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21 Cards in this Set
- Front
- Back
Diseases caused by Circoviridae
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Chicken Anemia Virus (CAV)
Porcine Circovirus (PCV) Psittacine Beak and Feather Disease Virus (PBFDV) |
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Diseases caused by Parvoviridae
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Canine Parvovirus 2 (CPV)
Feline Panleukopenia Virus (FPV) Porcine Parvovirus (SMEDI) |
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Name the disease caused by Porcine Circovirus
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Postweaning Multisystemic Wasting Syndrome (PMWS)
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Describe the basic pathogenesis of PCV infection:
1. Transmission 2. How it causes dz |
1. Transmission: Fecal-oral (major), verticle & respiratory (minor)
2. Virus is non-cytopathic: causes chronic inf'n->cytokine storm->wasting |
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Important factors for PCV dz
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Immune stimulant triggers (endemic infection with not all pigs sick). Intenstive management key player, genetics and vaccination
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Describe the major lesions of PCV Dz
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Key: granulomatous lymphadentitis with lymphoid depletion. Every system affected: Resp, Hepatic, GIT, Renal, Cardiac, Reproductive (gilts).
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List major clinical signs of PCV Dz
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Wasting, respiratory, diarrhea, icterus, pallor
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How is PCV Dz diffinately diagnosed?
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IHC or In Situ Hybridization
NOT serology or PCR because ubiquitous in the environmnent of pig barns |
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How can PCV Dz be controlled?
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Good Biosecurity: cleaning, decrease mixing, good air quality, vaccination (sows and/or pigs)
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Describe what PBFD (Psittacine Beak and Feather Dz) would look like.
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Loss and abnormal growth of feathers, abnormal beak growth
Immunosuppression Secondary Infections (decrease immunity) |
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How is PBFD Diagnosed?
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Skin/Feather Biopseys (ok)
PCR (on blood sample),(good for enviro too!) If +, sample again 60-90 days later |
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Describe Chicken Anemia Virus dz:
Transmission Clinical Signs Diagnosis |
Horizontal and verticle trans.
Acute immunosuppression: *anorexia *depression *anemia *wasting Dx: serology, virus demonstration in tissue |
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T or F: Parvoviruses as naked, therefore hard to decontaminated eniro.
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True
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From what virus did the Canine Parvovirus evolve?
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Feline Panleukopenia Virus and the Mink Parvo virus
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Describe the pathogenesis of Parvovirus infections
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Fecal-Oral-lymph nodes(primary replication)-viremia-spread to heart, GIT, brain, fetuses.
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What type of cells do Parvoviruses replicate in? What enzyme is required?
List important replication sites. |
Actively dividing cells (S-phase).
Need cellular DNA Polymerase *Crypt cells of intestine *Peyer's Patches *Cardiac Myocytes *Cerebellum (granular cells) |
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Describe the sequelae of in utero infections with Parvovirus for dogs and cats.
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Kittens: cerebellar hypoplasia (hypermetric gate)
Puppies: myocarditis leads to fibrosis and heartfailure. |
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Discuss the clinical signs of postnatal infections with parvovirus.
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Depression
Bloody diarrhea,vomiting (dehydration and shock) fever leukopenia, neutropenia Secondary Bacterial infection |
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How is parvovirus diagnosed?
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Capture ELISA (less sensitive, but ok for practice)
EM Virus Isolation Hemagglutination |
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How can parvovirus be controlled?
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Disinfection
Vaccination: must overcome maternal AB (biweekly or 'hot' vaccines) |
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Describe what effect Procine Parvo has on the herd
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Reproductive Problems!
SMEDI Stillbirth Mummification Embryonic Death Infertility |