Chapter 21

Front 1

Gamma Gobulin portion of blood// Gamma globulins are a class of ____________ in the blood// This gamma gobulin portion in blood is an ___________.

Back 1

Immunoglobulins// proteins// antibody

Front 2

anti_________ are ____________ secreted by p_________ c__________ in response to an an________.

Back 2

antibodies are proteins secreted by plasma cells in response to an antigen.

Front 3

________________ are capable of binding specifically with antigen d___________d by __ cells.

Back 3

antibodies are capable of binding specifically with antigens detected by B cells

Front 4

How many classes of Antigens are they and what are the names of the classes?

Back 4

5; (Igm,IgA,IgD,IgG or IgE)

Front 5

T or Y shaped monomer of f_____looping linked poly________ chains.

How many (H) chains? Are these different or identical?
How many (L) chains? identical or different

Each chain has a ___________(V) region and a much larger ___________ ( ) region

______________ (V) regions determine antigen __________; on each arm they combine to form an a___________-b___________ site.

Back 5

four; poly; 2; identical; 2 identical; variable; constant (C); variable; specificity; antigen binding site

Front 6

Constant (C) region of s____m determines 1) & 2)

Back 6

antibody class and common functions; function includes the cells and chemicals of the body the antibody can bind to; how the antibody class functions in antigen elimination

Front 7

Pentamer; first antibody released (useful for diagnosis); monomer is an antigen receptor in B cells

Back 7

IgM

Front 8

Monomer or dimer; in saliva, sweat, mucus and other secretions. It plays a major role in preventing pathogens from gaining entry into the body.

Back 8

IgA- secretory IgA

Front 9

What is the main antibody defense against cellular antigens?

Back 9

Complement Fixation and Activation

Front 10

- several antibodies bind close together on a cellular antigen
-their complement-binding sites trigger complement fixation into the cell's surface
- complement triggers cell lysis

Back 10

Complement Fixation and Activation

Front 11

__-cells provide defense against intracellular antigens

Back 11

T

Front 12

There are ___ types of s_______ receptors of T cells: They are AR & DG

Back 12

2; surface; Antigen receptors (t-cell); differentiation glycoproteins (CD4 or CD8)

Front 13

Differentiation Glycoproteins play a role in __- celll int________ with o______ ce__; 2 types:

Back 13

t-cell interaction w/ other cells. CD4 & CD8

Front 14

Major Types of T-cells produce what?

Back 14

A cell-mediated immune response

Front 15

CD4 cells become ________ _____ when activated

Back 15

helper T cells

Front 16

CD8 cells become _______________ that destory cells harboring foreign antigens

Back 16

cytotoxic

Front 17

"other types of T cells" - other than CD4 and CD8?

Back 17

regulatory T cells and Memory T cells

Front 18

Lymphocytes that destroy cancerous cells in a non-specific fashion are called

Back 18

NK cells

Front 19

Which of the following is a specific body defense mechanism

Phagocytosis.
inflammation
immunity
fever

Back 19

immunity

Front 20

The most abundant type of immunoglobin is

Back 20

IgG

Front 21

Interferon is produced in response to the presence of

Back 21

viruses

Front 22

The two major types of phagocytic cells are

Back 22

neutrophils and lympocytes

Front 23

The antibodies involved in allergic reactions are

Back 23

.
in the IgE class

Front 24

Normal immune responses require the presence of

Back 24

T lymphocytes and B lymphocytes

Front 25

Which of the following cell types is derived from monocytes?

Back 25

wandering macrophage

Front 26

Natural killer cells are


monocytes
macrophages
lymphocytes
neutrophils

Back 26

lymphocytes

Front 27

A hapten is an antigen that has
r____________y but not immun__geni_____

Back 27

reactivity but not immunogenicity

Front 28

The structure of a lymphatic vessel is most similar to that of a(n)

Back 28

.
vein

Front 29

Afferent lymph vessels c_______ lymph toward _____________ _____________

Back 29

carry lymph toward lymph nodes

Front 30

chemotactic and attracts phagocytic cells

Back 30

Complement

Front 31

.
are responsible for antibody-mediated immunity

Back 31

B lymphocytes

Front 32

Medullary sinuses of lymph nodes are filled w/

Back 32

lymph

Front 33

Antigen recognition by a T-cell receptor with CD4 or CD8 proteins is the
________ in the activation of a T-cell.

Back 33

1st signal

Front 34

Lack of reactivity of T cells and B cells to fragments of one's own proteins is known as

Back 34

self-tolerance

Front 35

Lymph from the cisterna chyli empties into the

Back 35

thoracic duct

Front 36

The proper sequence of phases in the process of phagocytosis is

Back 36

chemotaxis, adherence, ingestion

Front 37

vasodilation and increased permeability of blood vessels

Back 37

The first stage of inflammation is

Front 38

mark the surfaces of all your body cells except your red blood cells

Back 38

Class I major histocompatibility complex (MHCI) antigens

Front 39

Antigen presenting cells (APCs) include

macrophages

killer T cells

neutrophils

plasma cell

Back 39

macrophages

Front 40

perforin and granulysin

Back 40

Cytotoxic T cells can kill target cells directly by secreting