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what are the 5 characteristics of inflammation
rubor - redness
calor - heat
tumor - swelling
dollor - pain
functio laesa - loss of function
what does it mean if something is septic e.g. septic arthiritis
(chiefly of a wound or a part of the body) infected with bacteria: his feet had gone septic.
what are the characteristics of septic arthritis in terms of bacteria
Staphylococcus aureus
Secreted enzymes toxins
Rapid reproduction
Tissue destruction
what is the response of neutrophils to bacteria
neutrophils hold an arsenal of anti-bacterial factors
how do neutrophils get from the blood stream to the site where they are needed
what is the process called by which a neutrophil will cross the blood vessel wall to get to the site of infection
diapedesis
neutrophils are an important component of the innate immune system, what conditions are required for neutrophils to work
-Detection of the threat – bacteria
-Response – make more neutrophils
-Response – get the neutrophils to the site of infection
how does the body recognise a pathogen
through the PRR (pattern recognition receptor)
what do pathogens possess which allows the innate immune system to recognise them
PAMPs (pathogen associated molecular patterns)
what event actually initiates the response in the immune system to a pathogen
when the receptor interacts with a ligand
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