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29 Cards in this Set
- Front
- Back
The citric acid cycle operates where?
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mitochondria
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Coupled with electron transport, citric acid cycle is the major source of what?
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ATP
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Pyruvate enters into the mitochondria via what
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pyruvate translocase
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pyruvate is transformed into what via pyruvate dehydrogenase complex
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aectyl CoA
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What enzyme uses cofactor of thiamine pyrophosphate (TPP)
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pyruvate dehydrogenase
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the cofactor lipoamide uses what enzyme
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dihydrolipoamide acetyltransferase
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Enzyme 3, dihydrolipoamide dehydrogenase uses the cofactor what?
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flavin adenine dinucleotide (FAD)
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Reaction 1 of pyruvate dehydrogenase complex does what
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decarboxylation and transfer of hydroxyethyl group
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The step 2 of reaction 1 functions as oxidation of hydroxyethyl TPP and transfer to what
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lipoamide
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The reaction catalyzed by E2 which is what, functions to transfer of acetyl CoA group to coenzyme A to form what?
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dihydrolipoamide acetyltransferase to form acetyl coA
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Reaction catalyzed by E3 which is what, functions as oxidation of what by E3-FAD
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dihydrolipoamide dehydrogenase functions as oxidation of dihydrolipoamide
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The regeneration of E3-FAD has E3-FADH2 plus NAD+ forms what
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E3-FAD + NADH + H+
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What functions as a swinging arm in PDC
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E2-lipoamide
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all enzymes exept for what are in the mitochondrial matrix for citric acid cycle
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succinic dehydrogenase
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Acetyl CoA enters the citric acid cylce via what
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citrate
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oxaloacetate plus acetyl CoA forms citrate via what enzyme
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citrate synthase
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Aconitase converts citrate to what
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isocitrate
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oxidate decarboxylation of isocitrate forms what via what enzyme
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forms ketoglutarate via isocitrate dehydrogenase
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ketoglutarate forms succinyl CoA via what complex
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Ketoglutarate dehydrogenase complex
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Succinyl CoA synthetase makes what and forms what
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forms succinate; makes GTP
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Succinyl CoA sythetase makes GTP is an example of what
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substrate level phosphorylation
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Succinate to fumarate reaction is done by what complex
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succinic dehydrogenase reaction
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The fumarase reaction alters fumarate to whate
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malate
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malate to oxaloacetate is formed by what enzyme
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malate dehydrogenase
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The total ATP molecules formed by glycolysis and citric acid cycle is what
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32 ATP
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How many ATP equivalent moleculues are formed by substrate level phsophorylation
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4
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how many ATP equivalent molecules are formed by oxidative phosphorylation
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28
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regulation from pyruvate to acetyl CoA in citric acid cycle is negative from what and positive from what?
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negatively regulated by NADH and Acetyl CoA
positively regulated by HS-CoA and NAD+ |
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Isocitrate to ketoglutarate regulated negatively by what and postively by what
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regulated negatively by NADH and positively by ADP and Ca2+
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