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11 Cards in this Set

  • Front
  • Back

Complex 1

NADH dehydrogenase CoQ oxidoreductase

Complex 2

Succinate dehydrogenase CoQ oxidoreductase

Complex 3

CoQ cytochrome c reductase

Complex 4

Cytochrome oxidase

Complex 5

ATP synthase

Inhibitors

1. Inhibitors of individual complexes


2. Inhibitors of oxidative phosphorylation


3. Uncouplers of oxidative phosphorylation

Complex 1 inhibitors

Rotenone (fish poison)


Piercidine (antibiotic)


Amobarbitol

Complex 2 inhibitors

Malonate

Complex 3 inhibitors

Antimycin (antibiotic)


Dimer caprol (drug for heavy metal poisoning)

Complex 4 inhibitors

Azide, CO, cyanide, H2S

Substrate level phosphorylation

- Energy from a high energy compound is directly transferred to nucleoside diphosphate to form a triphosphate without the help of ETC.