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42 Cards in this Set
- Front
- Back
Hgb value norm |
12-18 |
|
Hct value norm |
% = 37-54 |
|
TIBC norm |
250-450 |
|
MCV norm |
80-100 |
|
MCHC norm |
32-36% |
|
Low MCV indications. |
Iron deficiency anemia Thalassemia |
|
High MCV indications |
B12 or Folate deficiency ETOH Liver failure Drugs |
|
Normocytic anemia differentials |
Chronic disease sickle cell renal failure blood loss hemolysis |
|
Iron deficiency anemia blood size and color |
Microcytic hypochromic |
|
Most common cause of amemia? |
Iron deficiency |
|
S/s of IDA |
Pica Dyspnea and mild fatigue HA Palpitations Tachy Pallor |
|
What does ferritin show? |
Iron stores (norm 18-270) |
|
In IDA what will IIBC be? |
High = more binding room |
|
Tx of IDA |
Oral iron (not with antacids) Take with vitamin C to increase absorption
|
|
Size & color in Thalassemia? |
Micro hypo |
|
Which populations see more Thalassemia? |
Mediterranean, African, Indian, Middle Eastern, Asian |
|
What will TIBC be in Thalassemia? |
Normal (250-450) |
|
What will ferritin be in Thalassemia? |
Normal |
|
Normal Serum Iron level |
50-150 |
|
What happens in Thalassemia? |
Abnormal Hgb production |
|
Folic acid defeciency appearance? |
Macro Normo |
|
Cause of Folic Acid deficiency ? |
Poor intake ETOH |
|
Difference between folic acid and B 12 ? |
No neuro s/s in Folic Acid |
|
Pernicious Anemia appearance |
Macro Normo |
|
Cause of pernicious anemia? |
Malabsorption of B12 |
|
s/s of Pernicious Anemia |
Weakness Glossitis (red beefy) Palpatations Paresthesias Loss of fine motor control + Romberg and Babinski |
|
Tx for pernicious Anemia |
B12 IM daily x1 week Lifelong monthly tx |
|
Anemia of chronic disease appearance |
Normo normo |
|
Differentials for ACD |
Chronic inflammation Infection Renal failure Malignancy |
|
TIBC in ACD |
Low |
|
Serum Iron in ACD |
Low |
|
Serum Ferritin in ACD |
High |
|
Tx ACD |
Nutrition Tx underlying disease Epopoeitin |
|
Supplement Iron in ACD? |
No, ferritin is high |
|
Idiopathic Thrombocytopenia Purpura (ITP) description |
Autoammore destruction of platelets |
|
Idiopathic Thrombocytopenia Purpura (ITP) labs and signs |
Bleeding gums, easy bruising, kidney bleeding Bone marrow analysis low platelets with all other causes R/0 |
|
Idiopathic Thrombocytopenia Purpura (ITP) TX |
High dose corticosteroids IV gamma globulin platelet transfusion |
|
Heparin-induced Thrombocytopenia TX |
Give Argatroban or Lepiratin Need bone marrow aspiration to distinguish from ITP |
|
DIC patho |
Coagulation factors are used in clotting the thrombin also activates the fibrinolytic system and dissolves clots into fibrin degredation products (FDP) Results in clotting and diffuse bleeding High mortality |
|
DIC Labs |
Platetet <150 Fibrinogen < 170 Low RBC *Increased FDP > 45 PT >19 PTT >42 D-Dimer elevated |
|
DIC transfusion products and rationale |
Platelet = thrombocytopenia FFP= replace clotting factors Cryoppt = replace fibrinogen |
|
Sideroblastic anemia |
Microcytic normal TIBC |