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117 Cards in this Set
- Front
- Back
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abdominal pain, ascites, hepatomegaly
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Budd-Chiari syndrome (posthepatic venous thrombosis)
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achilles tendon xantoma
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familial hypercholesterolemia (decreased LDL receptor signaling)
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adrenal hemorrhage, hypotension, DIC
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waterhouse-friderichsen syndrome (meningococcemia)
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arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints
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Marfan's syndrome (fibrillin defect)
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athlete with polycythemia
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erythropoitin injection
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back pain, fever, night sweats, weight loss
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pott's disesase (vertebral tuberculosis)
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bilateral hilar adenopathy, uveitis
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sarcoidosis (non caseating granulomas)
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blue sclera
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osteogenesis imperfecta (collagen defect)
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bluish line on gingiva
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burton's line (lead poisoning)
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bone pain, bone enlargement, arthritis
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paget's disease of the bone (increase osteoblastic and osteoclastic activity)
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bounding pulses, diastolic heart murmur, head bobbing
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aortic regugritation
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buttterfly facial rash and raynaud's phenomenon in young female
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systemic lupus erythematosus
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cafe au lait spots, lisch nodules (iris hamartoma)
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neurofibromatosis type 1+ pheochromocytoma, optic gliomas
neurofibromatosis type 2 + bilateral acoustic neuromas |
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cafe au lait spots, polyostotic fibros dysplasia, precocious puberty
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McCune-Albright syndrome (mosaic G protein signaling mutation
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calf pseudohypertrophy
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muscular dystrophy (most commonly Duchennes) x linked recessive deletion of dystrophin gene
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cherry red spot on macula
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tay sach's (ganglioside accumulation) or neimann pick (sphingomyelin accumulation) central retinal artery occlusion
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chest pain on exertion
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angina (stable, moderate exertion; unstable, minimal exertion)
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chest pain, pericardial effusion/friction rub, persistent fever following MI
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dressler's syndrome (autoimmune mediated post- MI fibrinous pericarditis, 1-12 weeks after acute episode)
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child uses arms to stand up from squat
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gower's sign (duchenne muscular dystrophy
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child with fever develops red rash on face that spreads to body
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slapped cheeks (erythema infectiosum/fifth disease: parovirus B19)
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chorea, dementia, caudate degeneration
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huntington disease (autosomal dominant CAG repeat expansion)
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Chronic exercise intolerance with myalgia, fatigue, painful cramps, myoglobinuria
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McArdle's disease (muscle glycogen phosphorylase deficiency)
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Cold intolerance
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hypothyroidism
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conjugate lateral gaze palsy, horizontal diplopia
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internuclear ophthalomoplegia (damage to MLF; bilateral (MS) unilateral (stroke)
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continuous machinery heart murmur
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PDA (close with indomethacin, open with misoprostol)
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cutaneous/dermal edema due to connective tissue deposition
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myxedema (caused by hypothyroidism, graves' disease (periorbital)
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dark purple skin/mouth nodules
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kaposi's sarcoma (usually AIDS patient (gay men) associated with HHV-8
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deep, labored breathing/ hyperventilation
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kussmaul breathing (diabetic ketoacidosis)
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dermatitis, dementia, diarrhea
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pellagra (niacin B3 deficiency)
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dilated cardiomyopathy, edema, polyneuropathy
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wet beriberi (thiamine b1 deficiency)
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dog or cat bite resulting in infection
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pasteurella multocida (cellulitis at inoculation site)
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dry eyes, dry mouth, arthritis
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Sjogrn's syndrome (autoimmune destruction of exocrine glands)
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dysphagia (esophogeal webs) glossitis, iron deficiency anemia
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plummer-vinson syndrome (may progress to esophageal squamous cell carcinoma)
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elastic skin, hypermobility of joints
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ehler-danlos syndrome (type 3 collagen defect)
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enlarged hard left supraclavicular node
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virchow's node (abdominal metastasis)
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erythroderma, lymphadenopathy, hepatosplenomegaly, atypical T cells
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sezary syndrome (cutaneous T cell lymphoma or mycosis fungoides)
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facial muscle spasm upon tapping
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chvostek sign (hypocalcemia)
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fat, female, fourty, fertile
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acute cholelithiasis (bile duct blockage)
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fever, chills, headache, myalgia following antibiotic treatment for syphilis
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jarisch- herxheimer reaction (rapid lysis of spirochetes results in toxin release)
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fever, cough, conjunctivitis, coryza, diffuse rash
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measles (morbillivirus)
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fever, night sweats, weight loss
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b sympotoms (lymphoma)
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fibrous placques in soft tissues of the pelvis
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peyronie's disease (connective tissue disorder)
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gout, mental retardation, self mutilating behavior in a boy
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Lesch-nyhan syndrome (HGPRT deficiency, X linked recessive)
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green- yellow rings around peripheral cornea
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Kayser-Fleischer rings (copper accumulation from wilson's disease)
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hamartomatous GI polyps, hyperpigmentation of mouth/feet/hands
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Peuts-Jeghers syndrome (genetic benign polyposis can cause bowel obstruction and increase cancer risk
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hepatosplenomegaly, osteoporosis, neurologic symptoms
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gaucher's disease (glucocerebrosidase deficiency)
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hereditary nephritis, sensorineural hearing loss, cataracts
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alport syndrome (mutation in alpha chain of collagen 4
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hypercoagulability (leading to migrating DVTs and vasculitis)
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trousseau's syndrome (adenocarcinoma of pancreas of lung)
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hyperphagia, hypersexuality, hyperorality, hyperdocility
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Kluver-bucy syndrome (bilateral amygdala lesion)
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hyperreflexia, hypertonia, positive babinski sign
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UMN damage
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hypertension, hypokalemia, metabolic alkalosis
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conn's syndrome
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hyporeflexia, hypotonia, atrophy
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LMN damage
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hypoxemia, polycythemia, hypercapnia
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blue bloater "chronic bronchitis, hyperplasia of mucous cells
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indurated, ulcerated genital lesion
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nonpainful: chancre ( primary syphilis treponema pallidum)
painful with exudate: chancroid (hemophilus ducreyi) |
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infant with failure to thrive, hepatosplenomegaly, neurodegeneration
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neimann-pick disease (genetic sphingomyelinase deficiency)
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infant with hypoglycemia, failure to thrive, and hepatomegaly
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Cori's disease (debranching enzyme deficency)
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infant with microcephaly, rocker bottom feet, clenched hands, structural heart defect
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edwards syndrome (trisomy 18
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keratin pearls on a skin biopsy
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squamous cell carcinoma
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large rash with bulls eye appearance
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erythema choniculum migrans from Ixodes tick bite (lyme disease Borrelia)
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lucid interval after traumatic brain injury
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epidural hematoma (middle meningeal artery rupture)
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male child, recurrent infections, no mature b cells
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bruton's disease (x linked agammaglobulinemia)
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mucosal bleeding and prolonged bleeding time
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glanzmann's thrombasthenia (defect in platelet aggregation due to lack of GpIIbIIIa
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multiple colon polyps, osteomas/soft tissue tumors, impacted/supernumerary teeth
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gardner's syndrome (subtype of FAP)
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myopathy (infantile hypertrophic cardiomyopathy), exercise intolerance
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pompe's diseae (lysosomal alpha 1,4 glucosidase deficiency)
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necrotizing vasculitis (lungs) and necrotizing glomerulonephritis
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wegener's (c-ANCA positive) and goodpasture's syndrome (anti basement membrane antibodies)
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neonate with arm paralysis following difficult birth
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erb-duchenne palsy (superior trunk (c5-c6) brachial plexus injury "waiter's tip)
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no lactation postpartum, absent menstruation, cold intolerance
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sheehan's syndrome (pituitary infarction
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nystagmus, intention tremor, scanning speech, bilateral internuclear ophthalmoplegia
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multiple sclerosis
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oscillating slow/fast breathing
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cheyne-stokes respiration (central apnea in CHF or increase intracranial pressure)
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painful blue fingers/ toes, hemolytic anemia
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cold agglutination disease (autoimmune hemolytic anemia caused by mycoplasma pneumoniae infectious mononucleosis)
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painful, pale, cold fingers/toes
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raynaud's syndrome (vasospasm in extremities)
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painful, raised red lesions on palms and soles
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osler's nodes (infective endocarditis)
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painless, erythmatous lesions on palms and soles
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janeway lesions (infective endocarditis)
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painless jaundice
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cancer of pancreatic head obstructing bile duct
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palpable purpura on buttox/legs, joint pain, abdominal pain
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henoch-schonlein purpura (child) (IgA vasculitis affecting skin and kidneys)
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pancreatic, pituitary, parathyroid tumors
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MEN1 (autosomal dominant)
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pink complexion, dyspnea, hyperventilation
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Pink puffer (emphysema; centroacinar (smoking) or panacinar (alpha antitrypsin deficiency)
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polyuria, acidosis, growth failure, electrolyte imbalance
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fanconi syndrome (proximal tubular reabsorption defect)
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positive anterior drawer sign
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anteriar cruciate ligament injury
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ptosis, miosis, anhidrosis
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horner's syndrome (sympathetic chain lesion)
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pupil accomodates but doesnt react
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Argyll Robertson pupil (neurosyphilis)
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Rapidly progressive leg weakness that ascends (following GI/URTI)
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Gullian Barre syndrome (autoimmune acute inflammatory demyelinating polyneuropathy)
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rash on palms and soles
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coxsackie A, 2ndary syphilis, rocky mountain spotted fever
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recurrent colds, unusual eczema, high serum IgE
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Hyper IgE syndrome (job's syndrome: neutrophil chemotaxis abnormality)
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Red "currant jelly" sputum in alcoholic or diabetic patients
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klebsiella pneumonia
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Red, itchy, swoollen rash of the nipple areaola
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paget's disease of the breast (underlying neoplasm)
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red urine in the morning, fragile RBCs
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paroxysmal nocturnal hemoglobinuria
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renal cell carcinoma (bilateral) hemangioblastomas, angiomastosis, pheochromocytoma
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von Hippel-Lindau disease (dominant tumor suppresor gene mutation)
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resting tremor, rigidity, akinesia, postural instability
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parkinson's disease (nigrostriatal dopamine depletion)
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retinal hemorrhages with pale centers
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roth's sports (bacterial endocarditis)
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severe jaundice in neonates
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crigler-najjar syndrome (congenital unconjugated hyperbilirubinemia)
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severe RLQ pain with rebound tenderness
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mcburney sign (apppendicitis)
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short stature, increased incidence of tumors/leukemia, aplastic anemia
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fanconi's anemia (genetic loss of DNA crosslink repair, often progresses to AML)
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Single Palm crease
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simian crease of downs syndrome
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situs inversus, chronic sinusitis, bronchiectasis, infertility
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kartagener's syndrome (dynein arm defect affecting the cilia)
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skin hyperpigmentation
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addison's disease (primary adrenocortical insufficiency causes increase ACTH and alpha MSH production)
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slow, progressive muscle weakness in boys
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becker's muscular dystrophy (x linked missense mutation in dystrophin; less severe then duchenne's)
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small irregular red spots on buccal lingual mucosa with blue-white centers
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koplik spots (measles; rubeola virus)
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smooth flat moist white lesions on genitals
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condylomata lata secondary syphilis
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splinter hemorrhages on fingernails
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bacterial endocarditis
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strawberry tongue
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scarlet fever, kawasaki disease, toxic shock syndrome
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streak ovaries, congential heart disease, horseshoe kidney, cystic hygroma at birth
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turner syndrome (45xo, short stature, webbed neck, lymphedema)
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sudden swolen painful big toe joint, tophi
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gout podagra (hyperuricemia)
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swollen gums, mucous bleeding, poor wound healing, spots on skin
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scurvy (vitamin C deficiency cant hydroxylate proline/lisine for collagen synthesis
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swollen, hard, painful finger joints
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osteoarthritis (osteophytes on PIP (bouchard's nodes) DIP (heberden's nodes)
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systolic ejection murmur (crescendo-decrescendo)
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aortic valve stenosis
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thyroid and parathyroid tumors, pheochromocytoma
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MEN 2A autosomal dominant ret mutation
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thyroid tumor pheochromocytoma ganglioneuromatosis
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MEN 2B autosomal dominant ret mutation
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toe extension/fanning upon plantar scrape
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babinski sign (UMN lesion)
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unilateral facial drooping involving forehead
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bells palsy LMN CN VII palsy
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urethritis, conjunctivitis, arthritis in a male
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reactive arthritis associated with HLA B27
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vascular birthmark (port wine stain)
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hemangioma (benign but associated with sturge weber syndrome
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vomiting blood following esophagogastric laceration
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mallory weiss syndrome (alcoholic and bulimic patient)
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waxy casts with very low urine flow
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chronic end stage renal disease
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WBC casts in urine
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acute pyelonephritis
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Weight loss, diarrhea, arthritis, adenopathy
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whipples disease (tropheryma whippelii)
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worst headache of my life
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subarachnoid hemorrhage
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