Icp Drugs, Ketamine

Front 1

Induction Drugs

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very lipid soluble, fast on, fast off, short duration (3-5m), Note propofol/etomidate burn on injection, ketamine has Analgesic effects, and thiopental has a high pH…watch out for crystallization of drug if added w/ acidic drug…instead, push thiopental, flush through into body w/ IV fluid, then do acidic drug

Induction Drugs
Group 2

Front 2

Ketamine
Drug
(trade name)

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(Ketalar)

Induction Drugs
Group 2

Front 3

Ketamine
Class

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Phencyclidine

Induction Drugs
Group 2

Front 4

Phencyclidine

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PCP is an arylcyclohexylamine derivative, and, in pharmacology, it is a member of the family of dissociative anesthetics.
|| PCP works primarily as an NMDA receptor antagonist, which blocks the activity of the NMDA receptor.[3] Other NMDA receptor antagonists include ketamine, tiletamine, and dextromethorphan.

Front 5

Ketamine
Uses

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Induction,
Analgesia, Amnesia

Induction Drugs
Group 2

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Ketamine
[ Supplied ]

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10, 50, 100 mg/ml

Induction Drugs
Group 2

Front 7

Ketamine
Dosing--card

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2mg/kg IV
(1-2); 5mg/kg (3-5) IM

Induction Drugs
Group 2

Front 8

Ketamine
Dosing--Stever

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Analgesia 0.2-0.5mg/kg; Induction 1-2mg/kg IV (4-8mg/kg IM)

Induction Drugs
Group 2

Front 9

Ketamine
Caution

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Emergence Delirium, Drug Interactions-- dec.
amnt inhaled agent needed, potentiates NMB

Induction Drugs
Group 2

Front 10

Ketamine
Notes

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lasts 1 hour, "Special K", deriv.
of PCP

Induction Drugs
Group 2