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44 Cards in this Set
- Front
- Back
Prednisone is what drug class? |
Glucocorticoid |
|
Mineralocorticoids maintain ______ and _________ balance |
Fluid and electrolyte |
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Name a mineralocorticoid |
Fludrocortisone (Florinef) |
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What is the main mineralocorticoid and what does this mean? |
Aldasterone. Na and fluid retention |
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Contraindications for a _______________ includes systemic fungal infections |
Corticosteroid |
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Adrenal can take up to __ weeks to suppress and _____ to recover |
2 weeks, 9-12 months |
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How do you determine lowest possible dose in steroids? |
Taper until symptoms worsen |
|
DOC for adrenocortical insufficiency |
Hydrocortisone/cortisone |
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DOC for nonendocrine disorders for anti-inflammatory, antiallergic, immunosuppressive effects |
Prednisone |
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DOC for cerebral edema. Can penetrate BBB well. |
Dexamethasone |
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Major adverse reaction for corticosteroids |
Suppression of HPA axis |
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You can abruptly stop corticosteroids as long as tx is under __ days |
7 |
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Corticosteroid dosage must be ___________ during times of stress |
Increased |
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Nasal corticosteroids can take ___ weeks to work |
2 |
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Must taper corticosteroids if taking for longer than __ weeks |
2 |
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Thyroid hormone can still stay in the blood for __ weeks after starting antithyroid drugs |
6 |
|
Levothyroxine take on empty stomach or with meals? |
EMPTY stomach! |
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Levothyroxine is what percent protein bound? |
99% |
|
Propylthiouracil (PTU) (Thiomide) tx HYPERthyroidism by |
Inhibiting production of thyroid hormone and conversion of T4 to T3 |
|
This drug is used for tx during thyroid storm, pre thyroidectomy, and before or after radioactive iodine therapy |
PTU |
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This med can be given while the pt is waiting for hyperthyroid med to start working |
Propranolol |
|
Levothyroxine May be given IV to tx |
Myxedema coma |
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Radioactive iodine can cause hypothyroidism, and may take up to __ months to tx hyperthyroidism |
3 |
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Radioactive iodine is usually a one time dose administered in an outpatient setting. If high dose is used, pt may need to be isolated for __ days (half life of the drug) |
8 |
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May take up to __ months for radioactive iodine to take effect |
6 |
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Do not administer thyroid hormones if HR is > _____ due to drug causing increased workload to the heart. USE CAUTIOUSLY IN PTS WITH CV DISEASE! |
100 bpm |
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PTU usually given every ___ hours |
Q8H |
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After age ___, bone resorption exceeds formation |
35 |
|
Recommended daily dose of cholecalciferol |
400-1000 IU |
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This drug class works by binding to bone and preventing calcium to leave to the blood |
Bisphosphonates |
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Where are bisphosphonates metabolized? |
They’re not lol. They be excreted directly in urine |
|
Take bisphosphonates with or without food? |
Without. They’re poorly absorbed in the GI tract. Take 30 min before meals |
|
Routes of calcitonin (3) |
SQ, Intranasal, IM |
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This med is a version of Parathyroid hormone |
Forteo |
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This osteoporosis drug can cause cancer |
Forteo |
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This drug acts by increasing osteoblasts |
Forteo |
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When do you give calcitonin and why |
Bedtime, reduces flushing and nausea |
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Other than sitting up for 30 min to prevent acid after giving bisphosphonates, what is something to look out for |
Jaw pain |
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Average adult pancreas secretes ___-___ units of insulin daily |
40-60 |
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Basal insulin amount is normally __-__ units per hour |
1-2 |
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Symptoms in type 1 diabetics occurs when only ___-___% of beta cells remain |
10-20% |
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What insulin is used for emergencies since it is the only insulin that can be given IV |
Regular (Humulin R, Novolin R) |
|
Isophane (NPH) is what type of insulin |
Intermediate (used long term!) “The cloudy clouds are long term lol” |
|
Black box warning for biguanide |
Lactic acidosis |