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13 Cards in this Set
- Front
- Back
Ferrous Sulfate/Gluconate/Fumarate
1)MOA 2)CU 3)AE |
1)Oral, provides iron
2)Iron Deficiency Anemia; Give for 3 months after correct cause of the anemia 3)Black Stools, nausea, cramps |
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Iron Dextran
1)MOA 2)CU 3)AE |
1)Parenteral, provides iron
2)Iron Deficiency Anemia; give if cant tolerate oral iron, or have extensive chronic anemia 3)Hypersensitvity reaction; Headache, fever, arthralgia |
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Na Ferric Gluconate Complex
1)MOA 2)CU 3)AE |
1)Parenteral, provides iron
2)Iron Deficiency Anemia; give if cant tolerate oral iron, or have extensive chronic anemia 3)Headache, Fever, Arthralgia |
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Iron Sucrose
1)MOA 2)CU 3)AE |
1)Parenteral, provides iron
2)Iron Deficiency Anemia; give if cant tolerate oral iron, or have extensive chronic anemia 3)Headache, Fever, Arthralgia |
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Deferoxamine
1)MOA 2)CU 3)What causes acute iron toxicity? 4)What causes chronic iron toxicity? 5)Most efficient way of treating iron toxicity? |
1)Iron Chelator: binds to absorbed iron and complex excreted in urine and feces
2)Acute and Chronic Iron Toxicity 3)Child Eats Iron Supplements 4)Hemosiderosis, Thal Major, Transfusions 5)Phlebotomy |
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Vitamin B12
1)MOA 2)CU |
1)Provides B12
2)Treats megaloblastic anemia (d/t B12 defic) (helps with both the anemia and neuro syndrome) (but takes 5 years for B12 stores in body to get used) |
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Folic Acid
1)CU |
1)Treats megaloblastic anemia (d/t Folic Acid defic)(helps with only Anemia)(have only 6 months of folic acid stores)
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Erythropoietin
1)MOA 2)CU 3)AE 4)What does it do for athletes? |
1)inc release of reticulocytes from BM
inc JAK/STAT receptors on RBC progenitors 2)Anemia of Chronic Renal Failure 3)HTN, Thrombotic episodes, Faster head and neck tumor growth 4)Inc RBC conc ->inc O2 delivery (banned by olympics) |
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Darbepoetin
1)MOA |
1)Long Acting EPO (has 3X half life of EPO, and decreased clearance)
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Filgrastrim
1)MOA 2)CU 3)AE |
1)Stimulates neutrophil production/function
2)Inc neutrophils after cancer chemotherapy 3)G-CSF ->bone pain GM-> Fever Capillary Damage, Arthralgias |
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Sargramostin
1)MOA 2)CU 3)AE |
1)Stimulates neutrophil production/function
2)Inc neutrophils after cancer chemotherapy 3)G-CSF ->bone pain GM-> Fever Capillary Damage, Arthralgias |
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IL-11
1)MOA 2)CU |
1)Inc megakaryocyte progenitors -> inc platelets
2)Thrombocytopenia after cancer chemo (thus dec need for platelet transfusions) |
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Hydroxyurea
1)MOA 2)CU 3)AE 4)How long does it take? |
1)Inc HbF (dilutes HbS)
2)Pain related to Sickle Cell Disease 3)Bone Marrow Suppression, Cutaneous Vasculitis 4)Several Months |