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9 Cards in this Set
- Front
- Back
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INNATE IMMUNITY
- list the cells/pathways involved |
(CNN MD)
- Complement pathway - Neutrophils - Natural Killer cells - Macrophages - Dendritic cells |
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ADAPTIVE IMMUNITY
- list the cells/pathways involved |
- T cells
- B cells - Antibodies |
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HUMORAL IMMUNITY
- major players? - regulated by what cell? |
- B-cells
- Anti-bodies - Th2 Helper cells |
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HUMORAL IMMUNITY
- provides immunity (primarily) against what pathogens? |
- Extracellular microbes
(esp. encapsulated microbes) - Toxins (some viruses also) |
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HUMORAL IMMUNITY
- requires what signal #1 - requires what signal #2 |
Signal #1:
(B-cell) CD40 & CD40L (Th cell) Signal #2: IL-4, IL-5, IL-6 (from Th cell) |
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HUMORAL IMMUNITY
- upon activation, B-cells can change into what? |
- Plasma cells (to secrete Ab)
- Memory cells (which undergoes Affinity maturation) |
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CELL MEDIATED IMMUNITY
- major players? - regulated by what cell? |
- T-cells
- Macrophages - NK cells - Th1 Helper cells |
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CELL MEDIATED IMMUNITY
- provides immunity (primarily) against what pathogens? |
- INTRACELLULAR microbes
- Cancer cells |
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CELL MEDIATED IMMUNITY
- unlike humoral immunity's B-cells, which secrete IgM receptor, CMI requires what? |
- Direct Cell to Cell contact
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