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425 Cards in this Set
- Front
- Back
Two beta blockers approved for treatment of heart failure
|
Metoprolol succinate and carvedilol
|
|
This class of antiarrythmic drug decreases mortality in CHF patients
|
Beta blockers
|
|
EKG often shows an usual RBBB in this genetic syndrome that predisposes to sudden cardiac death
|
Brugada syndrome
|
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It is what CRT-D stands for
|
Cardiac Resynchronization therapy Defibrillator
|
|
The epsilon wave has been classically decried in patients with this congenital syndrome
|
Arrhymogenic right ventricular dysplasia
|
|
This is the number needed to treat with a relative risk reduction of 50% and absolute risk reduction of 12.5 %
|
8
***(1/Absolute Risk Reduction) |
|
Using a normal albumin as 4, this is the corrected calcium for a serum Calcium of 7.4 and albumin of 2
|
9
***Corrected Calcium = (0.8 * (Normal Albumin - Pt's Albumin)) + Serum Ca |
|
This is the LDL cholesterol in a patient with total cholesterol of 190, HDL of 90 and TG of 50
|
90
****Friedewald (1972) Formula: LDL = TC - HDL - TG/5.0 |
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Positive liklihood ratio with a sensitivity of 0.8 and a specificity of 0.2
|
1
*****Positive Likelihood Ratio= (sensitivity)/(1-specificity) |
|
Stool osmotic gap with a stool osmolality of 300, stool sodium of 20 and potassium of 80
|
100
****300(or stool osmolality) − 2 *(stool Na + stool K) >100 suggests osmotic (celiac, lactase deficiency, chronic pancreatitis |
|
Eponymous name for antiphospholipid syndrome
|
Hughes syndrome
|
|
Testing for antiphospholipid syndrome includes lupus anticoagulant and these two antibodies
|
Beta-2 microglobulin and anticardiolipin antibodies
|
|
It is the eponymous name for CAPS (catastrophic antiphospholipid syndrome)
|
Asherson's syndrome
|
|
Name of classification for APS
|
Modified/updated sapporo
|
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The association of antiphospholipid antibodies with livedo reticularis and recurrent strokes is known as this
|
Sneddon's syndrome
|
|
Drug used to cause muscle relaxation in neuroleptic malignant syndrome
|
Dantrolene
|
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Hydrochlorothiazide plus triamterene
|
Diazide
|
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Anti-thrombin inhibitor thats begins with "D"
|
Dabigitran
|
|
Drug that beings with "D" and is an anti-thrombin inhibitor
|
Dabigatran (Pradaxa)
|
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Drug starting in "D" that may cause elevated CPK and is inhibited by surfactant
|
Daptomycin
|
|
Drug starting with "D" that is a class III antiarrythmic
|
Dofetilide
|
|
This form of warfarin is most potent
|
S- warfarin
|
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Factor Xa inhibitor recently shown to be non-inferior to warfarin in stroke prevention in atrial fibrillation
|
Rivaroxaban
|
|
This gene plays an important roe in metabolizing s-warfarin to its inactive form
|
CYP2C9
|
|
This gene is important in the production of active warfarin
|
VKORC1
|
|
It is was "WARF" in warfarin stands for
|
Wisconsin Alumni Research Foundation
|
|
Esophagitis in HIV with multinucleated giant cells on histology
|
HSV
|
|
This virus has been associated with multicentric castlema disease in HIV patients
|
HHV-8
|
|
Steroids added to PCP treatment in these two situations
|
pa02 <70 or A-a gradients >35
|
|
Test that must be don before starting maraviroc
|
viral tropism assay
|
|
Screening test for hypersensitivity to abacavir
|
HLA B-5701
|
|
Name of syndrome associated with hypokalemic periodic paralysis and long QT7
|
Anderson-Tawil Syndrome
|
|
The CAM score used for estimation of severity of malaria stands for this
|
Coma Acidosis Malaria
|
|
Drug very active against falciparum believed to produce free radicals in the parasite food vacuole
|
Artesunate, artemisinins
|
|
Malaria may be cause by pasmodium vivax, malriae, falciparum and these two others
|
Ovale and knowlesi
|
|
Malarone is a combination of atovaquone and this drug
|
Proguanil
|
|
CAM score uses bicarbonate score, respiratory rate score and these two factors
|
Base deficit and GSC
|
|
Polyglandular syndrome 1 include hypoparathyroidism, addison's disease and this
|
Mucocutaneous candidiasis
|
|
Terbinafine inhibits this enzyme
|
Squalene epoxidase
|
|
Caspofungin and micafungin belong to this class of drugs
|
Echinocandins
|
|
Hyper IgE sydrome associated with mucocutaneous candidiasis
|
Job syndrome
|
|
Candida species with strong affinity for plastic that has a shaggy, spider-like appearance on sabouraud's agar
|
Candida parapsilosis
|
|
Syndrome of Cafe Au lait spots, polyostotic fibrous dysplasia and endocrine dysfunction
|
McCune-Albright syndrome
|
|
Acromegaly like condition where patients have normal IGF-1 and insulin resistance
|
Pseudoacromegaly
|
|
Drug used to inhibit growth hormone
|
Pegvisomant
|
|
Three components of MEN IIA Sydrome
|
Medullary thyroid cancer, Pheochromocytoma, Hyperparathyroidism/Parathyroid hyperplasia
|
|
Drug starting in "R" was is used in treatment of Tumor Lysis Syndrome
|
Rasburicase
|
|
Drug starting with "R" that is an integrase inhibitor (anti-viral medication developed for use in HIV)
|
Raltegravir
|
|
Drug starting in "R" used in treatment of Alzheimer's disease
|
Rivastigmine
|
|
Drug starting in "R" that is a SERM
|
Raloxifene
|
|
Sildenalfil has been marketed for pulmonary hypertension as this brand name (begins with "R")
|
Revatio
|
|
Patients with hyperplastic polyps should be screened within this time
|
10 years
|
|
Other than Heme-Occult testing, these other two stool tests can be used in screening
|
Stool DNA and feval immuno-chemical testing (FIT)
|
|
Patients with sessile polyps removed piecemeal should have repeat colonoscopy within this time
|
6 months
|
|
Patients with 3-10 polyps should be screened after this many years
|
3 years
|
|
patients with >1cm adenoma or adenomas with villous features or high grade dysplasia should be screened within this time
|
3 years
|
|
Syndrome where jaundice results from erosion of a gallstone through the gallbladder wall, compressing the common hepatic duct
|
Mirizzi syndrome
|
|
Lead intoxication may lead to this type of gout
|
Saturnine
|
|
This vaccine has been used to prevent bladder cancer
|
BCG vaccine
|
|
Drug of choice for treatment of MDS with 5Q deletion
|
Lenalidomide
|
|
Aggrenox is comprised of 200mg dipyridamole and this much aspirin
|
25mg
|
|
Name of this syndroe is associated with hypokalemic periodic paralysis and long QT7
|
Anderson-Tawil syndrome
|
|
Stress fracture associated with CKD and normal PTH, caused by excess vitamin D intake
|
Adynamic bone disease
|
|
This type of RTA is associated with an alkaline urine PH
|
Type 1 -Distal
|
|
Drug used to decrease risk of uric acid stones
|
Potassium citrate
|
|
It is what CVVH stands for
|
Continuous venovenous hemofiltration
|
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Drug starting in "P" which when given in an aerosolized form can be used to PCP prophylaxis in HIV
|
Pentamidine
|
|
Drug beinnging with "P" that is part of four drug TB regimen
|
Pyrazinamide
|
|
Drug beginning with "P" used for treatment of Toxoplasmosis
|
Pyrimethamine
|
|
FDA approved in 2009 this statin goes by the brand name livalo
|
Pitastatin
|
|
Drug beginning with "P" that is growth hormone inhibitor
|
Pegvisomant
|
|
Only FDA approved drug for weight loss
|
Orlistat (Xenical)
|
|
Bisphosphonates inhibit the effect of osteoporosis treatment drug
|
Teriparatide
|
|
This drug is preferred over bromocriptine as the first ling treatment of prolactinomas
|
Cabergoline
|
|
Syndrome that occurs 7-10 days after neursurgical procedures presenting with hyponatremia and hypotension
|
Cerebral salt wasting
|
|
Lupus was derived from the latin word for this
|
Wolf
|
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Presence of these antibodies in a pregnant mother increased the risk of congenital complete heart block
|
Anti-Ro and Anti-La
|
|
Human Monoclonal antibody targeting RANK-L was FDA approved for osteoporosis in June 2010
|
Denosumab
|
|
Human monoclonal antibodies FDA approved in March 2011 for treatment of SLE
|
Belimumab
|
|
AML with DIC is associated with this translocation
|
t(15:17) all trans retinoic acid
|
|
Direct thrombin inhibitor used for HITT that is eliminated by the kidneys
|
Lepirudin
|
|
Two of three tyrosine kinase inhibitors approved for CML treatment
|
Imatinib, dasatinib, or nilotinib
|
|
Drug used to treat MDS associated with deletion of long arm of chromosome 5
|
Lenalidomide
|
|
Diagnosis of Creutzfeld Jakob disease by biopsy of brain or this
|
Tonsils
|
|
First line treatment for narcolepsy
|
Modafinil
|
|
Assessment for need of steroid in alcoholic hepatitis is determined by this blood test
|
Carbohydrate free transferrin
|
|
Treatment of scleroderma renal crisis in pregnancy
|
ACE-inhibitor
|
|
Protein that may be found in CSF of CJD
|
14-3-3 protein
|
|
Monoclonal antibody used in the treatment of paroxysmal nocturnal hemoglobinuria
|
Eculizimab
|
|
Acidosis in Type 2 RTA results from this
|
Decreased bicarbonate absorption
|
|
This type of renal tubular acidosis causes an alkaline urine PH
|
Type 1
|
|
Autoimmune diseases are likely to be associated with which type of RTA
|
Type 1
|
|
Use of TMP-SMX is likely to cause this type of RTA
|
Type 4
|
|
Calcium-Phospahte should be less than this
|
55
|
|
Sevalemer and lanthanum are both these types of drugs
|
Phosphate binders
|
|
Nephropathy associated with Hodgkin's lymphoma
|
Minimal change disease
|
|
Histological cause of renal artery stenosis in persons <40
|
Fibromuscular dysplasia
|
|
Cyst-like brown tumors secondary renal osteodystrophy
|
Osteititis cystica fibrosa, von recklinhausen's disease
|
|
Condition associated with intestinal bacterial overgrowth
|
Scleroderma
|
|
Two antibodies associated with autoimmune hepatitis
|
ANA, Smooth muscle, LKM, SLA
|
|
Extremely rare syndrome associated with mechanics hands, myositis, arthritis and interstitial lung disease
|
Antisynthetase syndrome
|
|
3 skin findings found in dermatomyositis
|
Gottron's papulres, shawl sign, heliotrope rash, erythroderma
|
|
Meltzer's triad of cryoglobulinemia comprises arthralgia, myalgia and this
|
Purpura
|
|
Obstruction of Meibomian tear gland
|
Chalazion
|
|
Disease associated with iris hamartomas and optic gliomas
|
Neurofibromatosis
|
|
Presence of this in wet age related macular degeneration differentiates it from dry
|
Neovascularization
|
|
Eye condition that has been associated with acute pancreatitis
|
Putcher's retinopathy
|
|
Damage to Meyer's loop of the right temporal lobe would lead to this visual defect
|
Left superior quadrant anopsia
|
|
Iodine induced hypothyroidism is referred to as this
|
Wolff-Chaikoff effect
|
|
Name for clubbing appearance of the fingers in Graves disease
|
Thyroid acropachy
|
|
Blunted symptoms of thyrotoxicosis in elderly
|
Apathetic hyperparathyroidism
|
|
Selective estrogen modulator (SERM) used in treatment of Reidel's thyroiditis
|
Tamoxifen
|
|
Sustained hand grip classically increases the intensity of this murmur
|
Mitral Valve Prolapse
|
|
This refers to the common finding of an apical murmur in a very elderly person who has aortic stenosis
|
Gallavardin phenomenom
|
|
Blow to the chest resulting in arrythmia and sudden cardiac death
|
Commotio cordis
|
|
Causes of pulsus alternans
|
Left ventricular dysfunctions
|
|
The recent re-ly trial showed that this drug was non-inferior to warfarin in preventing strokes in atrial fibrillation
|
Dabigatran
|
|
AML M5 classically associated with this
|
Gingival hyperplasia
|
|
A patient with CLL Stage III must have this
|
Anemia
|
|
Findings on flow cytometry in PNH
|
Decreased CD55 and CD 59
|
|
Common side effect of the multiple myeloma drug Bortezomib
|
Peripheral Neuropathy
|
|
Dementia associated with Visual Hallucinations
|
Lewy Body Dementia
|
|
Two drugs that can be used for treatment of of meningococal exposure
|
Rifampin and Ciprofloaccin
|
|
Electrical shock sown spine of bending beck forward in multiple sclerosis or cervical spondylosis
|
Lhermitte sign
|
|
CSF test used for Creutzfeldt-Jakob Disease
|
14-3-3
|
|
Recurrent Benign aseptic meningitis secondary to HSV
|
Mollaret's meningitits
|
|
Drug begninng with "E" used to treat rheumatoid arthritis
|
Etanercept or ENBREL
|
|
Drug beginning with "E" that is a an incretin mimetic
|
Exanitide
|
|
Drug beginning with "E" that is an HIV protease inhibitor
|
Efavirenz
|
|
Drugs beginning with "E" used to treat von willibrand's disease
|
Estrogen
|
|
Treatment beginning with "E" that is used for treatment of intravascular hemolysis in PNH
|
Eculizumab
|
|
Parasite associated with increased risk of bladder cancer
|
Schistosomiasis
|
|
Viral Load required in HIV to start HAART
|
>55,000
|
|
Bifid pulse is seen in these two conditions
|
HCM and Aortic Stenosis
|
|
Rapid X Descent
|
Tamponade
|
|
Blood supply for the AV node
|
RCA
|
|
Regular cannon A waves is seen in this condition
|
AVNRT/TS
|
|
Lab value which differentiates B12 deficiency from folate deficiency
|
MMA (methylmalonic acid)
|
|
Autoimmune hemolytic anemia + ITP
|
Evans syndrome
|
|
Gingivial Hyperplasia is seen with this type of leukemia
|
AML M5 (monocytic subtype
|
|
Lab value which differentiates B12 deficiency from folate deficiency
|
MMA (methylmalonic acid)
|
|
Cigar/Pencil shaped RBC is seen on PS in this condition
|
Iron Deficiency
|
|
Genetic cause of SCD with RBBB and ST Elevation in V1-V3
|
Brugada syndrome
|
|
Lab value which differentiates B12 deficiency from folate deficiency
|
MMA (methylmalonic acid)
|
|
Cigar/Pencil shaped RBC is seen on PS in this condition
|
Iron Deficiency
|
|
Factor Deficiency seen in amyloidosis
|
Factor X
|
|
Commonest cause of deaht in rheumatoid arthritis
|
Coronary Artery Disease
|
|
Mixed connective tissue diseases is a mix of these three
|
SLE, polymyositis, and systemic sclerosis
|
|
2 diseases commonly associated with pseudo gout
|
Hemochromatosis and hyper parathyroidism
|
|
DMARD with similar action and S/E profile with methotrexate
|
Leflunomide
|
|
This type of vasculitis causes HTN secondary to RAS
|
Takayasu arteritis
|
|
Hepatitis B can be treated with Lamivudine and this drug
|
Tenofovir, adefovir, entecavir
|
|
Xanthine oxidase inhibitor other than allopurinol
|
Febuxostat
|
|
Colchicine was FDA approved treatment of gout in this year
|
2009
|
|
Numbness and pain in 3rd and 4th metatarsals secondary to this benign neuroma
|
Morton's Neuroma
|
|
C-ANCA immunoflourescene pattern is commonly associated with antibodies to this
|
Proteinase-3
|
|
Audible click on pressing two metatarsal heads together in morton's neuroma is known as this sign
|
Mulder's sign
|
|
PAS positive macrophages on intestinal biopsy
|
Whipple's disease
|
|
Organism associated with undercooked pork that can result in severe diarrheal syndrome
|
Yersinia enterolitica
|
|
Gene and chromosome associated with familial adenomatous polyposis
|
APC gene on long arm of chromosome 5
|
|
Erosion of large tortuous arteriole in stomach
|
Dieulafoy's lesion
|
|
Hyperplastic hypersecretory gastropathy presenting with postprandial pain and albumin loss
|
Menetrier's disease
|
|
What is winter's formula
|
PC02= 1.5(HC03) +8 +/- 2
|
|
Ingestion of this can cause ketonemia without acidosis
|
Isopropyl alcohol
|
|
Indications for steroids in PCP infection
|
paO2 < 70 or A-a gradients >35
|
|
Formula for alveolar P02
|
(Fi02 x713) - (PaCO2 x1.2)
|
|
Suboxone is a combination of buprenorphine and this drug
|
Naloxone
|
|
Beta-blocker starting with "N" with powerful vasodilatory effect
|
Nebivolol
|
|
Insulin secretagogue marketed as starlix
|
Nateglinide
|
|
Drug starting with "N" used to treat multiple sclerosis
|
Natalizumab
|
|
Treatment of Philadelphia chromosome positive CMP
|
Nilotinib
|
|
Topical cream used in treatment of genital warts
|
Podophyllin or imiquimod
|
|
Esophageal biopsy in HIV showing owl's eye inclusions
|
CMV esophagitis
|
|
Cause of diarrhea occurring while patient on cruise ship
|
Norwalk virus
|
|
This antiviral agent used for treatment of influenza may cause bronchospasm
|
Zanamivir
|
|
Formula for non-LDL cholesterol
|
Total cholesterol - HDL
|
|
Lipid lowering drug indicated for treatment of diabetes
|
Colesevelam
|
|
Omega 3 Fatty Acids reduce triglycerides but increase in lipoprotein
|
LDL
|
|
Lipid lowering drug that decreased insulin sensitivity
|
Niacin
|
|
In the Friedewald equation, VLDL is equal to this
|
Triglycerides divided by 5
|
|
Syndrome characterized by finger agnosia and dyscalcula
|
Gerstman syndrome
|
|
Name of maneuver used to reverse benign positional vertigo
|
Epley's maneuver
|
|
Inflammatory disease similar to multiple sclerosis causing episodic optic neuritis and myelitis
|
Neuromyelitis optica (NMO) or Devic's disease
|
|
FDA approved in 2010 this drug improves walking in multiple sclerosis
|
Fampridiine SR (AMPYRA)
|
|
This stage of sleep involves sleep spindles and K complexes
|
Stage 2
|
|
Positive liklihood ratio with a sensitivity of 0.8 and specificity of 0.6
|
2
|
|
Centor criteria include fever, absence of cough and these two
|
Tonsillar exudate, tender cervical lypmhadenopathy
|
|
Eponymous name for uveoparotid syndrome in sarcoidosis
|
Heerfordt's syndrome
|
|
Blood pressure greater in legs vs arms in aortic regurgitation known as this sign
|
Hill sign
|
|
Blue toes post-angiography secondary to this
|
cholesterol emoblism
|
|
EGFR inhibitor used in treatment of k-ras wild-type colorectal cancer
|
Cetuximab
|
|
Drug starting with "F" that is a xanthine oxidase inhibitor
|
Febuxostat
|
|
Treatment for CLL
|
Fludarabine
|
|
Drug used as antidote for ethylene glycol intoxication
|
Fomepizole
|
|
Drug starting with "F" ndicated in hypertensive emergency
|
Fenoldopam
|
|
Antiandrogen drug beginning with "F" used to treat prostate cancer
|
Flutamide
|
|
Multiple myleoma drug that increases risk of DVT
|
Thalidomide
|
|
White blood cell with bi-lobed Dumbbell
|
Pelger-Huet cell
|
|
Activated protein C used in treatment of sepsis also called this
|
Drotecogin alfa
|
|
Management of persons exposed hepatitis
|
Hepatitis A immunoglobuliin
|
|
Other than neomycin this antibiotic is approved for treatment and prevention of hepatic encephalopathy
|
Rifaximin
|
|
Reynold's pentad for septic ascending cholangitis includes fever, abdominal pain, jaundice and these two
|
Hypotension and altered mental status
|
|
Type of recurrent cholangitis occuring in southeast asia
|
Oriental cholangitis
|
|
Cholangiocarcinoma at junction between left and right hepatic ducts
|
Klatskin tumor
|
|
Rare syndrome assocaited with mechanic's hands, myositis, arthritis and interstitial lung disease
|
Antisynthetase syndrome
|
|
Mcmurray test positive with this injury to this part of the knee
|
medical meniscus
|
|
Lachman's test positive with damage to this part of the knee
|
Anterior Cruciate ligament
|
|
Arthritis mutilans is classically associated with this type of arthritis
|
Psoriatic arthritis
|
|
HLA-B5701 screening should be done to present hypersensitivity to this drug
|
Abacavir
|
|
This HIV drug has been notorius for causing nightmares
|
Efavirenz
|
|
The protuberant crixivan belly associated with HIV lipodystrophy was named after the brand name for this drug
|
Indinavir
|
|
Atripla is a combination of emtracitabine and these two medications
|
Efavirenz and tenofovir
|
|
It is what the "I" in folfiri stands for in relation to treatment of colorectal cancer
|
Irinotecan
|
|
Most common cause of heel pain
|
Plantar fascitis
|
|
Autoantibody associated with absence of interstitial lung disease in patients with scleroderma
|
Anti-centromere antibody
|
|
Autoantibody assocaited with mixed connective tissue disease
|
Anti-U1-RNP
|
|
Autoantibody associated with myositis, interstitial lung disease, arthritis and a hyperkeratotic rash on the hands
|
antihistidyl-tRNA synthetase
|
|
Name four of the five major jones criteria for the diagnosis of rheumatic fever
|
Carditis,sydenham's chorea, polyarthrititis, EM, SC nodules
|
|
Watery diarrhea, hypokalemia, achlorhydria, and acidosis
|
VIPoma
|
|
Commonest cause of adrenal insufficiency
|
Iatrogenic glucocorticoids
|
|
Production is increased in sarcoidosis and contributes to hypercalcemia
|
1,25-dihydroxycholecalciferol
|
|
This drug stimulates new bone formation by increasing osteoblast activity
|
Teriparatide or Recombinant human PTH
|
|
Internuclear opthalmoplegia is a lesion of this structure
|
Medical longitudinal fasiculus
|
|
The classic findings in Wernicke's encephalopathy
|
Confusion, ataxia, ophthalmoplegia
|
|
Acute onset of ipsalateral horner's syndrome, ipsalateral face and contralateral body sensory deficit
|
Wallenberg's syndrome
|
|
The other name of relative afferent pupillary defect
|
Marcus-Gunn pupil
|
|
Syndrome characterized by frequent falls and vertical gaze paralysis
|
Progressive supranuclear palsy
|
|
The commonest glomerulonephritis in the world
|
IgA nephropathy
|
|
Syndrome characterized by joint pain, abdominal pain, palpable purpura and nephritic sediment
|
Henoch-Scholein purpura
|
|
In addition to RBC casts, this microscopic finding supports diagnosis of glomerulonephritis
|
Dysmorphic RBC
|
|
This hematological lab finding in CKD is an independent risk predictor of LVH
|
Anemia
|
|
This syndrome is caused by inactiving mutation of loop diuretic sensitive channel in the kidney
|
Bartter's syndrome
|
|
This substance is a major health hazard for children in old house
|
Lead
|
|
Medical treatment for mild to moderate salicylate intoxication
|
Urinary alkalinization
|
|
Antidote for calcium channel blocker toxicity
|
Calcium
|
|
EtOH poisoning associated with increased osmolar gap but a normal anion gap
|
Isopropyl alcohol
|
|
Drug for nerve gas exposure that reactivates acetylcholine esterase
|
Pralidoxime
|
|
Mention at least 2 auscultatory findings associated with acute disappears with relief of ischemia
|
Murmur of MR, S4, S3, paradoxical S2 splitting
|
|
Dermatologic condition associated with celiac disease
|
Dermatitis herpetiformis
|
|
Inhaled drug effective for bronchoconstriction due to propanolol
|
Ipratoprium
|
|
+Kveim-siltzbach test occurs in this disease
|
Sarcoidosis
|
|
This medication inhibits the common pathway of platelet aggregation
|
Abciximab, Tirofiban, Eptifibatide
|
|
Infection with this parasite can cause portal hypertension
|
Schistosoma mansoni
|
|
Organism associated with chronic diarrhea and eosinophilia in AIDS patients
|
Isospora belli
|
|
Fever, flu-like symptoms, tachycardia and hypotension developing during treatment of syphilis
|
Jarisch-Herxheimer reaction
|
|
The other name of type 2 lepra reaction
|
Erythema nodusum leprosum
|
|
Class of this drugs useful in the treatment of influenza A and B infection
|
Neuraminidase inhibitor
|
|
The single most important prognostic marker for multiple myeloma
|
B2-microglobulin
|
|
Combination of autoimmune hemolytic anemia and ITP
|
Evan's syndrome
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A coagulation factor deficiency A coagulation factor deficiency with increased PTT< normal PT, thrombin time, platelet count, bleeding time and no clinical bleeding
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Factor XII deficiency
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Coumadin induced skin necrosis occurs in this disorder
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Protein C or S deficiency
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Severe bleeding with normal PT, PTT, thrombin time, platelet count and bleeding time
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Factor XIII deficiency
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Pulmonary artery occlusion pressure estimates this parameter
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LVEDP
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Name the components of the tetralogy of Fallot
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RV outflow obstruction, VSD, RVH, aortic override of VSD
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LV EF and systolic LV internal diameter used as an indication for surgical intervention in severe mitral regurgitation
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LVEF <60%
LVID in systole >45 mm |
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Diagnosis associated with equalization of diastolic pressures in RA, RV, PCWP, and LV
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Tamponade or constrictive pericarditis
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Blue sclera, hearing impairment and brittle bones
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Osteogenesis imperfecta
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Inherited disorder with HTN, hypokalemia, alkalosis
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Liddle's syndrome
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Acidosis, aminoaciduria, phosphaturia and glycosuria
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Fanconi's syndrome
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Gastrointestinal polyps and pigmented macules around mouth and lips
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Peutz-jeghers' syndrome
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Hypogonadic gonadism, anosmia, and color blindness
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Kallman syndrome
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This cancer isa ssociated with overproduction of calcitonin
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Medullary carcinoma of the thyroid
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Most common malignancy in humans
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Skin cancers
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A relapsing rever associated with hodgkin's disease
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Pel-ebstein fever
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Test used to screen for anal intraepithelial neoplasia in high risk individuals
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Anal pap smear
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A patient with SCLC presenting with subacute onset of confusion memory loss and temporal lobe seizures
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limbic encephalitis
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Infertility, dextrocardia, recurrent respiratory infection
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Kartagner's syndrome
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Treatment of choice for Paget's diseases
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Bisphosphonates
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HSV disease with LMN facial palsy and vesicles in external ear
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Ramsay-Hunt syndrome
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An oral medication approved in 2009 for hypervolumic and euvolemic hyponatremia
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Tolvaptan/Samca
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Syndrome of digital clubbing and chronic proliferative periostitis of long bones seen in lung cancer
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Pulmonary hyperthrophic osteoarthropathy
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First person to see an RBC under a microscope
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Anton von Leewenhoek
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Other than imatinib and dasatinib this tyrosine kinase inhibitor can also be used in treatment of CML
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nilotinib
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Two blood tests used in diagnosis of heparin- induced thrombocytopenia
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Anti-platelet factor 4 and serotonin release assay
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Stage IV CLL may have anemia, lymphadenopathy ad HSP but must have this
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Thrombocytopenia
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Proteosome inhibitor used in treatment of multiple myeloma
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Bortezomib
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Von-willebrand's factor cleaving protease that is often inhibited
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ADAMTS-13
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This condition may result form gadolinium administration in patient with impaired renal function
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Nephrogenic systemic sclerosis
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Urine anion gap in renal tubular acidosis in this
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Positive
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Valvular defect common in polycystic kidney disease
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Mitral valve prolapse
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Two drugs used in treatment of Wegener's granulomatosis
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Cyclophosphamide and steroids
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This bacterial cause of pneumonia has been associated with stevens-johnsons syndrome
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Mycoplasma pnuemoniae
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Black pleural effusion
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Aspergilosis nigricans
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The antibiotic for treatment of VRE is inhibited by surfactant and should not be used to treat pneumonia
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Daptomycin
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The brand-name for the drug advair comprises these two drugs
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Salmeterol and fluticason
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Other than TMP-SMX two other drugs that can used as PCP prophylaxis in HIV patients
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atovaquone, dapsone, aerosol pentamidine
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Two main serological tests for celiac disease
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anti-endomysial and anti-tissue transglutaminase antibody
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Two serological tests used to diagnose pernicious anemia
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Anti-parietal cell and anti-intrinsic factor
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Posterior uveitis is associated with this malabsorption syndrome
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Whipple's disease
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Drug used to treat dermatitis herpetiformis
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Dapsone
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Pendular oscillations of the eyes with simultaneous masticatory contraction in Whipple's disease
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Oculomasticatory myorrhythmia
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Urate crystals appear this color when parallel to polarized light
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Yellow
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Ulnar deviation of the fingers resembling rheumatoid arthritis seen in SLE
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Jaccoud's arthropathy
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Use of this drug in psoriatic arthritis may actaully worsen psoriatic rash
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Hydroxychloroquine
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p-anca immunofluorescene pattern is commonly associated with antibodies to this
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Myeloperoxidase
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Syndrome of rheumatoid arthritis with pneumoconiosis
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Caplan's syndrome
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Coccidiodes immitis has been associated with this rash
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Erythema nodosom
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This virus has been associated with Kaposi sarcoma
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HHV-8
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First person to see RBC with a microscope
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Anthony Van Leewenhoek
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Seizures starting with laughter are referred to as this type of epilepsy
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Gelastic epilepsy
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Raising arms above head in SVC syndrome causing facial flushing is known as this sign
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Pemberton's sign
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Management of small cell cancer does not involve this
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Surgery
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Two chemotherapeutic drugs usually used for small cell cancer
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Paclitaxel and etoposide
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Polyuria and polydipsia commonly associated with this type of lung cancer
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Squamous cell cancer
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Contralateral flushing and hypohidrosis of the face in horner's syndrome
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Harlequin's sign
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Mixed metabolic acidosis and respiratory alkalosis with tinnitus
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Aspirin - salicylates
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Drug used for reversal of benzodiazepine overdose
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Flumazenil
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Treatment for methemoglobinemia
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Methylene blue
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Papilledema and retinal hemorrhages
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Methanol poisoning
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One test that will help distinguish intravacular hemolysis from extravascular hemolysis
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Low haptoglobin
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Presence of this feature on CBC represents the worst prognosis in patients with CLL
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Thrombocytopenia
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Feared bone complication of zoledronic acid use
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Osteonecrosis of the Jaw
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Hyposplenism or asplenia may cause the appearance of these on peripheral blood smear
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Howell-Jolly bodies
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Formula for number needed to treat
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1/Absolute Risk Reduction
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Formula for power if given beta error
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Power = 1- beta
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Definition of alpha error
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Prob of rejecting null hypothesis when it is true
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Formula for positive likelihood ratio
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Sensitivity divided by (1-specificity)
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Formula for negative likelihood ratio
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(1-sensitivity) divided by specificity
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Antiseizure Drug beginning with "C" associated with agranulocytosis and SIADH
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Carbmazepine
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Drug beginning with "C" that is a bile acid sequestrant is also used for glycemic control in diabetics
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Colesevelam
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This polymyxin antibiotic is used to treat MDR organisms such a P aeruginosa and Klebsiella
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Colistin
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This D-test is used to detect whether MRSA is truly susceptible to this antibiotic
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Clindamycin
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Treatment for CMV
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Retinitis
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Reversible apical hypokinesis secondary to stressful event
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Takotsubo cardiomyopathy- broken heart syndrome
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Thienopyridine approved in 2009 for treatment of ACS in patients planned for PCI
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Prasugrel
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Anti-arrythmic drug that may cause cinchonism
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Quinidine
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Brugada syndrome and ARVD are associated with an increased risk of this
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V-fib, Sudden cardiac death
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Most antiarrythmics are considered proarrythmic becuase they increase the risk of this
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Prolonged QT Torsades de pointes
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Treatment of first degree AV block in Lyme disease
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Doxycycline or amoxicillin
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Treatment of complete AV block
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Ceftriaxone or Pen G 14-21 Days
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Treatment of neurological manifestations
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IV ceftriaxone, Pen G or doxycycline x 14 days
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Treatment of Bell's Palsy in Lyme's disease
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Doxycycline or amoxicillin
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Stage 3 Lyme disease skin condition to due to untreated erythema migrans
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Acrodermatitis chronica atrophicans
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Drug starting with "V" that is an angiotensin receptor blocker
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Valsartan
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Drug starting with "V" that is used to treat bipolar disorder
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Valproic acid
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Drug that starts with a "V" that is used to treat herpes
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Valacyclovir
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Drug that starts with a "V" that is a smoking cessation drug
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Varenicline
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Drug that begins with "V" that is used to treat invasive aspergillosis
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Voriconazole
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This is the most common hereditary coagulation disorder in humans
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von Willebrand's disease
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No change in PT or PTT after mixing study
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Presence of factor inhibitor
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Factor deficiency not associated with excess hemorrhage but associated with prolonged PTT
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Factor XII (Hageman factor) deficiency
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No spontaneous bleeding and normal coagulation profile but often discovered after trauma
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Factor XIII deficiency
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Fibrinogen activity can be assessed using this measurement particularly when there is heparin on board
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Reptilase
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This NNRTI has been associated with birth defects when used during pregnancy
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Efavirenz
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CCR5 inhibitor
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Maraviroc - Seizentry
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Increased cardiovascular risk was demonstrated with the use of this NRTI in the smart study
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Abacavir
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Before starting abacavir patients be screened for this HLA subtype to prevent hypersensitivity
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B5701
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Involuntary lifting of the legs when lifting patients head off bed
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Brudzinki's sign
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Class of drugs associated with aseptic meningitis
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NSAID's, IV immunoglobulins
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Recurrent aseptic meningitis associated with HSV 2
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Mollaret's meningitis
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Post-exposure prophylaxis for meningitis with rifampin or this drug
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Ciprofloxacin
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CSF showing eosinophils in patient eating undercooked snails in a tropical country
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Angiostrongylus cantonensis
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Drug associated with lactic acidosis
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Linezolid
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This drug that is similar to tetracycline used to treat VRE
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Tigecycline
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Not recommended for VRE pneumonia as it is inhibited by surfactant
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Daptomycin
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Hyperreflexia and tremor associated with interaction between SSRI's and this VRE drug
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Linezolid
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Quinopristin and Dalfopristin are not effective for this type of VRE
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E Fecalis
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Anticoagulant used in the treatment of veno occlusive disease of the liver
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Defibrotide
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Cut off value for +PPD for you and me
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>=10mm
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HAART with s/e of hyperbilirubinemia
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Atazanavir
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1st line treatment for aspergillosis
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Voriconzale
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Treatment of babesiosis
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Quinine-clindamycin/atovaquone
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This virus causes spastic paralysis
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HTLV-1
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Egg shell calcification on chest x-ray
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silicosis
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Common cause of pneumonia in patients with CF
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Psuedomonas
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Criteria for ARDS
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P02/Fi02 <200, BL infiltrates, NL PCWP
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Photographic negative of pulmonary edema on chest X-ray
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Chronic eosinophillic pneumonia
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Egg shell calcification on chest xray
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Silicosis
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Short acting beta blocker that started with "E" used in hypertensive emergency
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Esmolol
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Drug with mortality benefit post MI CHF that begins with "E"
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Epleronone
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Drug for treatment of PNH that begins with "E"
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Eculizumab/ anti C5 antibody
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Novel drug for treatment of refractory ITP
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Eltrombopag
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Anticoagulant drug used in treatment of veno occlusive disease of the liver
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Defibrotide
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Serological biomarker that can be positive in Crohns disease
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ASCA
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Organisms with cause AIDS cholangiopathy
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Cryptosporidium and CMV
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This condition gives false negative testing in celiac disease
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IgA deficiency
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Diagnostic test for lactose intolerance
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Hydrogen breath test
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2 important contraindications for TIPS
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CHF and encephalopathy
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Hypovolemic hypoosmolar hyponatremia in patients s/p neurosurgical procedures
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Cerebral salt wasting
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RTA with urine pH >5.5 and hypokalemia
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Distal/Type 1 RTA
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Best ace drug for treatment of scleroderma renal crisis
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Captopril
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Drug used in treatment of resistant hypertension
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Spironolactone
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Treatment of myeloma kidney
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Chemotherapy and plasmapheresis
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Diagnostic aid for avascular necrosis in a patient with a pacemaker
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Radionuclide bone scan
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Commonest cause of osteoporosis in males
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Hypogonadism
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Formular for NNT and ARR
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NNT=1/ARR, ARR=LE-LP
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Two antidepressant with no weight gain side effects
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Buproprion and venlafaxine
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Treatment of acute unilateral hearing loss
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Steroids
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Cause for recurrent erythema multiforme
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HSV
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Drug used to prevent cyclophosphamide induced hemorhaddic cystitis
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Mesna
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Antidote for viagra toxicity
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Methylene blue
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Normal cup/disc ratio on fundoscopy
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<0.5
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Treatment of high altitude cerebral edema
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Dexmethasone
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Treatment of mild alzheimer dementia
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Donepezil
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Tx for pseudo tumor cerebri
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Acetazolamide
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Severe orthostatic hypotension with ataxia and Parkinsonism
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Shy-Drager syndrome/multiple system atrophy
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Recurrent episodes of myelitis, optic neuritis without brain lesions on MRI
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NMO, Devic's disease
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Acute onset unilateral headache with C/F of Horner syndrome
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Carotid artery dissection
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Drug beginning with "P" that is used for treatment of essential tremor
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Propanolol or primidone
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Drug beginning with "P" that is treatment of restless leg syndrome
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Pramipexole
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Antiplatelet drug with faster and better inhibition that clopidogrel used in ACS
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Prasugrel
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Drug beginning with "P" which causes total body alopecia and bradyarrhthmia
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Paclitaxel
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#1 cause of adrenal insufficiency worldwide
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Tuberculosis
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The association between thyroid disease and adrenal insufficiency +/- type 1 diabetes is described by this syndrome
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Schmidt's syndrome or polyglandular 2
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Syndrome occuring secondary to bilateral adrenalectomy often presenting with hyper pigmentation
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Nelsons syndrome
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Polyglandular syndrome type 1 is associated with mucocutaneous candidiasis, adrenal failure and this
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Hypoparathyroidism
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Malfunction of medial temporal love and amygdala resulting in hypersexuality and hyperorality
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Kluver-bucy syndrome
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Treatment of HIV is started for a CD4 count below this
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350
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Esophagitis in HIV with multnucleated giant cells on histology
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HSV
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Integrase inhibitor
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Raltegravir
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Steroids added to PCP treatment in these two situations
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A-a gradient >35 p02 < 70
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CCR5 inhibitor
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Maraviroc..selzentry
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Drug beginning with "I" that can cause crystalluria
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Indinavir
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Drug beginning with "I" that is used to treat hepatitis "C"
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Pegylated Interfeuron alpha 2a
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Treatment for pulmonary hypertension
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Iloprost
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Drug used to treat multiple sclerosis
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Interfeuron beta
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This drug is derived from the saliva of the gila monster
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Exenatide
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Blood pressure and LDL goal in diabetes mellitus
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Glutamic acid decarboxylase
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This DPP-IV inhibitor has been associated with URTI symptoms as a side effect
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Sitagliptin
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This 2009 trial demonstrated that intensive blood glucose control increased mortality in ICU patients
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Nice-sugar
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This form in influenza vaccine is live attenuated
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Intranasal
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Age range for HPV vaccine
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9-26
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Usual age at which pneumococcal vaccine is given in a healthy individual
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65 years
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Age at which herpes zoster vaccine is given in a healthy individual
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60 years
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Anyone born before this year is considered to be immune to mumps
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1957
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