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15 Cards in this Set
- Front
- Back
Vibrio species:
(1) oxidase (2) motility (3) serogrouping |
(1) oxidase-pos
(2) single polar flagellum (3) O and H antigens |
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Vibrio cholerae
Epidemiology: (1) human disease serotypes (2) historic epidemics of what? (3) risk factors (4) infection source |
(1) O1, O139
(2) diarrhea (3) H. pylori, O blood type (4) contaminated water, food |
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Vibrio cholerae
Pathogenesis: (1) pathogen or toxin-caused? (2) effects of toxin |
(1) toxin
(2) decreased Na+ absorption, increased Cl- secretion |
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Vibrio cholerae
Symptoms: (1) pos sx (2) neg sx (3) gen appearance (4) serious complication (5) unique in children (6) pregnant woman prognosis |
(1) watery diarrhea, vomit
(2) strain, tenesmus, abd pain (3) sunken eyes, dry mucous (4) acute renal failure (5) seizures, fever (6) fetal loss in 50% cases |
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Vibrio cholerae
Treatment: (1) FIRST thing to do (2) type of drugs (3) vaccine |
(1) rehydration (Ringer's lactate)
(2) antimicrobials (3) ideal vaccine not available |
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Vibrio parahaemolyticus:
(1) sources (2) pos sx (3) deaths in which pop? (4) treatment |
(1) shellfish
(2) watery diarrhea, desentery, gastro (3) elderly, kids, immunocomp'd (4) tetracyclines, quinolones |
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Vibrio vulnificus:
(1) mortality rate (2) natural habitat? (3) population affected? (4) pos sx (5) treatment |
(1) 25%
(2) marine environ (3) immunocomp'd (4) fever, chills, low BP, skin lesions (5) tetracyclines, quinolone |
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Campylobacter
General Characteristics: (1) best growth conditions (2) sources (3) isolation techniques |
(1) microaerophilic, C. jejuni = 42 C
(2) undercooked meat (3) filtration |
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Campylobacter:
virulence factors (5) |
(1) flagella
(2) high-MW plasmid (3) PEB1 antigen (4) C. jejuni = O antigen (5) C. fetus = serum-resistant capsule |
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Campylobacter
Treatment: (1) diagnosis (2) sx for presumptive therapy (3) resistance |
(1) stool, blood culture
(2) fever, bloody diarrhea, >8 BMs/day (3) increasing to macrolides, quinolones |
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Campylobacter jejuni:
(1) common sx (2) commonly affected age group? (3) clinical manifestations (6) |
(1) diarrhea
(2) under 2 years (3) acute enteritis, acute colitis, pseudoappendicitis, bacteremia, Guillain-Barre, reactive arthritis |
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Campylobacter fetus:
clinical manifestations (4) |
(1) diarrhea
(2) bacteremia (3) vasc infections (4) CNS infections |
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Helicobacter pylori
Characteristics: (1) enzyme production (2) motility (3) virulence factors + role |
(1) urease: urea -> NH3
(2) corkscrew motion (3) CagA = gastric cancer VacA = immunosuppressive |
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Helicobacter pylori:
clinical manifestations (7) |
(1) chronic active gastritis
(2) pangastritis = gastric cancer/ulcers, less acid (3) antral gastritis = duodenal ulcers, more acid (4) peptic ulcer disease (cag+) (5) gastric ulcers (6) gastric cancer (7) MALT tumor |
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Helicobacter pylori
Treatment: (1) diagnosis (2) don't treat which pts? (3) drugs |
(1) endoscopy, urea breath test
(2) children, non-ulcer, asymptomatic (3) acid suppressant + antibiotic |