Gastroparesis

1.0 Background Gastroparesis is a condition of impaired motility function of the stomach to deliver food to distal alimentary tract without obstruction. The clinical associate with gastroparesis is a nonspecific and wide range of symptom from asymptomatic with delay gastric emptying time to severe nausea, vomiting loss of appetite, malnutrition needs a frequent administration in hospital 1,2 and poor quality of life. The pathophysiologic cause of developing this disease still not clearly understand aside from associated with vagus nerve is damaged. Most common diagnosis causes of this disease are idiopathic and the other two common diabetic and prior surgery involved with the vagus nerve. In general, gastroparesis doesn 't cure the condition.…

Gastroparesis (GP), or delayed gastric emptying, is a complex disorder characterized by nausea, vomiting, early satiety, and abdominal discomfort. Complications of GP not only lead to increased morbidity, increased time spent in the hospital, and significant nutritional deficits, but also impact the overall quality of life of those affected (Parrish, & McCray, 2014). Gastroparesis can occur in many settings with various symptoms as well as symptom severity. The clinical symptoms of GP include:…

When severe weight loss and restricted eating occurs, the body loses fat, leading to a weakening of the stomach muscles and damage to the extrinsic and intrinsic nerves. The extrinsic nerves connect the digestive organs to the spinal cord and brain, while the intrinsic nerves control the digestion and passing of food. Brown and Mehler (2015) have found that with weakened stomach muscles and damaged nerves, gastrointestinal complications arise and once the body weight is less than 15-20 percent…

Oxidative stress plays an important role in the development of diabetes complications. Our results demonstrate that increased production of ROS is the central and major mediator of both diabetes and diabetic gastroparesis. It is intriguing, although the production of ROS is a common mechanism, however, the activation of JNK and p38 MAPK in pylorus is unique and specific to gastroparesis. While we did not observe any ROS-mediated activation of JNK and p38 MAPK pathways in pylorus, there are…

Gastroparesis is a digestive system disorder; gastroparesis affects the stomach muscles. This disorder causes weakening of the stomach muscles, this causes poor churning and mixing of food by the stomach contractions and the normal movement of the stomach muscles that propel the food forward through the digestive tract is slowed down or in some cases they completely stop working. This prevents the food form being emptied from the stomach. Diet changes can be used to treat this condition.…

n the last few months my levels of pain and exhaustion have hit a whole new high. This has left me pretty much bedbound most days. Then awake and restless at night. Alongside all that, my Gastroparesis has flared, meaning I’m nauseous almost all the time. My stomach feels full and bloated and eating, or even drinking, causes severe pain. When everything piles up like this it’s hard to cope. I found myself breaking down and sobbing on an all too regular basis. I’m already taking slow release…

means weakness. Gastroparesis commonly referred as gastric emptying is a digestive disorder in which the food movement from the stomach to small intestine slows down or gets abnormal. In order to move food from the stomach to small intestine the stomach contracts. The stomach muscles are regulated by the vagus nerves. In order to break down food and movement food over gastrointestinal tract, the stomach muscle controlled by vagus nerve contracts. The digestion of food is mainly controlled by the…

Questions for Medical Nutrition Therapy: A Case Study Approach 5th ed. Case 8 – Gastroparesis 1. Identify the major physiological controls for gastric emptying. • Contraction and motility are major controls for gastric emptying involving autocrine, paracrine, and neuronal systems. • The interstitial cells of Cajal control the smooth muscle activity and the autonomic nervous system relays the message from input for the smooth muscle. o Neuropeptides, hormones and neurotransmitters affect…

Gastroparesis is a disease presenting in delayed emptying of the stomach’s contents. This can be caused on the grounds of an array of issues. Although this pathology/disease/disorder affects 25-50% of subjects diagnosed with diabetes, it can also affect people that have had surgery, infection, or hypothyroidism (Gregg). This postponing of gastric emptying means that it takes longer than usual for contents to pass through the stomach. According to Stephen Goldfinger, M.D., “Normally, your…

Eating?" by Sarah McCarry with Adee Braun seem to agree that competitive eating causes many health issues and risks while also providing a waste of food that could go to better places. Competitive eating is a hazard to lives and isn't needed in our society. Competitive eating competitions should be banned because they have many health risks and have become a hazard to competitors' health. According to Sarah McCarry's article, competitive eating has been know to have health risks for obesity,…