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6 Cards in this Set
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Pyruvate Dehydrogenase complex E1- name its major reactants, products, cofactors and regulators
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Reactant: pyruvate
Product: 2C pyruvate fragment Cofactor: thiamine pyrophosphate (prosthetic) Regulation: Phosphorylation (deactivated by PDH kinase/activated by PDH phophotase) Allosterically by: acetyl CoA and NADH |
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Pyruvate Dehydrogenase complex E2- name its major reactants, products, cofactors and regulators
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R: 2C pyruvate fragment
P: acetyl CoA C: CoA (co-substrate) from pantothenic acid / Lipoamide (prosthetic) Reg: feedback inhibition by acetyl CoA product |
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Pyruvate Dehydrogenase complex E3- name its major reactants, products, cofactors and regulators
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R: lipoate, FADH2, NAD+
P:oxidized lipoate on E2 and NADH C: FAD (prosthetic) from riboflavin / NAD+ (co-substrate) from niacin Reg: |
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Citric acid Cycle enzymes that produce NADH
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Isocitrate Dehydrogenase
a-Ketoglutarate Dehydrogenase Malate Dehydrogenase |
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Citric acid cycle enzyme that produces FADH2
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Succinate Dehydrogenase
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Citric acid cycle enzyme that Produces GTP
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Succinyl CoA synthetase
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