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How do nitrates improve cardiac symptoms
Nitrates increase the production of nitric oxide, which is responsible for relaxing the smooth muscle of blood vessels.
3 types of nitrate vasodilators
Glceryl trinitrate (100% metabolized in liver - cannot be given orally)
Isorbide mononitrate
Isorbide trinitrate
What are calcium channel blockers (CCBs) and what are the side effects
CCBs block calcium channels, preventing arterial contraction (instead causing vasodilation) thereby reducing blood pressure and cardiac demand and AFTER-LOAD
Side effects: oedema, hypotension, dizziness, tachycardia and bradycardia
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