Drug List 2: Moa [Pharmacology I]

Front 1

Mechanism of Action for Atropine Sulfate (a' troe peen)

Back 1

Selectively antagonizes muscarinic receptors
(limited to the peripheral effects at clinical doses)

Front 2

Mechanism of Action for Darifenicin (dar ee fen' a sin)

Back 2

Antagonist of muscarinic receptors, on glands and smooth muscles, displaying a higher selectivity for M3 receptors than for M2

Front 3

Mechanism of Action for Bethanecol Chloride (be than' e kole)

Back 3

Agonist of muscarinic receptors that is completely resistant to hydrolysis by cholinesterases and exhibits a high selectivity, relative to its affinity for nicotinic receptors.

Front 4

Mechanism of Action for Pilocarpine (pye" loe kar' peen)

Back 4

Cholinergic receptor agonist for which the muscarinic action is dominant, relative to its effect on nicotinic receptors

Front 5

Mechanism of Action for Cevimeline (se vim' e leen)

Back 5

Muscarinic receptor agonist valued for its activity on M3 - receptors of lacrimal and salivary gland epithelia

Front 6

Mechanism of Action for Scopolamine (skoe pol' a meen)

Back 6

Selectively antagonizes muscarinic receptors (crosses the BBB, leading to prominent CNS effects even at low therapeutic doses)

Front 7

Mechanism of Action for Homatropine (hoe ma' troe peen)

Back 7

Homotropine, like tropicamide, selectively antagonizes muscarinic receptors with a shorter duration of action than atropine

Front 8

Mechanism of Action for Tropicamide (troe pik' a mide)

Back 8

Tropicamide, like homatropine, selectively antagonizes muscarinic receptors with a shorter duration of action than atropine

Front 9

Mechanism of Action for Ipatropium Bromide (i pra troe' pee um)

Back 9

Selectively antagonizes muscarinic receptors more potently than atropine does and also w/o appreciable action on the CNS due to its quaternary ammonium structure, which precludes crossing of the BBB

Front 10

Mechanism of Action for Tolterodine (tole ter' a deen)

Back 10

Tolterodine, like oxybutynin, propantheline bromide, & trospium chloride, selectively antagonizes muscarinic receptors (nonspecifically w/ respect to subtype)

Front 11

Mechanism of Action for Oxybutynin (ox i byoo' ti nin)

Back 11

Oxybutynin, like propantheline bromide, tolterodine & trospium, selectively antagonizes muscarinic receptors (nonspecifically w/ respect to subtype)

Front 12

Mechanism of Action for Trospium Chloride (trose' pee um)

Back 12

Trospium, like oxybutynin, propantheline bromide, & tolterodine, selectively antagonizes muscarinic receptors (nonspecifically w/ respect to subtype)

Front 13

Mechanism of Action for Solifenacin (sol i fen' a cin)

Back 13

Selectively antagonizes M3 receptors specifically

Front 14

Mechanism of Action for Flavoxate (fla vox' ate)

Back 14

Selectively antagonizes muscarinic receptors

Front 15

Mechanism of Action for Hyoscyamine (hye oh sye' a meen)

Back 15

Selectively antagonizes muscarinic receptors

Front 16

Mechanism of Action for Benztropine (benz' troe peen)

Back 16

Selectively antagonizes muscarinic receptors

Front 17

Mechanism of Action for Trihexyphenidyl (trye hex ee fen' i dil)

Back 17

Selectively antagonizes muscarinic receptors

Front 18

Mechanism of Action for Glycopyrrolate (glye koe pye' roe late)

Back 18

Selectively antagonizes muscarinic receptors

Front 19

Mechanism of Action for Methscopolamine Bromide (meth' skoe pol' a meen)

Back 19

Quaternary ammonium derivative of scopolamine that also selectively antagonizes muscarinic receptors w/o the CNS actions of scopolamine

Front 20

Mechanism of Action for Tiotropium Bromide (tee oh tro' pee um)

Back 20

Specifically antagonizes muscarinic receptors showing some selectivity for M1 and M3 subtypes. Its quaternary structure precludes crossing of the BBB

Front 21

Mechanism of Action for Methacholine Chloride (meth ah koh' leen)

Back 21

Muscarinic receptor agonist having relative selectivity for cardiovascular muscarinic receptors

Front 22

Mechanism of Action for Dicyclomine (dye sye' kloe meen)

Back 22

Selectively antagonizes muscarinic receptors

Front 23

Mechanism of Action for Acetylcholine (uh see' till koh' leen)

Back 23

Stimulates muscarinic receptor activity

Front 24

Mechanism of Action for Metoclopramide (met oh kloe pra' mide)

Back 24

Exhibits combined cholinergic agonist and dopamine antagonist activity

Front 25

Mechanism of Action for Propantheline Bromide (proe pan' the leen)

Back 25

Propantheline bromide, like oxybutynin, tolterodine, & trospium chloride, selectively antagonizes muscarinic receptors (nonspecifically w/ respect to subtype)

Front 26

Mechanism of Action for Mepenzolate Bromide (me pen' zoe late)

Back 26

Quaternary amine having peripheral actions similar to those of atropine
(selectively antagonizing muscarinic receptors)

Front 27

Mechanism of Action for Carbacol Chloride (kar' ba kall)

Back 27

Muscarinic agonist that is completely resistant to hydrolysis by cholinesterases and retains substantial activity on neuronal-type nicotinic receptors.