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114 Cards in this Set
- Front
- Back
What are the Sx's of Giardia lamblia infection?
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Bloating
Flatulence Foul-Smelling Diarrhea |
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Tx of Giardia?
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Cysts in Water
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Dx of Giardia?
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Trophozoites or cysts in stool
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Rx for Giardia?
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Metronidazole
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Tx of Trichomonas vaginalis?
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Sexual
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Rx for Trichomonas vaginalis?
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Metronidazole
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What causes Chagas' Disease? Sx's?
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Trypanosoma cruzi
dilated cardiomyopathy megacolon megaesophagus |
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Where do you normally see Trypanosoma cruzi?
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South America
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Tx of Trypanosoma cruzi?
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Reduviid Bug aka kissing bug
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Dx of Trypansoma cruzi?
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blood smear
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Rx for Trypanosoma cruzi?
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Nifurtimox
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What causes African Sleeping Sickness?
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Trypanosoma gambiense or rhodesiense
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Sx's of T. gambiense or rhodesiense?
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Enlarged LN's
Recurring Fever Somnolence Coma |
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Tx of T. gambiense or rhodesiense?
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Tsetse fly
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Rx for T. gambiense or rhodesiense?
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Suramin for blood-borne disease
Melarsoprol for CNS penetration |
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What does Leishmania donovani cause? sx's?
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Visceral Leishmaniasis
Spiking Fevers Hepatosplenomegaly Pancytopenia |
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Tx of Leishmania donovani?
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Sandfly
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Dx of Leishmania donovani?
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Macrophages containing AMASTIGOTES
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Rx for Leishmania donovani?
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Sodium stibogluconate
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Types of Malaria bugs?
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Plasmodium:
vivax ovale malariae falciparum |
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Sx's of Malaria?
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Cyclic Fever
HA Anemia Splenomegaly |
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Who is the most serious malaria bug?
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P. falciparum
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Who can cause relapsing malaria?
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P. vivax and ovale
they lie dormant in liver |
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Tx of malaria?
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Mosquito (anopheles)
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Rx for Malaria?
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Chloroquine
(primaquine to prevent relapse) Sulfdoxine + Pyrimethamine Mefloquine Quinine |
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Kicker histo appearance of Plasmodium?
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Trophozoite ring form in RBC
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What does Babesia cause? sx's?
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Babesiosis
Fever Hemolytic Anemia |
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Where do most Babesia infections occur?
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Northeastern US
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Tx of Babesia?
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Ixodes Tick
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Dx of Babesia?
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Blood Smear
no RBC pigment RBC appears as Maltese Cross |
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Rx for Babesia?
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Quinine
Clindamycin |
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What does Cryptosporidium cause?
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Mild disease (watery poo) in healthy pts
Severe Diarrhea in AIDS |
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Tx of cryptosporidium?
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cysts in water
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Dx of Cryptosporidium?
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Acid-Fast cysts show up w/ stain
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Rx for Cryptosporidium?
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NONE
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What does Toxoplasma gondii cause?
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Brain abscess in HIV
Birth defects in fetuses (ring-enhancing brain lesions) |
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Tx of Toxo?
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Cysts in meat or cat poo
cross placenta |
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Rx for Toxo?
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Sulfadiazine + Pyrimethamine
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What does Entamoeba histolytica cause?
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Bloody Diarrhea
dysentery Liver Abscess RUQ pain |
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Tx of Entamoeba histolytica?
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Cysts in water
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Histo appearance of E. histolytica?
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RBC's in cytoplasm of trophozoites
Cyst w/ 4 nuclei |
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Rx for Entamoeba histolytica?
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Metronidazole and Iodoquinol
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What does Naegleria fowleri cause?
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Rapidly fatal meningoencephalitis
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Tx of Naegleria fowleri?
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Swimming in fresh water lakes (enter via cribiform plate)
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Dx of Naegleria fowleri?
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Amoebas in CSF
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Rx for Naegleria fowleri?
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NONE
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Who is the Pinworm?
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Enterobius vermicularis
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Enterobius Vermicularis
Tx and Disease |
From food contaminated w/ eggs
Intestinal infection Anal Pruritis |
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Test for E. vermicularis?
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Scotch Tape Test of anus
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Rx. for Pinworm (E. vermicularis)?
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Mebendazole
or Pyrantel Pamoate |
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Who is the Giant Roundworm?
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Ascaris lumbricoides
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Ascaris lumbricoides
Disease and Dx? |
Intestinal infection
Eggs visible in feces |
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Rx for Ascaris lumbricoides?
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Mebendazole
or Pyrantel Pamoate |
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Who is the Pork worm?
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Trichinella spiralis
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Trichinella spiralis
Tx and Sx's? |
Undercooked meat, usually pork
Inflammation of muscle (larvae encyst in musc) Periorbital Edema |
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Rx for Trichinella spiralis?
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Thiabendazole
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Tx and Sx's of Strongyloides stercoralis?
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Larvae in soil penetrate skin
Intestinal infection w/ vomiting, diarrhea, and anemia |
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Rx for Strongyloides stercoralis?
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Ivermectin
or Thiabendazole |
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Who are the hookworms?
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Ancylostoma duodenale
Necator americanus |
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Tx and Sx's for Hookworms?
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Larvae penetrate skin of feet
Intestinal infection can cause anemia (suck blood from intestinal walls) |
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Rx for Hookworms?
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Mebendazole
or Pyrantel Pamoate |
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Tx and Sx's of Dracunculus medinensis?
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Drinking water
Skin inflammation and ulceration |
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Rx for Dracunculus medinensis?
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Niridazole
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Onchocerca volvulus
Tx and Disease |
Female blackflies
Causes River Blindness w/ skin nodules and lizard skin. Can have allergic rxn to microfilaria |
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Rx for Onchocerca volvulus?
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Ivermectin
|
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Loa Loa
Tx and Sx's? |
Deer fly, Horse fly, mango fly
Swelling in skin (can see worm crawling in conjunctiva |
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Rx for Loa Loa?
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Diethylcarbamazine
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Who causes elephantiasis?
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Wuchereria bancrofti
|
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Tx and Sx's of wuchereria bancrofti?
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Female Mosquito
Blockage of lymphatics Takes 9-12 months after bite to get elephantiasis |
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Rx for Wuchereria bancrofti?
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Diethylcarbamazine
|
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Who is the Dog Roundworm?
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Toxocara canis
|
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Tx and Sx's of Toxocara canis?
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food contaminated w/ eggs
Causes granulomas and visceral larva migrans Granuloma in retina can --> blindness |
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Rx for Toxocara canis?
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Diethylcarbamazine
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Who are the tapeworms?
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Taenia solium
Diphyllobothrium latum Echinococcus granulosus |
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Who is the Pork Tapeworm?
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Taenia solium
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Tx of Taenia solium?
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Ingestion of larvae from undercooked pork--->intestinal tapeworms
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Disease and Sx's from Taenia solium?
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Ingestion of eggs--->cysticercosis and neurocysticercosis, i.e. mass lesions in brain (swiss cheese)
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Rx for Taenia solium?
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Praziquantel for intestinal worms and cysticercosis
Albendazole for neurocysticercosis |
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How do you get Diphyllobothrium latum?
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Ingest larvae in raw freshwater fish
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What does Diphyllobothrium latum do to you?
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Causes B12 def--->anemia
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Rx for Diphyllobothrium latum?
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Praziquantel
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what is the Hydatid Worm?
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Echinococcus granulosus
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Tx, pathogenesis, and sx's of Echinococcus granulosus?
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Eggs in dog poop get ingested-->cysts in liver
If echinococcal Ag's are released from cysts--->anaphylaxis |
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Rx for Echinococcus granulosus?
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Albendazole
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Who are the Flukes?
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TREMATODES
Schistosoma Clonorchis sinensis Paragonimus westermani |
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Tx of Schistosoma?
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Snails are the hosts
Cercariae penetrate our skin |
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Disease and Sx's of Schistosoma?
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Granulomas, fibrosis, and inflammation of Spleen and Liver
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What is special about Schistosoma haematobium?
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a chronic infection can lead to squamous cell carcinoma of the bladder
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Rx for Schistosoma?
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Praziquantel
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Tx of Clonorchis sinensis?
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Undercooked fish
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Disease, Sx's and Ass. of Clonorchis sinensis?
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Causes inflammation of biliary tract-->pigmented gallstones
Associated w/ cholangiocarcinoma |
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Rx for Clonorchis sinensis?
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Praziquantel
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Tx of Paragonimus westermani?
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Undercooked crab meat
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Disease/Sx's of Paragonimus westermani?
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Inflammation and secondary bacterial infection of lungs
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Rx for Paragonimus westermani?
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Praziquantel
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Who does Mebendazole/Pyrantel Pamoate kill?
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Enterobius vermicularis
Ascaris lumbricoides Ancylostoma duodenale Necator americanus |
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Who does Thiabendazole kill?
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Trichinella spiralis
Strongyloides stercoralis |
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Who does Ivermectin kill?
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Strongyloides stercoralis
Onchocerca volvulus |
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Who does Diethylcarbamazine kill?
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Loa loa
Wuchereria bancrofti Toxocara canis |
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Who does Albendazole kill?
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Echinococcus granulosus
Taenia solium's neurocysticercosis |
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Who does Praziquantel kill?
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Intestinal Taenia solium
Diphyllobothrium latum All the Flukes: Schistosoma Clonorchis sinensis Paragonimus westermani |
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Who are the nematodes that have to be ingested vs those that get in via skin?
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Ingested: Enterobius, Ascaris, Trichinella (EAT)
Cutaneous: Strongyloides, Ancylostoma, Necator (SANd) |
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If I say ______, you say _____
Brain cysts, seizures? |
Taenia solium (cysticercosis)
|
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If I say ______, you say _____
Liver cysts? |
Echinococcus granulosus
|
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If I say ______, you say _____
B12 Def? |
Diphyllobothrium latum
|
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If I say ______, you say _____.
Biliary Tract Disease? |
Clonorchis sinensis
|
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If I say ______, you say _____.
Hemoptysis? |
Paragonimus westermani
|
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If I say ______, you say _____.
Portal HTN? |
Schistosoma mansoni
|
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If I say ______, you say _____.
Hematuria, bladder cancer? |
Schistosoma haematobium
|
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If I say ______, you say _____.
Microcytic anemia? |
Ancylostoma, Necator
|
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Perianal pruritis?
|
Enterobius
|
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The Tricky T's of Micro?
Typhoid fever vs Typhus |
Typhoid Fever = Salmonella typhi
Typhus = Rickettsia prowazekii (epidemic), Rickettsia typhi (endemic), Rickettsia tsutsugamushi (scrub typhus) |
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The Tricky T's of Micro?
the STD's |
Chlamydia trachomatis (bacteria, STD)
Treponema (spirochete, syphilis or yaws) Trichomonas vaginalis: protozoan, STD |
|
The Tricky T's of Micro?
The other 3? |
Trypanosoma (protozoan, Chagas' (cruzi) or African Sleeping Sickness
Toxoplasma: protozoan, TORCH Trichinella spiralis: nematode, undercooked meat |