide
Post. Pit. Phospholipase C (IP3/Ca++) Stim milk ejection from the breasts & uterine contractions |
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Vasopressin or Antidiuretic hormone
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(ADH)
Peptide Post. Pit. V1 Receptor: Phospholipase C (IP3/Ca++) V2 Receptor: Adenylyl Cyclase (cAMP) Stimulates H2O absorption in principal cells of collecting ducts & constriction of arterioles |
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Triiodothyronine (T3) & L-thyroxine (T4)
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Amine
Thyroid Stimulates skeletal grouth; oxygen consumption; heat production; protein, fat, and carbohydrate utilization; perinatal maturation of the CNS |
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Calcitonin
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Peptide
Adenylyl Cyclase (cAMP) Thyroid Decreases serum Ca++ |
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Parathyroid hormone
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(PTH)
parathyroid peptide Adenylyl Cyclase (cAMP) increases serum Ca++ |
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Cortisol (glucocorticoid)
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Steroid
Adrenal Cortex Stim gluconeogenesis; inhibits inflammatory response; suppresses immune response; enhances vascular responsiveness to catecholamines |
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Aldosterone (mineralcorticoid)
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Steroid
Adrenal Cortex Increases renal NA reabsorption, K secretion, and H secretion |
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Dehydroepiandrosterone (DHEA) & Androstenedione (adrenal androgens)
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Steroid
Adrenal Cortex Stimulates spermatogenesis; stimulates male secondary sen characteristics |
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Testosterone
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Steroid
Testes Stimulates spermatogenesis; stimulates male secondary sen characteristics |
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Estradiol
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Steroid
Ovaries (lesser degree corpus luteum) Stim growth & development of female reproductive system, follicular phase of menstrual cycle, development of breasts, prolactin secretion, maintains pregnancy |
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Progesterone
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Steroid
Ovaries (lesser degree corpus luteum) Stim luteal phase of menstrual cycle, maintains pregnancy |
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Human Chorionic gonadotropin
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(HCG)
Peptide Adenylyl Cyclase (cAMP) Placenta stim estrogen & progesterone synth in corpus luteum of early pregnancy |
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Human placental lactogen (HPL) or Human chorionic somatomammotropin
|
Peptide
has GH-like and prolactin-like actions during pregnancy |
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Insulin
|
peptide
Tyrosine Kinase Mech. pancreas Beta cells decreases blood [glucose] |
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Glucagon
|
peptide
Adenylyl Cyclase (cAMP) pancreas alpha cells increases blood [glucose] |
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Renin
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Kidney
Peptide catalyzes conversion of angiotensinogen to ang I |
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1, 25- Dihydroxycholecalciferol
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Steroid
Kidney Increases intestinal adbsorption of Ca++, Bone mineralization |
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Norepinephrine, epiepherine
|
amine
adrenal medulla actions of the sympathetic nervous system. |