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13 Cards in this Set
- Front
- Back
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what are the non modifiable risk factors of AD? what are the modifiable risk factors AD? |
age, female, family history, genetics head injury, low education, elevated blood pressure, high cholersterol, diabetes, physical inactivity, obesity, smoking (stupid and fat) |
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what are signs of AD that are also signs of depression? what test is given to determine AD? |
withdrawal from work and social activities, changes in behavior, mood, and personality mini mental state examination (mmse) |
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what numbers are mild on the mmse? moderate? severe? what is the first thing you should look to do when treating an AD patient? |
26-18 17-10 9-0 decrease polypharmacy |
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what are some nonpharmacological things to consider AD? is there a difference in efficacy among the cholinesterase inhibitors? what cholinesterase was taken of the market? brand/generic? |
avoid confrontation, remain calm, use frequent reminders, physcial activity, social engagment, cognitive enhancing activities no, they are all equivalent tacrine/cognex...from hepatotoxicity |
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donezapil dosing for mild to moderate? dosing moderate to severe? what is the highest dose? how long until you can give it? |
5 mg po hs 5 mg qd hs, titrate to 10 mg 4-6 weeks 23 mg, after 3 months |
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dose limiting side effect of all the cholinesterase inhibitors? is donezapil protein bound? what should you monitor? |
bradycardia, watch pulse under 60 bpm 96% pulse, mmse, bi bleeding |
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rivastimgmine oral dosing for mild to moderate? patch dose for mild moderate and severe? what is the patch dose if child pugh is 5-9? low body weight? high body weight? |
1.5 mg po bid wf, increase by 3 mg qd every 2 weeks 9.5 mg/day, titrate to 18.5 mg/qd after 4 weeks 4.6 mg/qd 4.6 mg/qd 9.5 mg/qd |
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if your dose of oral rivastigmine was less than 6 mg per day, what patch dose would you use? what if the oral dose was 6-12? |
4.6 mg/qd 9.5 mg/qd increasese to 18.5 after 4 weeks |
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could you use galantamine for severe ad? what is the dosing for galantamine? razadyne IR ER? do you ever have to do dose adjustment? |
no, only mild to moderate 4 mg PO BID for 4 weeks, then 8 mg po bid for 4 weeks, then 12 po bid 8 mg po qd for 4 weeks, 16 mg po qd for 4 weeks, 24 mg po qd for renal and hepatic failure |
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what type of ad is memantine used in? what is the max dose if creatinine clearance is below 30 ml/min IR? ER? |
moderate to severe 5 mg po bid 14 mg po qd |
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what is the name of the combination product? when is the only time this is reccomended? |
namzaric (donepezil and memantine) only reccomended when donepezil is maxed out |
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when should you consider stop using ad medications? |
terminally ill, loss of adls, severe psychosis, average decline in mmse 3.3 per year |
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done for now |
done for now |
