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45 Cards in this Set

  • Front
  • Back

Drug classes

Anti acids


H2 receptor antagonists


proton pump inhibitors


anti ineffective for H. Pylori bacteria


cytoprotective

aluminum hydroxide antacids

amphojel, AlternaGEL, Alu-Cap



DO NOT TAKE WITHIN 1-2 HOURS OF MANY OTHER MEDS

aluminum hydroxide antacids

uses


raises ph gastric secretion, neutralize acid


phosphate binding removing high levels of phosphate from the body (renal)



most frequent side effect constipation

combination antacids

aluminum hydroxide= constipation


magnesium hydroxide= diarrhea



is a combination to balance out side effects



usual dose is 30ml



DS is after it means its double strength the 15ml is usually ordered

H2 Blockers

nizatidine, cimetidine, famotidine, ranitidine



inhibit histamine action on h2 receptor in gastric parietal cells which decrease gastric acid secretions

H2 Blockers

prevents heartburn, tx gastric & duodenal ulcers, tx heartburn & GERD



common side effect mental confusion especially cimetidine in the elderly

proton pump inhibitors

lansoprazole, pantroprazole, omeprazole, esomeprazole



decrease gastric acid formation by stopping hydrogen transport into parietal cells



take 2-4 weeks to become effective



short term 6-8 weeks gastric & duodenal ulcers, gastritis and GERD



long term use increase risk for stomach cancer



take ac - before meals



DO NOT CRUSH CHEW OR OPEN

anti ineffectives

adjuvant therapy for treatment of peptic ulcer disease when the helobacter pylori bacteria is present



TCN age 8 or pregnant women



PCN & semi synthetic PCN



Veetids, PenVeek, augmenting, amoxicillin



emycin


zithromycin - diarrhea



PERMANTLY STAINS TEETH BROWN

cytoprotective agents

sucralfate


misoprotsol



prevent and treatment of


peptic and duodenal ulcers


gastroesophageal reflux (GERD)


prophylactically with NSAID drug use

sucralfate

binds with gastric acid to form a thick paste which adheres to ulcers and protects them from stomach acids



can also be used prophylactically



pills SHOULD NOT BE CRUSHED OR MELTED



common side effect constipation



GIVEN QID AC AND AT BED TIME

misoprostol

used to protect gastric mucosa from long term NSAID use in patients at high risk for developing GI bleeding or peptic ulcers and geriatrics



is started at the onset of NSAID therapy



also used to terminate pregnancy of 49 days or less by causing uterine contractions



side effects are abdominal pain, diarrhea, spontaneous abortion

antidiarrheals

lopermide, diphenoxylate HCL, naopecate



direct effect on slowing peristalsis



used for acute diarrhea, chronic diarrhea associated with IBD



side effects drowsiness, dizziness, abdominal discomfort

bismuth subsalicylate

antidiarrheal adjunctive drug for treatment of h. pylori in peptic ulcer disease and to treat nausea, indigestion and diarrhea



contain aspirin - risk of reye's syndrome



is available aspirin free



alaviable OTC and come in the oral forms of suspension and tablets

bulk forming laxative

psyllium



similar to fiber, combined with fluids in GI tract to swell and form a fibrous mass with focal material. this stimulates peristalsis



side effect


impaction and bowel obstruction if not given with enough fluids



MIX RIGHT BEFORE ADMINISTERING


8 OZ OF FLUID OR JUICE


GIVE 2HR AC OT PC


GIVE WITH PLENTY OF FLUID

bisacodyl

stimulate laxative



increase peristalsis



used short term to treat constipation, Bowel prep before surgery or diagnostic tests



side effects : N,D abdominal cramping

sennosides

herb


laxative


short term tx constipation


OTC

Milk of Magnesia

osmotic laxative



draws water from surrounding blood vessels into large intestines. dilutes stool and increases peristalsis



usually given in P.M.


GIVEN WITH 8 OZ OF WATER


15 ML ANACID


30ML LAXATIVE

magnesium cirate

comes premixed in 8 oz bottle


carbonated


administer on ice makes it more palatable

ammonia detoxicant/laxative

lactulose



pulls ammonia into the intestines (liver disease) and promotes peristalsis and bowel evacuation



side effects


abdominal cramping


nursing implication


monitor serum ammonia level


may be given PO or enema

polyethyglycol

osmotic laxative



bowel cleansing preparation prior to GI examination



administer as directed



should only have CLEAR FLIUDS after administration until midnight before the day of the test then NPO

polyethylene glycol

treatment of the occasional constipation



mix in water prior to administration



may take 2-4 days for bowel movement to occur

stool softener

docusate calcium and docusate sodium



can be used daily basis to promote softening of the stool in pt who should not strain to have a BM


cardiac pt


rectal surgery



OTC usually 1 dose daily PO

prokinetic agent

metoclopramide



perstaltic stimulant


antiemetic



uses


GERD


diabetic gastroparesis give 30" ac and his


chemotherapy related N,V give 30" before tx



side effect


drowsiness, restlessness, fatigue, lethargy

megesterol

therapeutic: antineoplastic, hormone appetite stimulant



relieves some sx of advanced breast and endometrial cancer, appetite stimulant for HIV or cancer related anorexia and weight loss



? use in elderly



increased appetite and weight gain

florastor

probiotic



lactobacillus acidophilus



used to prevent C. Diff and diarrhea in ppl who are taking antibiotics

UGI or barium swallow

detects abnormalities of the stomach or esophagus



after drinking a contrast medium (barium) several xrays are taken 6 hrs later



MUST BE NPO for at least 8 hrs before the procedure

small bowel series

detects abnormalities of the small intestine



after drinking a contrast medium ( barium) xrays are taken at 20-30 min Intravels as the solution passes through the small intestine



test may take several hours



MUST BE NPO BEFORE TEST

barium enema

detect abnormalities of the large intestines



contrast solution (barium) is administered by enema and xray are taken in various positions



procedure may take 1-2 hrs

CCK/ HIDA SCAN

done in nuclear medicine



a radioactive substance (HIDA) is given IV and the substance is tracked with a scanner



used to determine the patency of the cystic and common bile ducts and the evaluate liver and gallbladder function



an injection of cholecystokinin is often injected to make the gall bladder contract and secrete bile must be NPO for several hours before test

doctors may prescribe blank along woth oral barium

laxative or enema



bc barium is constipating

endoscopic test

gastroscopy


ERCP


colonoscopy


sigmoidoscopy

gastroscopy

visualizes stomach and esophagus

ERCP

visualize common bile duct (CBD) and gallbladder

colonoscopy

visualizes colon

sigmoidoscopy

visualizes sigmoid colon and rectum

liver enzymes

AST/SGOT


ALT/SGPT



Liver enzymes often elevate w/liver disease or damage often ordered LFT


pancreatic enzymes

amylase


lipase


trypsin


often elavated with pancreas or gallbladder disease



aid in digestion

bilirubin

often elevated with liver disease, gallbladder or pancreatic disease and cause jaundice



direct


indirect


total

clotting disease

prolonged in certain disease such as liver disease and when pt is taking anticoagulants



PT


aPTT


INR

PT

use to measure thrombin



10-13 second is normal

INR

2-3 seconds normal

aPTT

normal time 25-30 seconds

CEA level

found only during fetal life or rapid multiplication of cells (CA)


Albumin

protein present in the body in the largest amounts. maintain serum colloidal osmotic pressure. decreased in many diffrent diseases

globulin

another type of protein found in the baby In smaller amounts