Discussion The research methods in the studies reviewed improved in sophistication and clarity over time from 2011 to 2016. Three of the studies determined that antibiotics resulted in a risk for increased BMI in boys but not in girls (Ajslev et al., 2011; Azad et al., 2014; Murphy, et al., 2014). In general, repeated exposures to antibiotics (Saari et al., 2015; Schwartz et al., 2016; Scott et al., 2016) or broad-spectrum antibiotics (Bailey et al., 2014), in particular macrolides (Saari et al., 2015), were found to be associated with an increase in BMI. Strengths and Limitations Most of the research reviewed controlled for potential confounders on the effect of antibiotics on BMI: mode of delivery, maternal pre-pregnancy weight, maternal smoking, maternal diabetes, birth weight, socioeconomic status, and steroid use. However, the indirect assessment of prescription and BMI data in the earlier studies, i.e. parent report, introduces a possibility of recall bias. Direct measurements and electronic access of prescription records increases data validity. In this regard, the more recently published studies have greater validity than earlier studies as the methodologies have been refined. Broad-spectrum antibiotics and macrolides were implicated more often than narrow-spectrum antibiotics in BMI increase, but the lack of consistent category definitions across the studies limits application of this finding. Recording specific antibiotic classes from health records, as in…
The data gathered from this experiment showed that chloramphenicol resulted in the largest zones of inhibition when S. epidermidis and S. enteritidis were exposed to it (Tables 1 & 2, Figure 2). Vancomycin caused the second-largest zones of inhibition in S. epidermidis, larger than the zones caused by nalidixic acid, but had no visible effect in S. enteritidis (Figure 2). When S. enteritidis was exposed to nalidixic acid, it created zones of inhibition just slightly smaller than the zones…
Introduction The drugs used in this experiment are Chloramphenicol and rifampicin. Both of these drugs are antibiotics however their methods of action are quite different. These drugs have different effects on the bacteria they are being used against. Rifampicin is a bactericidal drug and chloramphenicol is bacteriostatic. Bactericidal drugs interfere with the bacteria to such an extent that the bacteria die. They not only prevent new cells from growing but also cause a crucial aspect of the…
the P22 phage, a lysate was prepared for the transduction of chloramphenicol resistance from a resistant S. typhimurium LT2 strain to a sensitive strain of S. typhimurium. It is believed that P22 phages package 44 kb of chromosomal DNA at random with a 2% frequency and a 2% chance of homologous recombination events occurring (MIC302 lab manual). S. typhimurium has a chromosome length of approximately 4,857 kb, so it was calculated that 0.00036% is the percent chance that the gene for…
The fenicol groups of antibiotics are one of the generally utilized medications which are wanted to treat sicknesses relating to respiratory and digestive systems. These days, these gatherings of antibiotics are utilized as a part of veterinary prescription adequately. Fenicol gathering of anti-microbials incorporates a few regularly utilized medications like chloramphenicol and florfenicol. As of late, utilization of florfenicol has been expanded on account of its wellbeing in nature when…
evidence based approach to treating the topic Chloramphenicol is the commonest anti-toxin used to treat conjunctivitis. It is the minimum costly visual antibacterial and is accessible from drug stores without a solution for the treatment of intense bacterial conjunctivitis in grown-ups, more seasoned individuals furthermore, youngsters matured two years and over (Chaplin & Tey, 2017). g) In your opinion, which approach (between most expensive and least expensive) would you recommend and why –…
ribosomes. They do not affect human cells but only affect bacterial cells ribosomes by blocking them. Antibiotics classified under ‘Quinolones’ affect DNA reproduction, they cause the DNA strands to break then prevent the bacteria to repair the broken DNA strands. There are many more classifications. (Genetics and antibiotics, n.d.)The three antibiotics fall under different antibiotic classifications, Tetracycline is referred to as a glycylcycline, Chloramphenicol is classified under Amphenicols…
β-lactam antibiotics including ampicillin, ceftiofur and ceftriaxone (Aarestrup et al., 2004). In Salmonella, resistance to tetracycline is encoded by the tet genes. Most of the tet genes code for efflux pumps and several others code for ribosomal protection proteins. The majority of tet genes in bacteria are present on the mobile genetic elements such as plasmids, transposons, conjugative trasnposons and integrons (Chopra & Roberts, 2001). Antimicrobial resistance in Salmonella to…
B. cereus and slightly inhibit the growth of C. albicans. Chili powder and salt did not inhibit the growth of any bacteria. b. The purpose of the production of antibiotics by fungi and bacteria is to kill or inhibit the growth of other organisms. By inhibiting other bacteria from growing and surviving, the bacteria that produce the antibiotics are able to use up more of the limited sources that are found in their environments. They are then able to survive and reproduce better than if there was…
by diarrhea and the other, called emetic toxin, by nausea and vomiting. E. coli is the name of a type of bacteria that lives in your intestines and in the intestines of animals. Although most types of E. coli are harmless, some types can make you sick. Fifth step, we had gotten introduce to 6 types of antibiotics penicillin, gentamycin, ampicillin, chloramphenicol, streptomycin, and tetracycline. The most famous of all antibiotics, named for the fungal mold Penicillium notatum from which it is…