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18 Cards in this Set
- Front
- Back
What is the definition of prognosis?
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Prediction of the expected outcome of a disease with or without treatment
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The greek definition of prognosis in greek is to come to know beforehand, how is this possible?
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Use population data to make a prognosis
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What are the 5 things that a prognosis should include (ideally)?
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1) The variability in course relative to treatment options
2) A time reference 3) Risk of treatment-related death (or other untoward reaction) 4) Cost 5) Nature of benefit attainable |
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What is the definition of case fatality rate?
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% of patients w/ a disease who die of it
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What is the definition of survival rate?
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% of patients surviving a defined period of time from some point in the course of their disease
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What is the definition of response rate?
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% of patients showing some evidence of improvement after an intervention
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What is the definition of remission rate?
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% of patients entering a phase in which disease is no longer detectable
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What is the definition of recurrence rate?
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% of patients who experience a return of disease after a disease-free interval
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What are the 2 questions that are the rationale for the life table?
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1) What is the likelihood of surviving for x years after diagnosis
2) What is the likelihood of surviving another year, given that the patient has already survived for y years since diagnosis |
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How do you calculte the cumulative probability of surviving different lengths of time?
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It's a mutliplicative property so just multiple the probability of survival for each individual year
e.g. Probability of surviving 3 years= P1 x P2 x P3 |
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What does a survival curve show
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Cumulative survival over time
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How do you compare multiple survival curves?
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Steeper slope= worse survival
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Why can the tail towards the right side of a survival curve be deceiving?
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Beause as the population decreases even with the same survival rate it will look like a not very steep slope
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What is the y-value of a survival curve?
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Cumulative survival up to that time point
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What does a survival curve show
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Cumulative survival over time
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How do you compare multiple survival curves?
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Steeper slope= worse survival
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Why can the tail towards the right side of a survival curve be deceiving?
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Beause as the population decreases even with the same survival rate it will look like a not very steep slope
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What is the y-value of a survival curve?
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Cumulative survival up to that time point
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