Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
32 Cards in this Set
- Front
- Back
Howdo you diagnose C. diff colitis? |
· C difficile toxin! (pcr reaction or enzymeimmunoassay) |
|
Describepathogenesis of C diff: |
· intestinal overgrowth of C diff leads toproduction of toxins: enterotoxin A causes watery diarrhea and cytotoxin Bcauses colonic epithelial cell necrosis and fibrin deposition |
|
Describethe clinical manifestations of babesiosis: |
· asymptomatic to hemolytic anemia associated withjaundice, hemoglobinuria, renal failure, and death! |
|
Isrash a feature of babesiosis |
· NO! |
|
Describeclinical features of ehrlichiosis |
· fever, malaise, headache, nausea, vomiting,(labs show leukopenia and thrombocytopenia but hemolysis and jaundice are notcommon) |
|
Howdo you treat cmv esophagitis |
· Ganciclovir |
|
Whatdo you see on biopsy of cmv esophagitis |
· Intranuclear and intracytoplasmicinclusions (hsv esophagitis showsintranuclear inclusions) |
|
Txof herpes simplex esophagitis vs. cmv esophagitis: |
· acyclovir vs. gancyclovir |
|
Whatis a common cause of endocarditis associated with nosocomial utis? |
· Enterococci, especially enterococcus faecalis(not staph epidermidis; that is with catheters) |
|
Islack of current current ART a contraindication to receiving MMR in an adultwith cd4> 200? |
NO |
|
Howcan you distinguish hiv versus mono? |
· Diarrhea and rash are less common in mono buttonsillar exudate is more common in mono |
|
The13-valent pcv13 is recommended for all adults age __ and the 23 one isrecommended ___ months later: |
65;6-12 |
|
PPDinduration tx for healthy individuals |
· 15 mm and over |
|
PPDinduration tx for recent immigrants (< 5 years), drug users, residents andemployees of high-risk settings, mycobacteriology lab, diabetes,corticosteroid, leukemia, esrd, malabsorption, or children< 4: |
· 10 and over mm |
|
PPDinduration tx for hiv positive, recent tb contacts, previously healed tb onx-ray, or organ transplant and immunosuppressed people? |
· 5 and over! |
|
Txfor active pulmonary tuberculosis: |
· 4 drugs for 2 months; then r and I for 4 months(total of 6 months) |
|
Txof latent tb: |
· 9 months of INH or INH for 6 and rifampin for 4months; |
|
Whatis typical tx for hep C? |
· peginterferon and ribavirin with additionalprotease inhibitor for genotype 1 (i.e. telaprevir or boceprevir) |
|
Whoare candidates for chronic hep C therapy? |
· Age > 18, detectable serum hep C virusRNA< compensated liver disease (INR < 1.5, no ascites), other stable labslike cbc, liver biopsy showing chronic hepatitis fibrois, |
|
Whatdo you suspect for patient with tick bite, leukopenia, thrombocytopenia,elevated aminotransferases and what do you use to treat? |
· Ehrlichiosis; doxycycline |
|
Erythromycinis good treatment for what two unique things? |
· Legionnaires and mycoplasma |
|
Whatare the four phases of chronic hep B? |
· immune tolerance, immune clearance, inactivecarrier state, hbE-Ag-negative chronic hepatitis |
|
Howdo you followup patient with hep B in immune clearance phase? |
· Serial alt and hbeAg (need 3 normal alt and 2 or3 normal hbv dna levels over 12 month period to be inactive carrier!) |
|
Whatis the preferred hiv screening test: |
· HIV p23 antigen and antibodies; if positive thendo western blot; then you can do plasma hiv rna testing if really not convincednegative |
|
Howdo you treat entamoeba histolytica |
· ? Metronidazole |
|
Didanosinecan cause what? |
· Pancreatitis |
|
Abacavircan cause what |
· ? Hypersensitivity |
|
Nrtican cause what? |
· Lactic acidosis |
|
Nnrtican cause what? |
· Stevens-johnson syndrome |
|
Nevirapinecan cause what? |
· Liver failure |
|
Indinavircan cause what |
· Crystal-induced nephropathy |
|
Whatis Ludwig angina and what is source of infection |
· Infection of submandibular and sublingual gland;infected tooth is source of infection |