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Dopamine
An inhibitory neurotransmitter. Maintains control of acetylcholine and inhibits it's excitatory response.
Acetylcholine
An excitatory neurotransmitter.
What happens when you have an increased stimulation GABA in Parkinsons disease?
Symptomatic movement disorders occur
Treatment regimen for Parkinsonism "Anticholinergics"
Block cholinergic receptors
X
Treatment regimen "dopaminergics"
Convert to dopamine (which increases mobility)
->
Treatment regimen "dopamine agonists"
Stimulate dopamine receptors
Sts
Treatment regimen "MAO-B inhibitors"
Inhibit MAO-B enzyme that interferes with dopamine
/
Treatment regimen "COMT inhibitors"
Inhibit COMT enzyme that inactivates dopamine
Anticholinergics are sympatholytics or parasympatholytics?
Parasympatholytics
Examples of anticholinergics
Benzotropine (Cogentin)
Trihexyphenidyl HCL (Artane)
Biperiden (Akineton)
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