rug interactions are the harmful or beneficial effects of co administered medicinal products, these interaction may be synergistic or antogon istic pharmco kinetics or pharmaco dynamics, drug interactions exists between drugs anddrugs, drug and foods, drugs and herbs, benefits effects include convenience . Reduced toxicity and reduction. ANTIHISTIMINE, ANTIHISTIMINE, ASTHMA, ANALAGESIC, TYPHOID, HYPERTENSION, TUBERCULOSIS ANTIBIOTICS, FILARIA, RHEUMATOID ARTHRITIS, ANTIPYRITIC, ANTICANCER…
insomnia, and agitation. 5. here can be some withdrawal effects, especially with SSRIs with short half-lives. 6. May cause serotonin syndrome, especially if used with MAOIs. (ii) TCAs 1. Last line therapy for GAD. Can be used for refractory cases. 2. Imipramine is the first choice for GAD (iii) Benzodiazepines 1. Last line therapy for GAD. Can be used for refractory cases. 2. Alprazolam, Diazepam, Clonazepam, and Lorazepam are examples. It’s important to note that these are controlled…
drowsiness, fatigue, constipation, and dry mouth. TCAs (Tricyclic antidepressants) are drugs that are prescribed when SSRIs or any other medication doesn't work. The drugs TCA include amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine. The side effects are constipation, dry mouth, and fatigue. There are many other medications for depression but those are the most common…
Before Fluoxetine, or Prozac, there was a drug called imipramine or Tofranil. Because of the extreme possible side effects of this drug, scientists fully immersed themselves into discovering a better, less life altering antidepressant. Prozac was approved by the FDA on December 29th of 1987. In it’s first week…
Pharmacokinetics is the branch of pharmacology that describes how the body affects a specific drug after administration. A number of phases occur once the drug enters into contact with the gastro intestinal wall, these are described using the acronym ADME, starting with the mechanisms of absorption, which is the process by which a substance enters the blood circulation. Distribution, where the dispersion or dissemination of substances throughout the fluids and tissues of the body. ADME also…
Since the creation of antidepressants in the 1950s, this pharmaceutical drug has been under intense scrutiny from both scientists and civilians. This is because there is a vast range of views revolving around the use of antidepressants since various studies have questioned the effectiveness of the drug and the criteria set up for prescribing it. However, antidepressants deserve that apprehension because it affects society by incapacitating its members through their harmful side effects including…
Therapy is a great way of treatment for people struggling with depression. Medication is another form of treatment for the depressed, it is easy for the patient to become addicted. Once the depressed are done taking their medication they may not want to quit. Their antidepressants made them feel better so once the medicine is gone they may begin to feel empty again or as if they are missing something, Depression is more than just a sad mood. Almost 20% of Americans who suffer from depression…
AMPHETAMINE WITHDRAWAL Overview The repeated use of amphetamines will cause psychological AND physical dependence that may also result in withdrawal when the medicine aren't any longer being used. According to the United States National Library of medicine, once use of amphetamines suddenly stops, withdrawal symptoms quickly set in inflicting the brain and also the body to travel through a series of uncomfortable, not, therefore pleasure some reactions both psychologically and physically.…
Studies show that SSRIs treats depression and targets the three main PTSD clusters such as avoidance, re-experiencing, and hyperarousal. SSRIs are tolerable and have few side effects. Serotonin-norepinephrine reuptake inhibitors block the reuptake of the neurotransmitters. SNRIs such as duloxetine, venlafaxine, and desvenlafaxine act by preventing the reuptake of the neurotransmitters serotonin and norepinephrine (Greenberg, 2012). High concentrations of extracellular serotonin and…
methylphenidate, dexamphetamine, and permoline are also utilized in the management of ADHD. Various antidepressants are also essential in management of behavioral disorders in the syndrome. They include the tricyclic antidepressants (TCA) such as desipramine, imipramine, and clomipramine. Selective serotonin reuptake inhibitors used in the management of compulsiveness include fluoxetine, paroxetine, citalopram, and sertaline. They are less sedative compared to TCAs. Some less commonly used…