Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
48 Cards in this Set
- Front
- Back
route of administration of biologics
|
injection or infusion
|
|
What is the brand name for a biologic used for the treatment of rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis?
|
Enbrel
|
|
What is the brand name for etanercept
|
Enbrel
|
|
What is the brand name for a medication that is a synthetic version of a protein developed from the saliva of the Gila monster??
|
Byetta
|
|
What is the brand name for trastuzumab?
|
Herceptin
|
|
What is the brand name for a biologic used for the treatment of breast cancer?
|
Herceptin
|
|
What biologic medication is used for the treatment of diabetes?
|
Byetta
|
|
What is the brand name for quadrivalent HPV Types 6, 11, 16, and 18 recombinant vaccine?
|
Gardasil
|
|
What is the brand name for a biologic vaccine for prevention of cervical cancer, vulvar cancer, vaginal cancer, genital warts, and various precancerous genital lesions caused by certain types of human papillomavirus
|
Gardasil
|
|
What is the brand name for infliximab?
|
Remicade
|
|
What biologic medication is used for the treatment of Crohn disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis?
|
Remicade
|
|
What 2 terms refer to products that are claimed to have the same mechanism of action and treat the same clinical indications as the original biologic?
|
"biosimilar" or "follow-on biologic"
|
|
Name 3 follow-on biologics that are marketed in third-world countries and are in development in the US?
|
erythropoietin, growth hormone, & insulin
|
|
What are three classes of commonly used medications that are increasing in popularity and market share?
|
Biologics (biotics), nutraceuticals, combination drugs
|
|
The FDA defines _______________________________ as “therapeutic and diagnostic products that combine drugs, devices, and/or biological products.”
|
combination drugs
|
|
a combination of ezetimibe (brand name Zetia) and the statin drug simvastatin (brand name Zocor), used in the treatment of dyslipidemia
|
Vytorin
|
|
a combination of rosiglitazone (Avandia) and glimepiride (Amaryl), used in the treatment of type 2 diabetes
|
Avandaryl
|
|
combination of repaglinide (brand name Prandin) and metformin HCl (Fortamet), used in the treatment of type 2 diabetes
|
Prandimet
|
|
combination of atorvastatin (Lipitor) to treat hypercholesterolemia and amlodipine (Norvasc) to treat hypertension
|
Caduet
|
|
combination of amlodipine (Norvasc) and valsartan (Diovan), used in the treatment of hypertension
|
Exforge
|
|
Which class of medications does not have to be approved by the FDA before marketing?
|
nutriceuticals
|
|
One notable example of a nutraceutical is the use of ______________ in pregnant women to help prevent neural tube defects in the baby
|
folic acid
|
|
Name the nutraceutical:
There is evidence that these fatty acids lower triglycerides, reducing the risk of death, heart attack, dangerous heart rhythms, and strokes in people with known cardiovascular disease & slow the buildup of plaques. |
Omega-3
|
|
Name the nutraceutical:
microorganisms that may help with digestion and offer protection from harmful bacteria |
Probiotics
|
|
Name the nutraceutical:
an antioxidant that may help maintain a healthy cardiovascular system |
Coenzyme Q10
|
|
Name the nutraceutical:
may enhance the immune system, contribute to cardiovascular health, and reduce cancer risk |
Antioxidants
vitamin E, vitamin C, beta-carotene, coenzyme Q10 |
|
In terms of the FDA, what does NME stand for?
|
new molecular entity
|
|
What is a new molecular entity used to treat schizophrenia?
|
Latuda
|
|
What medication class does Botox belong to?
|
biologics
|
|
Which of the following is responsible for the rise in popularity of combination drugs?
a. Government requirements and restrictions b. Consumer convenience and safety c. Manufacturer convenience and safety d. Electronic health records |
b. Consumer convenience and safety
|
|
The combination of atorvastatin and amlodipine marketed as which of the following drugs?
A. Jalyn B. Caduet C. Advil D. ASA |
B. Caduet
|
|
All of the following are considered biologic medications except which answer below?
A. Humulin B. Enbrel C. Herceptin D. Protonix |
D. Protonix
|
|
What is one of the primary routes of biologic administration?
A. Tablets B. Topical C. Injection D. Inhalation |
C. Injection
|
|
To what class of medication does Coenzyme Q10 belong?
A. Combination B. Biosimilar C. Nutraceutical D. New molecular entity |
C. Nutraceutical
|
|
What is the expected result when prescribing probiotics?
a. Lower blood pressure b. Aid with digestion c. Treat restless leg syndrome d. Treat obstructive sleep apnea |
b. Aid with digestion
|
|
Krystexxa is a new biologic approved by the FDA in 2010. What is the generic name for this drug?
a. Ibuprofen b. Gardasil c. Pegloticase d. Pantoprazole |
c. pegloticase
|
|
Actemra
|
tocilizumab
Rheumatoid arthritis biologic |
|
Ampyra
|
dalfampridine
multiple sclerosis NME |
|
Vpriv
|
velaglucerase alfa
Gaucher disease--a genetic disease in which a fatty substance (lipid) accumulates in cells and certain organs NME |
|
Xiaflex
|
Collagenase clostridium histolyticum
Dupuytren contracture biologic |
|
Asclera
|
polidocanol
Varicose veins NME |
|
Carbaglu
|
carglumic acid
Chronic hyperammonemia NME |
|
Natazia
|
estradiol valerate; estradiol valerate dienogest
Oral contraception NME |
|
Lumizyme
|
alglucosidase alfa
Pompe disease -- an inherited disorder caused by the buildup of a complex sugar called glycogen in the body's cells. The accumulation of glycogen in certain organs and tissues, especially muscles, impairs their ability to function normally. biologic |
|
Jevtana Kit
|
cabazitaxel
Metastatic prostate cancer NME |
|
Prolia
|
denosumab
Osteoporosis biologic |
|
Pradaxa
|
dabigatran etexilate mesylate
Prevent blood clots and strokes in atrial fibrillation NME |
|
Dulera
|
formoterol fumarate; mometasone furoate
Asthma |