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5 Cards in this Set
- Front
- Back
What can happen when adherence to certain receptors on the phagocyte's surface
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Respiratory burst:
activation of NADPH oxidase production of superoxide radical superoxide converted to peroxide by superoxidase dismutase |
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Oxygen-dependent killing
Oxygen-independent killing |
For gram +
gram - |
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Evasion by:
1. Thick peptidoglycan 2. Cover with capsule 3. MAC (membrane attack complex) at arm's length 4. Sialic acid which induces avoidance 5. enzymes that degrade C3b |
Evasion of complement
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Inhibition of chemotaxis via
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1. cord factor: inhibits PMN migration
2. elastase: inactivates C5a 3. C5a peptidase: degrades C5a |
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Inhibition of phagocytosis via
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Capsule
Porins M protein which blocks binding of C3b Protein A |