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25 Cards in this Set
- Front
- Back
- 3rd side (hint)
Cardiac and Smooth muscle, gland cells, and nerve terminals from MEDULLA
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Parasympathetic.
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First Order Neurons: Ach
Second Order Neurons: Ach, M |
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Sweat Glands
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Sympathetic.
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First Order Neurons: ACh
Second Order Neurons: ACh, M |
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Cardiac and Smooth Muscle, gland cells, nerve terminals
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Sympathetic.
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First Order Neurons: ACh
Second Order Neurons: NE alpha beta. |
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Renal Vascular Smooth Muscle
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Sympathetic
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First Order Neurons: ACh
Second Order Neurons: D, D1 |
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Adrenal Medula
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Release of NE and Epi
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ACh
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Skeletal Muscle
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Somatic, Voluntary
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ACh, N (first order neuron only)
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Botulinum toxin
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prevents release of NT at all cholinergic terminals
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Muscarinic ACh receptors
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G protein coupled receptors that act thru second messengers. M1, M2, M3, M4, M5
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Nicotinic ACh receptors
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Ligand-gated Na/K channels. NN is found in autonomic ganglia and NM are found in neuromuscular junctions.
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Receptor: alpha 1
Sympathetic G protein class Major Functions |
Receptor: alpha 1
Sympathetic G protein class: q Major Functions |
Receptor: alpha 1
Sympathetic G protein class: q Major Functions: Increase vascular smooth muscle contraction, increased pupillary dilator muscle contraction (mydriasis), increased intestinal and bladder sphincter muscle contraction. |
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Receptor: alpha 2
Sympathetic G protein class? Major Functions? |
Receptor: alpha 2
Sympathetic G protein class: i Major Functions |
Receptor: alpha 2
sympathetic G protein class: i Major Functions: decrease sympathetic outflow, decreased insulin release. |
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Receptor: Beta 1
Sympathetic G protein class? Major Functions? |
Receptor: Beta 1
Sympathetic G protein class: s Major Functions |
Receptor: Beta 1
Sympathetic G protein class: s Major Functions: Increase HR, contractility, renin release, and lipolysis. |
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Receptor: Beta 2
Sympathetic G protein class? Major Functions? |
Receptor: Beta 2
Sympathetic G protein class: s Major Functions |
Receptor: Beta 2
Sympathetic G protein class: s Major Functions: Vasodilation, Bronchodilation, Increased HR, contractility, lipolysis, insulin release. Decreased uterine tone. |
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Receptor: M1
Parasympathetic G protein class? Major Functions? |
Receptor: M1
Parasympathetic G protein class: q Major Functions |
Receptor: M1
Parasympathetic G protein class: q Major Functions: CNS and enteric nervous system |
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Receptor: M2
Parasympathetic G protein class? Major Functions? |
Receptor: M2
Parasympathetic G protein class: i Major Functions? |
Receptor: M2
Parasympathetic G protein class: i Major Functions: Decrease the HR and contractility of atria |
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Receptor: M3
G protein class? Major Functions? |
Receptor: M3
Parasympathetic G protein class: q Major Functions? |
Receptor: M3
Parasympathetic G protein class: q Major Functions: Increase exocrine gland secretions, increase gut peristalsis, bladder contraction, bronchoconstriction, pupillary sphincter muscle contraction (miosis), ciliary muscle contraction (accomodation). |
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Receptor: D1
G protein class? Major Functions? |
Receptor: D1
Dopamine G protein class: s Major Functions? |
Receptor:D1
Dopamine G protein class: s Major Functions: Relaxes renal vascular smooth muscle |
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Receptor: D2
G protein class? Major Functions? |
Receptor:D2
Dopamine G protein class: i Major Functions? |
Receptor: D2
Dopamine G protein class: i Major Functions: modulates transmitter release, especially in brain |
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Receptor: H1
G protein class? Major Functions? |
Receptor: H1
Histamine G protein class: q Major Functions? |
Receptor: H1
Histamine G protein class: q Major Functions: increase nasal and bronchial mucus production, contraction of bronchioles, pruritis, and pain. |
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Receptor: H2
G Protein Class? Major Functions? |
Receptor:H2
Histamine G Protein Class: s Major Functions? |
Receptor: H2
Histamine G Protein Class: s Major Functions: increase gastric acid secretion |
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Receptor: V1
G Protein Class? Major Functions? |
Receptor: V1
Vasopressin G Protein Class: q Major Functions? |
Receptor: V1
Vasopressin G Protein Class: q Major Functions: Increase vascular smooth muscle contraction. |
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Receptor: V2
G Protein Class? Major Functions? |
Receptor: V2
Vasopressin G Protein Class: s Major Functions? |
Receptor: V2
Vasopressin G Protein Class: s Major Functions: Increase water permeability and reabsorption in the collecting tubules of the kidney ("V2 is found in the 2 kidneys") |
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Kiss and Kick until your sick of Sex
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Qiss and Qiq until youre Siq of Sqs.
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HAVe 1 M&M
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H1, alpha 1, V1, M1, M3
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Gq--> phospholipase C --> PIP2 --> DAG (Protein kinase C) and IP3 (increase intracellular calcium)
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MAD 2's
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M2, Alpha2, D2 (Gi)
B1, B2, D1, H2, V2 (Gs) |
Adenyl Cyclase (BLOCKED by Gi, ACTIVATED by Gs) ---> ATP to cAMP ---> Protein Kinase A ----> Increased intracellular calcium in heart, decrease myosin light chain kinase in smooth muscle.
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