Neuromuscular disease

Myasthenia gravis is a chronic autoimmune disease that targets the neuromuscular junction resulting in impaired impulse transmission and skeletal muscle weakness. The muscular weakness may exacerbate during periods of activity while improving after periods of rest, occurring with various severities. Muscles that control the eyes, eyelids, facial expression, swallowing, and talking can also be affected. Symptoms are presented as drooping of the eyelids, called ptosis, blurred or double vision, called diplopia, impaired speech, called dysarthria, shortness of breath, difficulty swallowing, waddling gait, and fatigued arms and legs. Although myasthenia gravis can affect people of all ages, it is most common among women under 40 and men above the…

Myasthenia gravis is a neuromuscular disorder or autoimmune disorder. An autoimmune disorder occurs when the immune system mistakenly attacks its own healthy tissue. Neuromuscular disorders involve the muscles and the nerves that control them. With myasthenia gravis, the body produces antibodies that block the muscle cells from receiving messages (neurotransmitters) from the nerve, which causes weakness of the voluntary muscles. Therefore, fewer receptors are available for stimulation, resulting…

Introduction Myasthenia gravis is a neuromuscular autoimmune disorder that affects the skeletal muscles in the body. This disorder is mainly characterized by periods of weakness in the body. The Latin meaning for myasthenia gravis is grave muscle weakness (Lewis 2007). In the United States the prevalence rate is 14 per 100,000 (Lewis 2007) myasthenia gravis can affect any age, but normally it affects people over the age of 50 (Lewis 2007) The mortality rate from myasthenia gravis…

between nerves and muscles is disturbed. The nerve endings will usually release a neurotransmitter substance called acetylcholine to the body’s muscles. Acetylcholine generates a muscle contraction. Those with myasthenia gravis have an absence of acetylcholine. In the case of myasthenia gravis, the body’s antibodies stop, change, or kill the acetylcholine receptors, inhibiting the muscle from contracting.The immune system creates these antibodies to fight off infection. Myasthenia gravis is…

Myasthenia Gravis is considered an “autoimmune neuromuscular disease” that is categorized by the different amounts of weakness of the skeletal muscles in the body. The cause of Myasthenia Gravis is a flaw in the transmission of the nerve impulses to the muscles in the body. When normal communication between nerves and muscles are distributed at the neuromuscular junction, Myasthenia Gravis occurs. In normal humans, when an impulse travels down a nerve, the nerve then releases a neurotransmitter…

“Myasthenia Gravis (MG) is a chronic autoimmune neuromuscular disease characterized by varying degrees of weakness of the skeletal (voluntary) muscles in the body.”(NINDS, 2014). Myasthenia Gravis derives from the Latin and Greek for ‘grave muscle weakness’. This weakness increases with long periods of activity and improves during periods of rest. The voluntary muscles of the body are controlled by nerve impulses sent from the brain. The impulses travel down the nerves where they meet the…

Keywords: neuromuscular, genetic, chloride channel, myotonia congenita, Thomsen’s, Becker’s, anaesthetic management, general anaesthesia, TIVA, non-depolarising muscle relaxant, laparoscopic surgery Abstract: Administering anaesthesia in a patient with nerve and muscle disorders is tricky due to multiple challenges- the unpredictable effects of neuromuscular blockade and dreaded risk of malignant hyperthermia. We present the management of a case of Myotonia Congenita, with an ovarian dermoid and…

Introduction Monoclonal gammopathy of undetermined significance (MGUS) is condition in which there is too much of a protein called monoclonal protein, or M protein, in the blood. MGUS can cause there to be too many cells in your blood and not enough space for healthy cells. This condition increases your risk of cancer. What are the causes? The cause of this condition is not known. What increases the risk? You are more likely to develop this condition if: You are African American. You are 50…

ABSTRACT: Myotonia congenita is a rare genetic neuromuscular disorder characterized by painless muscle stiffness, myotonia and generalized muscle hypertrophy with non-progressive course. We report a case series of children who were presented with myotonia, generalized hypertrophy and characteristic myotonic discharges on electromyography and showed good response to carbamazepine. This case series is aimed to make the readers aware of this rare entity which shows excellent response to treatment…

(2016, March 29). Bigger Chickens Bring a Tough New Problem: ‘Woody Breast’. Retrieved from The Wall Street Journal: http://www.wsj.com/articles/bigger-chickens-bring-a-tough-new-problem-woody-breast-1459207291 Jacob, D. J. (2015, May 15). Green Muscle Disease in Poultry. Retrieved from Extention: http://articles.extension.org/pages/66982/green-muscle-disease-in-poultry Rutz, F. (2015, May 18). Nutritional approaches to broiler breast meat quality. Retrieved from WATTAgNET Web Site:…