Methanol

Ethyl vinyl ether was used to protect –OH on glycidol based on a literature reported protocal.59 In a typical procedure, 0.675 mol glycidol and 200 mL ethyl vinyl ether were loaded in a round-bottom flask, to which 1.25 g TsOH was then added. The reaction was allowed to proceed at room temperature (RT) for 3h. The resulting mixture was then purified by washing with 100 ml saturated aqueous solution of NaHCO3 for 3 times. The organic layer obtained was dried by MgSO4. After filtration of MgSO4,…

calyx has the high content of phenolic compounds associating to antioxidant, and have the significant effect on β-carotene bleaching. In freeze-drying, extract in cold water could perform well in some antioxidant property than in hot water, 80 % methanol. We had H. sabdariffa calyx been extracted by cool water and had to freeze-dry, then detected the DPPH scavenging capacity, reducing power, ferrous ion chelating activity,…

INTRODUCTION: Losartan Potassium (LSP)[FIG.1.A], 2-n-butyl-4-chloro-1-[p-(o-1Htetrazol- 5-ylphenyl) benzyl]-imidazole-5 methanol monopotassium salt is a highly selective, orally active, non-peptide angiotensin II receptor antagonist indicated for the treatment of hypertension. It has a more potent active metabolite (II, 2-n-butyl-4-chloro-1-[2- (1H-tetrazol-5 yl) biphenyl- 4-yl) methyl] imidazole-5- carboxyl acid)[1]. The determination of Losartan has been carried out in tablets by HPLC,…

the past decade. This can be translated to over 510,000 tons just from last year alone. One of the primary causes of this is because trucks carrying the oil are going to factures 24 hours a day 7 days a week. Not only does oil affect the soil but methanol pollution created can have negative side effects on farm animals and aquatic life. Research has found that animals that drink water that is mixed with fracking wastewater were later found dead an hour later. Pregnant cows that had drank…

6. SUMMARY AND CONCLUSION 6.1 SUMMARY The current study deals mainly with phytochemical and pharmacological investigation of traditionally used medicinal plant Enicostemma littorale Blume. A perusal of the literature revealed that only fragmental information was available on this plant species regarding cytoprotective potential and immunohistochemistry. In addition the exact molecular mechanism of action of this plant species active compound swertiamarin is unknown and remote. Hence this study…

Chapter 1: Introduction 1.1 Nature of the Dissertation Identification, quantification and analysis Amoxicillin and Flucloxacillin Sugar free antibiotics which are manufactured at Athlone Laboratories by high liquid fluid chromatography (HPLC). The project also involves Method Transfer validation by analysis Amoxicillin Sugar Free for the new project of GSK Mayenne France, this involved Identification, quantification and analysis of carrying Amoxicillin Trihydrate API and Sodium Benzoate in…

In this experiment Sodium dodecyl sulfate (SDS) polyacrylamide gel electrophoresis (PAGE) was performed under reducing conditions to estimate the molecular weight of proteins within a sample. The protein sample was from the previous using anionic exchange chromatography to partially purify N-acetyl--D-hexosaminidase, Lab 3. The molecular weight was determined through the interpolation of a standard curve of proteins with a known molecular weight. The molecular weight of band 1 was determined to…

aureus based on the zone of inhibition which has a diameter range of 7mm to 10mm. In this study, the extract of hexane of S.aromaticum showed positive antibacterial properties against E. coli, and S. aureus for concentrations of 25, 50, 75, 100. The methanol extract showed positive against S. aureus for 75 and 100 mg/ml. The DCM extract showed positive for E. coli, S. aureus, (100 mg/ml). The comparison of the three extracts of clove oil shows that the hexane extract of clove oil has the highest…

compares the heat capacities of water and two other solvents. Compare the specific heat capacity of water to other substances (e.g ethanol) providing an example of why water is used in industry based on this property. Results & calculations 힓H = mC힓T Methanol CH3OH Propenol C3H8O Ethanol C2H5OH m = 3.6g m= 3.4g m=8.3g…

P value (6) and is soluble in methanol (50 mg/ml). It also shows pH dependent solubility. (Vamsi,2013) The wavelength selected for analysis was 265nm to reduce baseline noise at absorption maximum (257nm) of Tamoxifen citrate. Mobile phase composition or solvent strength plays an important role in RP-HPLC. An HPLC column packed with stationary phase of octadecyl carbon chain (C18)-bonded silica was used. A polar mobile phase such as mixture of organic solvent methanol and buffer was used. The…