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114 Cards in this Set

  • Front
  • Back
What are the Sx's of Giardia lamblia infection?
Bloating
Flatulence
Foul-Smelling Diarrhea
Tx of Giardia?
Cysts in Water
Dx of Giardia?
Trophozoites or cysts in stool
Rx for Giardia?
Metronidazole
Tx of Trichomonas vaginalis?
Sexual
Rx for Trichomonas vaginalis?
Metronidazole
What causes Chagas' Disease? Sx's?
Trypanosoma cruzi

dilated cardiomyopathy
megacolon
megaesophagus
Where do you normally see Trypanosoma cruzi?
South America
Tx of Trypanosoma cruzi?
Reduviid Bug aka kissing bug
Dx of Trypansoma cruzi?
blood smear
Rx for Trypanosoma cruzi?
Nifurtimox
What causes African Sleeping Sickness?
Trypanosoma gambiense or rhodesiense
Sx's of T. gambiense or rhodesiense?
Enlarged LN's
Recurring Fever
Somnolence
Coma
Tx of T. gambiense or rhodesiense?
Tsetse fly
Rx for T. gambiense or rhodesiense?
Suramin for blood-borne disease
Melarsoprol for CNS penetration
What does Leishmania donovani cause? sx's?
Visceral Leishmaniasis
Spiking Fevers
Hepatosplenomegaly
Pancytopenia
Tx of Leishmania donovani?
Sandfly
Dx of Leishmania donovani?
Macrophages containing AMASTIGOTES
Rx for Leishmania donovani?
Sodium stibogluconate
Types of Malaria bugs?
Plasmodium:
vivax
ovale
malariae
falciparum
Sx's of Malaria?
Cyclic Fever
HA
Anemia
Splenomegaly
Who is the most serious malaria bug?
P. falciparum
Who can cause relapsing malaria?
P. vivax and ovale

they lie dormant in liver
Tx of malaria?
Mosquito (anopheles)
Rx for Malaria?
Chloroquine
(primaquine to prevent relapse)
Sulfdoxine + Pyrimethamine
Mefloquine
Quinine
Kicker histo appearance of Plasmodium?
Trophozoite ring form in RBC
What does Babesia cause? sx's?
Babesiosis
Fever
Hemolytic Anemia
Where do most Babesia infections occur?
Northeastern US
Tx of Babesia?
Ixodes Tick
Dx of Babesia?
Blood Smear
no RBC pigment
RBC appears as Maltese Cross
Rx for Babesia?
Quinine
Clindamycin
What does Cryptosporidium cause?
Mild disease (watery poo) in healthy pts
Severe Diarrhea in AIDS
Tx of cryptosporidium?
cysts in water
Dx of Cryptosporidium?
Acid-Fast cysts show up w/ stain
Rx for Cryptosporidium?
NONE
What does Toxoplasma gondii cause?
Brain abscess in HIV
Birth defects in fetuses (ring-enhancing brain lesions)
Tx of Toxo?
Cysts in meat or cat poo

cross placenta
Rx for Toxo?
Sulfadiazine + Pyrimethamine
What does Entamoeba histolytica cause?
Bloody Diarrhea
dysentery
Liver Abscess
RUQ pain
Tx of Entamoeba histolytica?
Cysts in water
Histo appearance of E. histolytica?
RBC's in cytoplasm of trophozoites
Cyst w/ 4 nuclei
Rx for Entamoeba histolytica?
Metronidazole and Iodoquinol
What does Naegleria fowleri cause?
Rapidly fatal meningoencephalitis
Tx of Naegleria fowleri?
Swimming in fresh water lakes (enter via cribiform plate)
Dx of Naegleria fowleri?
Amoebas in CSF
Rx for Naegleria fowleri?
NONE
Who is the Pinworm?
Enterobius vermicularis
Enterobius Vermicularis
Tx and Disease
From food contaminated w/ eggs
Intestinal infection
Anal Pruritis
Test for E. vermicularis?
Scotch Tape Test of anus
Rx. for Pinworm (E. vermicularis)?
Mebendazole
or
Pyrantel Pamoate
Who is the Giant Roundworm?
Ascaris lumbricoides
Ascaris lumbricoides
Disease and Dx?
Intestinal infection
Eggs visible in feces
Rx for Ascaris lumbricoides?
Mebendazole
or
Pyrantel Pamoate
Who is the Pork worm?
Trichinella spiralis
Trichinella spiralis
Tx and Sx's?
Undercooked meat, usually pork
Inflammation of muscle (larvae encyst in musc)
Periorbital Edema
Rx for Trichinella spiralis?
Thiabendazole
Tx and Sx's of Strongyloides stercoralis?
Larvae in soil penetrate skin
Intestinal infection w/ vomiting, diarrhea, and anemia
Rx for Strongyloides stercoralis?
Ivermectin
or
Thiabendazole
Who are the hookworms?
Ancylostoma duodenale
Necator americanus
Tx and Sx's for Hookworms?
Larvae penetrate skin of feet
Intestinal infection can cause anemia (suck blood from intestinal walls)
Rx for Hookworms?
Mebendazole
or
Pyrantel Pamoate
Tx and Sx's of Dracunculus medinensis?
Drinking water
Skin inflammation and ulceration
Rx for Dracunculus medinensis?
Niridazole
Onchocerca volvulus
Tx and Disease
Female blackflies
Causes River Blindness w/ skin nodules and lizard skin.
Can have allergic rxn to microfilaria
Rx for Onchocerca volvulus?
Ivermectin
Loa Loa
Tx and Sx's?
Deer fly, Horse fly, mango fly
Swelling in skin (can see worm crawling in conjunctiva
Rx for Loa Loa?
Diethylcarbamazine
Who causes elephantiasis?
Wuchereria bancrofti
Tx and Sx's of wuchereria bancrofti?
Female Mosquito
Blockage of lymphatics
Takes 9-12 months after bite to get elephantiasis
Rx for Wuchereria bancrofti?
Diethylcarbamazine
Who is the Dog Roundworm?
Toxocara canis
Tx and Sx's of Toxocara canis?
food contaminated w/ eggs
Causes granulomas and visceral larva migrans

Granuloma in retina can --> blindness
Rx for Toxocara canis?
Diethylcarbamazine
Who are the tapeworms?
Taenia solium
Diphyllobothrium latum
Echinococcus granulosus
Who is the Pork Tapeworm?
Taenia solium
Tx of Taenia solium?
Ingestion of larvae from undercooked pork--->intestinal tapeworms
Disease and Sx's from Taenia solium?
Ingestion of eggs--->cysticercosis and neurocysticercosis, i.e. mass lesions in brain (swiss cheese)
Rx for Taenia solium?
Praziquantel for intestinal worms and cysticercosis

Albendazole for neurocysticercosis
How do you get Diphyllobothrium latum?
Ingest larvae in raw freshwater fish
What does Diphyllobothrium latum do to you?
Causes B12 def--->anemia
Rx for Diphyllobothrium latum?
Praziquantel
what is the Hydatid Worm?
Echinococcus granulosus
Tx, pathogenesis, and sx's of Echinococcus granulosus?
Eggs in dog poop get ingested-->cysts in liver

If echinococcal Ag's are released from cysts--->anaphylaxis
Rx for Echinococcus granulosus?
Albendazole
Who are the Flukes?
TREMATODES
Schistosoma
Clonorchis sinensis
Paragonimus westermani
Tx of Schistosoma?
Snails are the hosts
Cercariae penetrate our skin
Disease and Sx's of Schistosoma?
Granulomas, fibrosis, and inflammation of Spleen and Liver
What is special about Schistosoma haematobium?
a chronic infection can lead to squamous cell carcinoma of the bladder
Rx for Schistosoma?
Praziquantel
Tx of Clonorchis sinensis?
Undercooked fish
Disease, Sx's and Ass. of Clonorchis sinensis?
Causes inflammation of biliary tract-->pigmented gallstones

Associated w/ cholangiocarcinoma
Rx for Clonorchis sinensis?
Praziquantel
Tx of Paragonimus westermani?
Undercooked crab meat
Disease/Sx's of Paragonimus westermani?
Inflammation and secondary bacterial infection of lungs
Rx for Paragonimus westermani?
Praziquantel
Who does Mebendazole/Pyrantel Pamoate kill?
Enterobius vermicularis
Ascaris lumbricoides
Ancylostoma duodenale
Necator americanus
Who does Thiabendazole kill?
Trichinella spiralis
Strongyloides stercoralis
Who does Ivermectin kill?
Strongyloides stercoralis
Onchocerca volvulus
Who does Diethylcarbamazine kill?
Loa loa
Wuchereria bancrofti
Toxocara canis
Who does Albendazole kill?
Echinococcus granulosus
Taenia solium's neurocysticercosis
Who does Praziquantel kill?
Intestinal Taenia solium
Diphyllobothrium latum
All the Flukes:
Schistosoma
Clonorchis sinensis
Paragonimus westermani
Who are the nematodes that have to be ingested vs those that get in via skin?
Ingested: Enterobius, Ascaris, Trichinella (EAT)

Cutaneous: Strongyloides, Ancylostoma, Necator (SANd)
If I say ______, you say _____
Brain cysts, seizures?
Taenia solium (cysticercosis)
If I say ______, you say _____
Liver cysts?
Echinococcus granulosus
If I say ______, you say _____
B12 Def?
Diphyllobothrium latum
If I say ______, you say _____.
Biliary Tract Disease?
Clonorchis sinensis
If I say ______, you say _____.
Hemoptysis?
Paragonimus westermani
If I say ______, you say _____.
Portal HTN?
Schistosoma mansoni
If I say ______, you say _____.
Hematuria, bladder cancer?
Schistosoma haematobium
If I say ______, you say _____.
Microcytic anemia?
Ancylostoma, Necator
Perianal pruritis?
Enterobius
The Tricky T's of Micro?
Typhoid fever vs Typhus
Typhoid Fever = Salmonella typhi
Typhus = Rickettsia prowazekii (epidemic), Rickettsia typhi (endemic), Rickettsia tsutsugamushi (scrub typhus)
The Tricky T's of Micro?
the STD's
Chlamydia trachomatis (bacteria, STD)
Treponema (spirochete, syphilis or yaws)
Trichomonas vaginalis: protozoan, STD
The Tricky T's of Micro?
The other 3?
Trypanosoma (protozoan, Chagas' (cruzi) or African Sleeping Sickness
Toxoplasma: protozoan, TORCH
Trichinella spiralis: nematode, undercooked meat