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9 Cards in this Set

  • Front
  • Back
INNATE IMMUNITY

- list the cells/pathways involved
(CNN MD)

- Complement pathway
- Neutrophils
- Natural Killer cells

- Macrophages
- Dendritic cells
ADAPTIVE IMMUNITY

- list the cells/pathways involved
- T cells
- B cells
- Antibodies
HUMORAL IMMUNITY

- major players?
- regulated by what cell?
- B-cells
- Anti-bodies

- Th2 Helper cells
HUMORAL IMMUNITY

- provides immunity (primarily) against what pathogens?
- Extracellular microbes
(esp. encapsulated microbes)

- Toxins

(some viruses also)
HUMORAL IMMUNITY

- requires what signal #1

- requires what signal #2
Signal #1:
(B-cell) CD40 & CD40L (Th cell)

Signal #2:
IL-4, IL-5, IL-6 (from Th cell)
HUMORAL IMMUNITY

- upon activation, B-cells can change into what?
- Plasma cells (to secrete Ab)

- Memory cells
(which undergoes Affinity maturation)
CELL MEDIATED IMMUNITY

- major players?
- regulated by what cell?
- T-cells
- Macrophages
- NK cells

- Th1 Helper cells
CELL MEDIATED IMMUNITY

- provides immunity (primarily) against what pathogens?
- INTRACELLULAR microbes

- Cancer cells
CELL MEDIATED IMMUNITY

- unlike humoral immunity's B-cells, which secrete IgM receptor, CMI requires what?
- Direct Cell to Cell contact