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33 Cards in this Set
- Front
- Back
Allosteric proteins
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contain distinct regulatory sites and have multiple functioning sites and display cooperativity.
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Examples of covalent modification include
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phosphorylation. acetylation. ubiquination.
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The most common strategy(ies) for enzymatic regulation are:
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multiple enzyme forms, allosteric control, reversible covalent modification, and proteolytic activation
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An allosteric interaction between a ligand and a protein is one in which:
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the binding of a molecule to a binding site affects the binding properties of another site on the protein.
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In hemoglobin, the transition from T state to R state (low to high affinity) is triggered by:
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oxygen binding.
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The fundamental cause of sickle-cell disease is a change in the structure of:
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hemoglobin.
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A small molecule that decreases the activity of an enzyme by binding to a site other than the catalytic site is termed a(n):
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allosteric inhibitor.
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Allosteric enzymes:
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usually have more than one polypeptide chain.
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How do a nucleotide and a nucleoside differ?
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A nucleotide is a nucleoside with a phosphate ester linked at the sugar 5' residue.
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In the trinucleotide pApCpG, where is the free OH group?
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at the 3' end
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The feature(s) of DNA deduced by Watson and Crick included
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two antiparallel polynucleotide chains coiled in a helix around a common axis. the pyrimidine and purine bases lie on the inside of the helix. the bases are nearly perpendicular to the axis.
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A major component of RNA but not of DNA is:
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uracil.
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The difference between a ribonucleotide and a deoxyribonucleotide is:
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deoxy- has an –H instead of an –OH at C-2.
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The phosphodiester bonds that link adjacent nucleotides in both RNA and DNA:
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join the 3' hydroxyl of one nucleotide to the 5' hydroxyl of the next.
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By definition, the 5' end of a DNA or RNA strand:
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has no nucleotide attached to the 5' hydroxyl.
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The DNA oligonucleotide abbreviated pATCGAC:
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has 6 phosphate groups.
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In a double-stranded nucleic acid, cytosine typically base-pairs with:
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guanine.
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For the oligoribonucleotide pACGUAC:
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the nucleotide at the 5' end has a phosphate on its 5' hydroxyl.
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The Watson-Crick base pairing scheme for an A–T base pair includes:
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a hydrogen bond between a keto oxygen and an extracyclic amino group.
a hydrogen bond between two ring nitrogen atoms. |
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In the Watson-Crick structure of DNA, the:
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the two strands are antiparallel.
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In the Watson-Crick model of DNA structure:
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the distance between two adjacent bases in one strand is about 3.4 Å.
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In the Watson-Crick model of DNA structure (now called B-form DNA):
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the bases occupy the interior of the helix.
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In double-stranded DNA:
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the two strands have complementary sequences.
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Adenine, Purine
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What is the name of this nucleotide
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Guanine, Purine
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What is the name of this nucleotide?
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Cytosine, Pyrimidine
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What is the name of this nucleotide
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Uracil, Pyrimidine
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What is the name of this nucleotide
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Thymine, Pyrimidine
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What is the name of this nucleotide?
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A form, B form, Z form
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name the three froms of DNA
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Name the forces in DNA
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H bonds between bases, hydrophobic bases in the middle, phosphates near water, stacking of bases (Van der Waals)
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Functions of Nucleic Acids include:
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Information molecules (DNA, RNA), Energy Metabolism (ATP), Anabolism (UDP-Glucose),
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Ribose
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This is:
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Deoxyribose
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This is:
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