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20 Cards in this Set
- Front
- Back
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What does HSP stand for in hsp 60 &70
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Heat shock protein
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what do heat shock proteins do?
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heat denatures proteins, so heat shock proteins such as HSP 60 help regulate proteins so as to help them find their correct fold (Native state).
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Molecular chaperone that helps a protein form their correct disulfide bond?
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disulfide isomerases
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peptide prolyl cis-trans isomerase (PPI) does what?
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help in the conversion of cis and trans Prolines.
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What is the job of proteases?
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1-to cleave of signal sequences that target proteins to their cellular compartment
2- cleave off pro sequences that prevent a protein from being active in the wrong cellular compartment. 3-cleave off secretion signals that cause proteins to be secreted out of the cell |
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additional atoms or molecules essential for protein structure and function
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Cofactors
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What are hemes?
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cofactors in many different proteins, serve more of a structural role.
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NAD+ and NADP+ are examples of ?
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Coenzymes
They are loosely bound molecules that move readily from enzyme to enzyme. |
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NAD+ is envolved in?
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The oxidation of other molecules
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NADP+ is envolved in?
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Usually involved in reductions in cytosol
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FAD and FMN are ...?
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Coenzymes that very tightly bound
FAD= flavin adenine dinucleotide FMN= flavin adenine mononucleotide |
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FAD and FMN bind to ..?
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Flavoproteins
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FAD is reduced to? and it does what?
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FADH2, and it is a energy carrying molecule.
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what is the relationship between Delta G (free energy) and Delta E' (reduction potential).?
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Delta G'= -nf Delta E' (stand cond)
& Delta G = -nf Delta E (NON stand) |
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n in the nersnt equation is?
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number of electrons in the rxn
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f in the nersnt equation is?
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faraday constant (96480 J/v.mol)
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Delta E' is = to?
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E' (electron acceptor)-E'(e(-) Donor)
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the Nernst equation is...?
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E=E'+(RT/nf) ln ([e doner]/[e acceptor])
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what is the purpose of coenzymes such as NADH/NADPH and FADH2?
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they are synthesized in anabolic reactions and are "activated" energy carrier that then help drive anabolic reactions.
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Rank electronegative molecules that bind to Carbon
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O>N>S>C>H
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