The difference between the two being that IBD causes inflammation of the bowels and can lead to tiredness and rectal bleeding; whereas IBS does not cause inflammation, fatigue, or rectal bleeding. Ulcerative Colitis only affects the lining of the large intestine; unlike similar diseases such as Crohn’s disease, or irritable bowel syndrome that affects more than just the lining of the bowel. This is an immune disease that causes the inflammation to fight off an infection caused by the ulcers or…
role with multiple inflammatory diseases such as Inflammatory bowel disease, Arthritis, Gastritis, Asthma, Atherosclerosis. Various researches clearly point towards the hyper functioning of NFkB in aged mice there by promoting excess of undesired inflammation on the tissue and organ systems. The role of NFkB inhibitors definitely influence aging as seen in experiments on mice skin, resulting in cell and tissue regeneration. The Genetic modulation, or drug based inhibition of NFkB has shown delay…
or injury changes the body. Rheumatoid arthritis may cause swelling and intense pain throughout various joints, but it can also cause many other problems in the body. If the arthritis gets bad enough, it can cause a low count in red blood cells, inflammation around the heart and lungs, and a person could even develop a fever followed by low amounts of energy. Over weeks and months the autoimmune disease can worsen. Rheumatoid arthritis is one of the most common autoimmune diseases. With that…
HENOCH-SCHONLINE PURPURA Usually called HSP, is a condition that affects the small blood vessels, this inflammation is known as vasculitis, their become swollen and irritated. HSP can affect anyone, it’s most common in children aged 2-11, and boys are affected twice as often as girls. A seasonal variation with a peak incidence in spring has been noted. The disorder was named after two German physicians, Eduard Henoch and Johann Schonlein, who first described the disease in the 1800s. Sometimes…
and Treatment Sepsis is known as the medical complication that is due to the acute immune response of the body against the infection. The biochemicals that are spread in the blood stream to remove the infection causes swelling in the body. This inflammation becomes the root cause for organ damage and even the blood clotting during sepsis results in obstructed blood flow to limbs and internal organs that block the flow of nutrients and oxygen. In severe conditions, sepsis results in single or…
Sepsis was originally referred to as the presence of both suspected infection and two of the four criteria of the systemic inflammatory response syndrome (SIRS) in 1992. (Sepsis) As terminology emerged and progressed, new terms were introduced like, “severe sepsis” and “sepsis shock”. (Tupchong) When sepsis becomes more serious, it refers when the body has an organ dysfunction thus the term “severe sepsis” being created. From 1993 to 2003, severe sepsis had doubled in patients with the disease.…
repeat containing protein. A major part of the innate immune system is the inflammasome, which Cryopyrin is directly involved in the correct assembly of this molecule [6]. An inflammasome is the molecule that directs the process of inflammation in the body. Inflammation is the body’s way of signaling to leukocytes and other signal molecules to rush to the site of injury or disease to begin fighting it to prevent it from damaging tissue. The leukocytes fight whatever pathogens are present and…
Pneumonia is caused by an inflammatory response to an organism such as streptococcus pneumoniae or escherichia coli. This inflammation occurs in the alveolar sacs and the alveoli are filled with fluid, neutrophils, and there is also an increase in mucus production.The inflammation of the alveolar sacs leads to a decrease in gas exchange which leads to hypoxia (Lewis, 2014). There are several types of pneumonia and they include: community-acquired, medical care-associated, aspiration, and…
Plantar fasciitis is also characterized by the breakdown of collagen, scarring, and micro tears. It is a disorder of the ligament of bone at the insertion site. Many people feel that plantar fasciitis should be renamed as plantar fasciosis as inflammation in this condition plays a very small role. The symptoms and signs are considered and based on that diagnosis are done with ultrasound. The symptoms are similar in other conditions as well including ankylosing spondylitis, osteoarthritis,…
a substrate in contact with the skin. A chemical contact to the skin triggers damage to the epidermis and emission of interleukin 1, 6, 8, and the tumor necrosis factor (Simon, Aeberhard, Erdemoglu, & Simon, 2014). These releases bring about an inflammation process that clinically exhibits as reddened, cracked, and irritated dermis (Huether & McCance, 2012). Spongiotic dermatitis is a category four reaction triggered by environmental antigens named hapten that also triggers an immune response…