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16 Cards in this Set
- Front
- Back
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Neointima
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Intimal thickening of a vessel due to SMC proliferation
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Markers for Endothelial cells in a vessel
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CD31, CD34, vWF
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Why is Lp(a) a risk factor for Atherosclerosis?
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Lp(a) has structural homology to Plasminogen Activator; hence it binds to PA receptors and blocks PA from clearing clots.
Lp(a) has apoprotein B100 and apoprotein(a) |
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How does homocystiene cause Atherosclerosis?
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It bings to LDL causing them to aggregate.
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List reasons for chronic endothelial injury?
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Hyperlipedemia, Hypertension, DM, Smoking, Immune Response, Toxins, Virus, Hemodynamic Factors, Homocystiene
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What is Trousseau's sign?
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Migratory thromboplebitis. Associated with visceral malignancies, especially carcinoma of the pancreas.
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What is Homan sign?
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pain with calf squeeze or dorsiflexion of foot
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familial Milroy disease
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one of the Primary causes of lymphedema – lymphatic obstruction
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Rickettsia
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Vector-borne obligate intracellular bacteria that infects EC and SMC causing vasculitis.
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von Hippel-Landau disease
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Cavernous Hemangioma occuring in brain and other organs
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Glomus tumor
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Very painful lesion under fingernail. (mx shows vascular spaces lined by nests of uniform cells).
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Nevus Flammeus
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typical “birthmark”
-usually on head or neck -histology shows dilated vessels |
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Spider Telangiectasia
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-dilated subcutaneous arterioles in a radial array with pulsatile center
-blanches when pressure applied to center |
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Bacillary Angiomatosis is caused due to...
Associated with... |
infection with gram-negative bacilli of Bartonella genus
Commonly associated with immunodeficiency diseases (AIDS) |
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Hemangioendothelioma
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term for a broad spectrum of neoplasms intermediate in their properties between benign hemangiomas and malignant angiosarcomas
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Endothelial cell marker is...
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CD31
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