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3 Cards in this Set

  • Front
  • Back

Hyperparathyroidism

Radiographic features


1. subperiosteal bone resorption


classically affects the radial aspects of the proximal and middle phalanges of the 2nd and 3rd fingers


medial aspect of tibia, femur, humerus


lamina dura: floating teeth (not specific)


2.subchondral resorption


lateral end of the clavicles


symphysis pubis


sacroiliac joints


3.subligamentous resorption


ischial tuberosity


trochanters


inferior surface of calcaneus and clavicle


4.intracortical resorption: cigar/oval-shaped or tunnel-shaped radiolucency in the cortex


5.terminal tuft erosion (acro-osteolysis)


6.rugger jersey spine


7.osteopenia


8.brown tumours


9.salt and pepper sign in the skull (pepper pot skull)


10.chondrocalcinosis

Secondary hyperparathyroidism

Findings in secondary (and tertiary) hyperparathyroidism are often associated with the osteosclerosis of renal osteodystrophy and the osteomalacia of vitamin D deficiency:



subperiosteal bone resorption


osteopenia


osteosclerosis, e.g. rugger jersey spine


soft tissue calcification


superscan: generalised increased uptake on Tc-99m pertechnetate bone scan (focal uptake with adenoma)


superior and inferior rib notching

Subtypes of Hyperparathyroidism

primary hyperparathyroidism


parathyroid adenoma (~80%)


multiple parathyroid adenomas (4%) 5


parathyroid hyperplasia (10-15%) 2,5


parathyroid carcinoma (1-5%) 4,5


parathyromatosis (very rare)


secondary hyperparathyroidism


caused by chronic hypocalcaemia with renal osteodystrophy being the most common cause (others include malnutrition, vitamin D deficiency) 4


results in parathyroid hyperplasia 7


tertiary hyperparathyroidism


autonomous parathyroid adenoma caused by the chronic overstimulation of hyperplastic glands in renal insufficiency