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  • Front
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Amfenikolers virkningsmekanisme
ligesom makrolidernes
Må man godt blande makrolider og amfenikoler?

NEJ!!!

Amfenikolers kemiske egenskaber


Alkoholer




Fedtopløselige --> penetrerer derfor membraner godt, med godt vævsfordeling.

Er amfenikoler bakteriostatiske eller baktericide?

De er bakteriostatiske

Hvordan udvikles der resistens overfor amfenikoler?


Kan ske via plasmidoverførsel, hvor der er overførsel af flere resistens på én gang. Mange plasmider bærer resistens for både kloramfenikol, sulfonamid og tetracyklin.

Hvilken amfenikol bruges primært veterinært?

Florfenicol
Hvad ved du om Colistin?


Utrolig god til colibakterier (e. coli, klebsiella og salmonella)


Koncentrationsafhængig


Bruges som en sidste udvej til pneumoni hos mennesker.





Hvad ved du om Fucisin


Den kan bruges imod MRSA


Steroid, uden hormonal virkning