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15 Cards in this Set
- Front
- Back
ANA + peripheral pattern
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SLE
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ANA + diffuse pattern
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nonspecific
SLE, drug-induced lupus, RA (low titer, normal elderly |
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ANA + speckled pattern
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nonspecific
high titers in MCTD, low in normal elderly |
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ANA + centromere pattern
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limited scleroderma (CREST), PBC
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ANA + nucleolar pattern
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scleroderma, Sjogren syndrome
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anti-ds-DNA
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SLE ONLY (60-75%)
is an indicator of dz activity DO NOT find in drug-induced SLE |
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anti-Sm(ith)
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SLE ONLY (25%)
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anti-SS-A (Ro)
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- SLE, neonatal SLE, Sjogren syndrome, ANA negative SLE.
- NOT seen in scleroderma - assoc w/DR3 - neonatal lupus w/congenital heart block, Ab passive transfer from mom |
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anti-SS-B (La)
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SLE, Sjogren syndrome (30%)
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anti-U1-RNP
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MCTD (100%), SLE
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anti-histone
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drug-induced lupus (95%) and SLE (25%)
- main use is to rule out drug-induced lupus |
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anti-topoisomerase 1
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Diffuse scleroderma
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anti-mitochondrial Ab
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PBC
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anti-Jo
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polymyositis with mechanic's hands, arthralgias, ILD
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anti M12
anti PM1 |
sclerodema-myositis overlap syndromes
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