Aldosterone

1.What is it? Addison’s disease is a rare hormonal disorder and is a significant deficiency of the hormones that is created in the adrenal cortex. Hormones are chemical messengers that keep the body in balance by regulating functions like reproductions or our emotions. These hormones are produced in the adrenal glands, which is located at the top of each kidney. The adrenal glands has an outer part known as the cortex and an inner part known as the medulla. Adrenal glands produce epinephrine, also known as adrenaline, that is created during the time of stress that in response will raise blood flow and pulse rate. The outside of the adrenal glands, known as the cortex creates two critical hormones, aldosterone, and cortisol. The deficiency…

Why is Sharon is experiencing the following signs/symptoms? Please provide the specific pathophysiology. (4 points) •Jaundice: Jaundice occurs when your liver doesn’t metabolize bilirubin the way it’s supposed to. Accumulation of bilirubin or its conjugates in body tissues produces jaundice, which is characterized by high plasma bilirubin levels and deposition of yellow bilirubin pigments in the skin and other tissues. Jaundice caused during the hepatic phase can arise from abnormalities in the…

common endocrine disorder is known as adrenal insufficiency. This is where the adrenal gland releases too little of cortisol or aldosterone. Addison’s disease is a type of adrenal insufficiency. Symptoms likely include fatigue, upset stomach, dehydration, and skin changes. Cushing’s Disease is another endocrine issue. It is caused by an overactive adrenal gland. Some symptoms include obesity and increased thirst. It is common in children who take corticosteroids. Hyperthyroidism is another…

An anatomical change that Addison's disease can have on the nervous system is hyperpigmentation. With the insufficient levels of glucocorticoids, found in the blood, causes the pituitary gland to release more adrenocorticotropic hormone, or ACTH. In some cases, parts of this hormone are converted into melanocytes, which initiates production of melanin. This leads to darkening of skin cells in areas, such as 'Palmar creases, flexural areas, sites of friction, recent scars, vermilion border of the…

Congenital adrenal hyperplasia is the overdevelopment of the adrenal glands from birth. In a healthy person, cortisol is used to decrease the release of adrenocorticotropic hormone. ACTH is used by the pituitary gland which stimulates the adrenal gland. However, people with CAH have a genetic limitation where they are unable to produce correct amounts of cortisol. Without cortisol to exert a negative feedback on ACTH, it continues to be secreted causing the adrenal gland to secrete larger…

The body uses 3 different hormones to regulate the loss of fluid; antidiuretic hormone, aldosterone and atrial natriuretic peptide. Antidiuretic hormone and aldosterone slow down fluid loss from urine. The antidiuretic hormone will do this by allowing water in the urine to be taken back into the body in a specific area of the kidney. This allows more water to return to the bloodstream which in tur means urine concentration will rise and water loss will be reduced. Aldosterone’s main role in the…

The Causes and Effects of Stress The study of stress has gathered momentum with many different definitions with one describing the concept of stress as the emotional and physiological responses to circumstances that are too difficult to cope with or to some and which one has no choice but to endure them. Over the last few years, the term stress and it’s causes and effects have always had our attention. For some long period of time stress has always been around. Have you ever wondered what causes…

One of the other types of stress is Episodic Acute Stress. When acute stress starts to happen, more often it is called episodic acute stress. People who always seem to have a continuous crisis in their life seem to have episodic acute stress. People that tend suffer from this always seem to be in a rush, they take too much on and tend not to be able to organize themselves to deal with demands and pressures. People who have Episodic Acute stress are often short-tempered, irritable, and anxious.…

Angiotensin Converting Enzyme (ACE) inhibitors lower blood pressure and produce vasodilation by inhibiting ACE – blocking the conversion of angiotensin I to angiotensin II, key mediators of the Renin-Angiotensin-Aldosterone System (RAAS). RAAS is the main mechanism for controlling BP. Angiotensin II is a vasoconstrictor and works by binding to angiotensin I receptors on smooth muscle – these are joined to a Gq protein and the IP3 signal transduction pathway. ACE usually breaks down bradykinin.…

restriction in the blood vessels, this hormone can increase the blood pressure which ultimately overworks the heart and body (Sahay, & Sahay, 2012). Aldosterone is a hormone produced by the adrenal cortex, this hormone helps in regulating the blood pressure. Whenever there is a decrease in blood flow to the kidneys, this system is activated. The typical flow of these hormones is renin release angiotensin, which then releases…