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18 Cards in this Set

  • Front
  • Back

digestion definition and 4 components

chemical alteration of food into absorbable chemicals


-PH changes, GI motility, biological detergents, enzymes

what part of the body is the detergent supplier, and which is the enzyme supplier (neutralizer)

detergent: liver


enzyme: pancreas

4 layers of GIT with sublayers

mucosa (epithelium, lamina propria, muscularis mucosa)


submucosa


muscularis externa


serosa

layers of epithelium (2 and where do they face), transport through it (2, name them),

basolateral (face blood) and apical (face lumen)




1- transcellular: need two proteins on basal and apical surfaces


2- paracellular: tight junction seal

lamina propria: what type of tissue, what is it in (3), and what type of cells

-connective tissue


-nerve fibres, small blood vessels, lymphatic vessels


-immune and inflammatory cells

muscularis mucosa involved in what and (and not involved in what)

villi movement, not in contraction of GIT

submucosa: plexus of...


relays info where


what is in it

-plexus of nerve cell bodies


-relays info to and from mucosa


-connective tissue, blood vessels, lymphatic vessels

muscularis externa: 3 layers

thick inner layer of muscle: narrowing


myenteric nerve plexus


thin outer layer: shortening

portal vein drains blood from where to where

from circulation to liver

purpose of portal circulation is to allow liver to what (2)

remove harmful substances


process nutrients

venous supply referred to as...


most circulation is how

in series


in parallel

reflexes of GI initiated by (4)

swollen volume


osmolarity


PH


[specific digestion contents]

reflexes of GI propogated by (3)

mechanoreceptors


osmoreceptors


chemoreceptors

myenteric plexus influences what vs influence of submucosal plexus

myenteric: smooth muscle


submucosal: secretion

4 types of chemical messengers and their targets

endocrine: distant targets (hormones)

paracrine: close


neurocrine: close


autocrine: acts on itself

4 most popular hormones

CCK, GIP, secretin, gastrin

CCK pathway (triggered by, what does it act on, feedback)

-triggered by amino acids and fatty acids


released into the blood


-acts on pancreas to release digestive enzyme


gall bladder for bile for acid breakdown


-fats and amino acids are absorbed and CCK stops (negative feedback)

more stimualtion=

more contraction